JPS5919941B2 - 新規１，４−ベンゾジアゼピンの製法 - Google Patents

新規１，４−ベンゾジアゼピンの製法

Info

Publication number
JPS5919941B2
JPS5919941B2 JP50052422A JP5242275A JPS5919941B2 JP S5919941 B2 JPS5919941 B2 JP S5919941B2 JP 50052422 A JP50052422 A JP 50052422A JP 5242275 A JP5242275 A JP 5242275A JP S5919941 B2 JPS5919941 B2 JP S5919941B2
Authority
JP
Japan
Prior art keywords
mol
benzodiazepine
formula
chloro
yield
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP50052422A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5116684A (en
Inventor
フエレル サラト カルロス
コロヌ リエラ フアン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RABORATORIOSU FUERERU SOC RIMITAADA
Original Assignee
RABORATORIOSU FUERERU SOC RIMITAADA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ES425843A external-priority patent/ES425843A1/es
Priority claimed from ES425842A external-priority patent/ES425842A1/es
Priority claimed from ES434706A external-priority patent/ES434706A2/es
Priority claimed from ES434707A external-priority patent/ES434707A2/es
Application filed by RABORATORIOSU FUERERU SOC RIMITAADA filed Critical RABORATORIOSU FUERERU SOC RIMITAADA
Publication of JPS5116684A publication Critical patent/JPS5116684A/ja
Publication of JPS5919941B2 publication Critical patent/JPS5919941B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/26—Preparation from compounds already containing the benzodiazepine skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP50052422A 1974-04-30 1975-04-30 新規１，４−ベンゾジアゼピンの製法 Expired JPS5919941B2 (ja)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
ES425842 1974-04-30
ES425843A ES425843A1 (es) 1974-04-30 1974-04-30 Procedimiento para la obtencion de una nueva 1,4-benzodia- zepina.
ES425842A ES425842A1 (es) 1974-04-30 1974-04-30 Procedimiento para la obtencion de una nueva 1,4-benzodia- zepina.
ES425843 1974-04-30
ES434706 1975-02-07
ES434707 1975-02-07
ES434706A ES434706A2 (es) 1975-02-07 1975-02-07 Procedimiento para la obtencion de una nueva 1,4-benzodiaze-pina.
ES434707A ES434707A2 (es) 1975-02-07 1975-02-07 Procedimiento para la obtencion de una nueva 1,4-benzodiaze-pina.

Publications (2)

Publication Number Publication Date
JPS5116684A JPS5116684A (en) 1976-02-10
JPS5919941B2 true JPS5919941B2 (ja) 1984-05-09

Family

ID=27443992

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50052422A Expired JPS5919941B2 (ja) 1974-04-30 1975-04-30 新規１，４−ベンゾジアゼピンの製法

Country Status (6)

Country Link
JP (1) JPS5919941B2 (enExample)
CA (1) CA1027561A (enExample)
DE (1) DE2519318C2 (enExample)
FR (1) FR2269349B1 (enExample)
GB (1) GB1486730A (enExample)
NL (1) NL173269C (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2852606A1 (de) * 1977-12-14 1979-06-21 Gerot Pharmazeutika 3-di-n-propyl-acetoxy-benzodiazepin-2-one und verfahren zu deren herstellung

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL289735A (enExample) * 1962-03-09
US3801568A (en) * 1972-02-07 1974-04-02 American Home Prod Optically active 1,3-dihydro-3-substituted 5-phenyl-2h-1,4-benzodiazepin-2-ones and process for their separation

Also Published As

Publication number Publication date
JPS5116684A (en) 1976-02-10
DE2519318C2 (de) 1983-05-05
FR2269349A1 (enExample) 1975-11-28
GB1486730A (en) 1977-09-21
NL7505059A (nl) 1975-11-03
FR2269349B1 (enExample) 1979-03-16
CA1027561A (en) 1978-03-07
NL173269C (nl) 1984-01-02
DE2519318A1 (de) 1975-11-06

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