JPS5931746A - ペプチドのｎ―アシル誘導体 - Google Patents

ペプチドのｎ―アシル誘導体

Info

Publication number
JPS5931746A
JPS5931746A JP58127033A JP12703383A JPS5931746A JP S5931746 A JPS5931746 A JP S5931746A JP 58127033 A JP58127033 A JP 58127033A JP 12703383 A JP12703383 A JP 12703383A JP S5931746 A JPS5931746 A JP S5931746A
Authority
JP
Japan
Prior art keywords
group
ylcarbonyl
methanol
formula
glycinamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP58127033A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0441156B2 (https=
Inventor
ハンス・ペ−タ−・アルブレヒト
ホルスト・クライスコツト
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Publication of JPS5931746A publication Critical patent/JPS5931746A/ja
Publication of JPH0441156B2 publication Critical patent/JPH0441156B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C07K5/0823—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Pro-amino acid; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pyrrole Compounds (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP58127033A 1982-07-14 1983-07-14 ペプチドのｎ―アシル誘導体 Granted JPS5931746A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19823226241 DE3226241A1 (de) 1982-07-14 1982-07-14 N-acylderivate von peptiden, ihre herstellung und verwendung bei der bekaempfung von krankheiten und mittel dafuer
DE3226241.8 1982-07-14

Publications (2)

Publication Number Publication Date
JPS5931746A true JPS5931746A (ja) 1984-02-20
JPH0441156B2 JPH0441156B2 (https=) 1992-07-07

Family

ID=6168357

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58127033A Granted JPS5931746A (ja) 1982-07-14 1983-07-14 ペプチドのｎ―アシル誘導体

Country Status (6)

Country Link
US (1) US4610817A (https=)
EP (1) EP0099057B1 (https=)
JP (1) JPS5931746A (https=)
AT (1) ATE30238T1 (https=)
CA (1) CA1257748A (https=)
DE (2) DE3226241A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9113219D0 (en) * 1991-06-19 1991-08-07 Fujisawa Pharmaceutical Co Peptide compound,processes for preparation thereof and pharmaceutical composition comprising the same
US5767083A (en) * 1994-05-04 1998-06-16 Innapharma, Inc. Tri-, tetra-, penta-, and polypeptides and their therapeutic use as an antidepressant agent
US6767897B2 (en) * 1994-05-04 2004-07-27 Innapharma, Inc. Therapeutic uses of tri-, tetra-, penta-, and polypeptides
US5589460A (en) * 1994-05-04 1996-12-31 Innapharma, Inc. Tri-, tetra-, penta-, and polypeptides and their therapeutic use as an antidepressant agent

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1085916A (en) * 1964-12-01 1967-10-04 Nat Res Dev O-acyl hydroxylamines
US4041023A (en) * 1976-04-14 1977-08-09 Hoffmann-La Roche Inc. Labelled peptides
JPS5632307A (en) * 1979-08-21 1981-04-01 Bergwerksverband Gmbh Manufacture of sulfur from gas containing sulfur dioxide

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3795738A (en) * 1972-12-26 1974-03-05 Abbott Lab Use of l-propyl l-leucyl glycine amide to treat parkinson's disease
US4018912A (en) * 1975-07-28 1977-04-19 Ayerst Mckenna And Harrison Ltd. Tripeptide derivatives with central nervous system activity and preparation thereof
GB1592552A (en) * 1976-12-10 1981-07-08 Inst Nat Sante Rech Med Pseudopeptides used as medicaments
WO1980000216A1 (en) * 1978-07-10 1980-02-21 Univ Illinois Inhibition by peptides of tolerance to and dependence on morphine
US4278595A (en) * 1979-12-10 1981-07-14 Vega Laboratories, Inc. Orally active MIF analogs with an effect on the central nervous system
US4395401A (en) * 1981-09-09 1983-07-26 Smithkline Beckman Corporation Renally active dipeptides

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1085916A (en) * 1964-12-01 1967-10-04 Nat Res Dev O-acyl hydroxylamines
US4041023A (en) * 1976-04-14 1977-08-09 Hoffmann-La Roche Inc. Labelled peptides
JPS5632307A (en) * 1979-08-21 1981-04-01 Bergwerksverband Gmbh Manufacture of sulfur from gas containing sulfur dioxide

Also Published As

Publication number Publication date
EP0099057A3 (en) 1984-09-12
JPH0441156B2 (https=) 1992-07-07
DE3374066D1 (en) 1987-11-19
EP0099057B1 (de) 1987-10-14
DE3226241A1 (de) 1984-01-26
EP0099057A2 (de) 1984-01-25
ATE30238T1 (de) 1987-10-15
US4610817A (en) 1986-09-09
CA1257748A (en) 1989-07-18

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