JPS5982091A - バイオプテリンの製法 - Google Patents

バイオプテリンの製法

Info

Publication number
JPS5982091A
JPS5982091A JP19016082A JP19016082A JPS5982091A JP S5982091 A JPS5982091 A JP S5982091A JP 19016082 A JP19016082 A JP 19016082A JP 19016082 A JP19016082 A JP 19016082A JP S5982091 A JPS5982091 A JP S5982091A
Authority
JP
Japan
Prior art keywords
biopterin
reduced
tetrahydrobiopterin
dihydrobiopterin
ascorbic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP19016082A
Other languages
English (en)
Japanese (ja)
Other versions
JPH059065B2 (da
Inventor
Nobuo Nakatsuka
中塚 伸夫
Kazumori Yamamoto
山本 和守
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suntory Ltd
Original Assignee
Suntory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suntory Ltd filed Critical Suntory Ltd
Priority to JP19016082A priority Critical patent/JPS5982091A/ja
Publication of JPS5982091A publication Critical patent/JPS5982091A/ja
Publication of JPH059065B2 publication Critical patent/JPH059065B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP19016082A 1982-10-29 1982-10-29 バイオプテリンの製法 Granted JPS5982091A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP19016082A JPS5982091A (ja) 1982-10-29 1982-10-29 バイオプテリンの製法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP19016082A JPS5982091A (ja) 1982-10-29 1982-10-29 バイオプテリンの製法

Publications (2)

Publication Number Publication Date
JPS5982091A true JPS5982091A (ja) 1984-05-11
JPH059065B2 JPH059065B2 (da) 1993-02-03

Family

ID=16253418

Family Applications (1)

Application Number Title Priority Date Filing Date
JP19016082A Granted JPS5982091A (ja) 1982-10-29 1982-10-29 バイオプテリンの製法

Country Status (1)

Country Link
JP (1) JPS5982091A (da)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4937342A (en) * 1987-11-30 1990-06-26 Kabushiki Kaisha Vitamin Kenkyusyo Intermediates for synthesizing BH4 and its derivatives
JP2007511536A (ja) * 2003-11-17 2007-05-10 バイオマリン ファーマシューティカル インコーポレイテッド 代謝障害の処置のための方法及び組成物

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4937342A (en) * 1987-11-30 1990-06-26 Kabushiki Kaisha Vitamin Kenkyusyo Intermediates for synthesizing BH4 and its derivatives
JP2007511536A (ja) * 2003-11-17 2007-05-10 バイオマリン ファーマシューティカル インコーポレイテッド 代謝障害の処置のための方法及び組成物
US9993481B2 (en) 2003-11-17 2018-06-12 Biomarin Pharmaceutical Inc. Methods and compositions for the treatment of metabolic disorders

Also Published As

Publication number Publication date
JPH059065B2 (da) 1993-02-03

Similar Documents

Publication Publication Date Title
JP2000136135A (ja) 光学活性化合物を用いた組成物
JP2525965B2 (ja) N5 −メチル−5,6,7,8−テトラヒドロ葉酸のアンモニウム塩およびその製造方法
JP2958902B2 (ja) 三つの新規非ポリグルタマートのデアザアミノプテリンと合成方法
US5124452A (en) Process for producing d,1-5-methyltetrahydrofolic acid and its salts
US5196533A (en) Cyclization of 5 amino-pyrimidines to quinoid 6,6 disubstituted dihydropteridines
Bailey et al. Synthesis of tetrahydropteridine C6-stereoisomers, including N5-formyl-(6S)-tetrahydrofolic acid
IE46402B1 (en) Process for the preparation of d, 1-5-methyltetra-hydrofolic acid
JPH0597853A (ja) Dc−89誘導体の臭化水素酸塩
EP0471820A1 (fr) Composes diastereoisomeres derivant de l'acide tetrahydrofolique, procede de preparation et utilisation dans la synthese de diastereoisomeres 6s et 6r de folates reduits
JPS5982091A (ja) バイオプテリンの製法
EP0138995B1 (en) Regulation of enzymes which utilize tetrahydrobiopterin or tetrahydrofolate cofactors with 6, 6-disubstituted-tetrahydropteridines
US5223500A (en) Stable pharmaceutical composition of alkaline or alkaline earth 5-methyl tetrahydrofolate
KR920007403B1 (ko) L(-)-테트라히드로폴산의 제조방법
CN115894456A (zh) 一种氘代吡唑氨基嘧啶类化合物、药物组合物和用途
Bailey et al. Changes in the cofactor binding domain of bovine striatal tyrosine hydroxylase at physiological pH upon cAMP-dependent phosphorylation mapped with tetrahydrobiopterin analogues
JP2674707B2 (ja) L‐ビオプテリンの製法
Rosowsky et al. Methotrexate analogs. 34. Replacement of the glutamate moiety in methotrexate and aminopterin by long-chain 2-aminoalkanedioic acids
CN112724200B (zh) 一种稳定环孢霉素a的稀释液及其应用
SUGIURA et al. Isolation and identification of 6-hydroxymethyllumazine from spinach
JPH05229948A (ja) 悪性腫瘍の治療剤または診断剤およびac8007物質の製造法
CN115716829B (zh) 一种喹啉并咪唑酮联氘代吡唑类化合物及其应用
WO2018153279A1 (en) Dihydropyridophthalazinone compounds as inhibitors of poly (adp-ribose) polymerase (parp) for treatment of diseases and method of use thereof
KR20230023750A (ko) 염소화 화합물의 제조 방법
JP2547327B2 (ja) N▲上6▼−置換nad、nadp又はfadの製造方法
GB1572138A (en) Process for the preparation of d,1-5-methyltetrahydrofolic acid