CA1027561A - Pharmacologically active 1,4-benzodiazepins and process for their preparation - Google Patents

Pharmacologically active 1,4-benzodiazepins and process for their preparation

Info

Publication number
CA1027561A
CA1027561A CA225,890A CA225890A CA1027561A CA 1027561 A CA1027561 A CA 1027561A CA 225890 A CA225890 A CA 225890A CA 1027561 A CA1027561 A CA 1027561A
Authority
CA
Canada
Prior art keywords
benzodiazepins
preparation
pharmacologically active
pharmacologically
active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA225,890A
Other languages
English (en)
French (fr)
Other versions
CA225890S (en
Inventor
Juan Colome
Carlos Ferrer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferrer Internacional SA
Original Assignee
Ferrer Internacional SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ES425843A external-priority patent/ES425843A1/es
Priority claimed from ES425842A external-priority patent/ES425842A1/es
Priority claimed from ES434706A external-priority patent/ES434706A2/es
Priority claimed from ES434707A external-priority patent/ES434707A2/es
Application filed by Ferrer Internacional SA filed Critical Ferrer Internacional SA
Application granted granted Critical
Publication of CA1027561A publication Critical patent/CA1027561A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/26—Preparation from compounds already containing the benzodiazepine skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA225,890A 1974-04-30 1975-04-30 Pharmacologically active 1,4-benzodiazepins and process for their preparation Expired CA1027561A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
ES425843A ES425843A1 (es) 1974-04-30 1974-04-30 Procedimiento para la obtencion de una nueva 1,4-benzodia- zepina.
ES425842A ES425842A1 (es) 1974-04-30 1974-04-30 Procedimiento para la obtencion de una nueva 1,4-benzodia- zepina.
ES434706A ES434706A2 (es) 1975-02-07 1975-02-07 Procedimiento para la obtencion de una nueva 1,4-benzodiaze-pina.
ES434707A ES434707A2 (es) 1975-02-07 1975-02-07 Procedimiento para la obtencion de una nueva 1,4-benzodiaze-pina.

Publications (1)

Publication Number Publication Date
CA1027561A true CA1027561A (en) 1978-03-07

Family

ID=27443992

Family Applications (1)

Application Number Title Priority Date Filing Date
CA225,890A Expired CA1027561A (en) 1974-04-30 1975-04-30 Pharmacologically active 1,4-benzodiazepins and process for their preparation

Country Status (6)

Country Link
JP (1) JPS5919941B2 (enExample)
CA (1) CA1027561A (enExample)
DE (1) DE2519318C2 (enExample)
FR (1) FR2269349B1 (enExample)
GB (1) GB1486730A (enExample)
NL (1) NL173269C (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2852606A1 (de) * 1977-12-14 1979-06-21 Gerot Pharmazeutika 3-di-n-propyl-acetoxy-benzodiazepin-2-one und verfahren zu deren herstellung

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL289735A (enExample) * 1962-03-09
US3801568A (en) * 1972-02-07 1974-04-02 American Home Prod Optically active 1,3-dihydro-3-substituted 5-phenyl-2h-1,4-benzodiazepin-2-ones and process for their separation

Also Published As

Publication number Publication date
JPS5919941B2 (ja) 1984-05-09
JPS5116684A (en) 1976-02-10
DE2519318C2 (de) 1983-05-05
FR2269349A1 (enExample) 1975-11-28
GB1486730A (en) 1977-09-21
NL7505059A (nl) 1975-11-03
FR2269349B1 (enExample) 1979-03-16
NL173269C (nl) 1984-01-02
DE2519318A1 (de) 1975-11-06

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