JPS59193882A - ６，１１−ジヒドロ−１１−オキソジベンズ〔ｂ，ｅ〕−オキセピンの置換アルキルアミン誘導体およびその製法 - Google Patents

６，１１−ジヒドロ−１１−オキソジベンズ〔ｂ，ｅ〕−オキセピンの置換アルキルアミン誘導体およびその製法

Info

Publication number
JPS59193882A
JPS59193882A JP59044148A JP4414884A JPS59193882A JP S59193882 A JPS59193882 A JP S59193882A JP 59044148 A JP59044148 A JP 59044148A JP 4414884 A JP4414884 A JP 4414884A JP S59193882 A JPS59193882 A JP S59193882A
Authority
JP
Japan
Prior art keywords
dihydro
formula
compound
oxodibenz
oxepin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP59044148A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0415789B2 (enExample
Inventor
ロレンス・レオ・マ−チン
リンダ・ルイ−ズ・セテスカ−ク
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Hoechst Roussel Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharmaceuticals Inc filed Critical Hoechst Roussel Pharmaceuticals Inc
Publication of JPS59193882A publication Critical patent/JPS59193882A/ja
Publication of JPH0415789B2 publication Critical patent/JPH0415789B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/12—[b,e]-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Epoxy Compounds (AREA)
JP59044148A 1983-03-10 1984-03-09 ６，１１−ジヒドロ−１１−オキソジベンズ〔ｂ，ｅ〕−オキセピンの置換アルキルアミン誘導体およびその製法 Granted JPS59193882A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/474,106 US4526891A (en) 1983-03-10 1983-03-10 Substituted alkyl amine derivatives of 6,11-dihydro-11-oxodibenz[b,e]oxepins
US474106 1983-03-10

Publications (2)

Publication Number Publication Date
JPS59193882A true JPS59193882A (ja) 1984-11-02
JPH0415789B2 JPH0415789B2 (enExample) 1992-03-19

Family

ID=23882204

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59044148A Granted JPS59193882A (ja) 1983-03-10 1984-03-09 ６，１１−ジヒドロ−１１−オキソジベンズ〔ｂ，ｅ〕−オキセピンの置換アルキルアミン誘導体およびその製法

Country Status (6)

Country Link
US (1) US4526891A (enExample)
EP (1) EP0119540B1 (enExample)
JP (1) JPS59193882A (enExample)
AT (1) ATE55768T1 (enExample)
DE (1) DE3483011D1 (enExample)
GR (1) GR81771B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840749A (en) * 1989-08-25 1998-11-24 Hoechst Marion Roussel, Inc. N-hydroxy-dibenz b,e!oxepinalkylamines, N-hydroxy-dibenz b,e!oxepinalkanoic acid amides and related heterocyclic analogues
GB0522431D0 (en) * 2005-11-03 2005-12-14 Astrazeneca Ab Chemical process
DE102013101428A1 (de) 2013-02-13 2014-08-14 Airex Ag Biegeholzlaminat sowie darauf hergestelltes gebogenes Formteil

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3629267A (en) * 1968-10-28 1971-12-21 Smith Kline French Lab Benzoheterocyclicalkyl derivatives of 4-(2-keto -1-benzimidazolinyl)-piperidine 4-(2-keto - 1 - benzimidazolinyl) -1 2 3 6 tetrahydropyridine 1 - phenyl - 1 3 8-triazaspiro(4 5)decan - 4 - one and 2 4 9-triazaspiro(5 5)undecan-1 3 5-trione
YU204274A (en) * 1973-07-24 1982-06-30 Hoechst Ag Process for preparing new dibenzoxepin derivatives
US4585788A (en) * 1973-09-06 1986-04-29 American Hoechst Corporation 6,11-dihydrodibenz[b,e]oxepin-acetic acids and derivatives
ES444144A1 (es) * 1975-01-14 1977-08-16 Hoechst Ag Un procedimiento para la preparacion de un acido 6,11-dihi- dro-11-oxo-dibenz (b, e) oxepin-alcanoico.
US4107322A (en) * 1976-06-03 1978-08-15 American Hoechst Corporation Benzyl and related esters of 6,11-dihydrodibenz[b,e]oxepin-acetic acids
US4205170A (en) * 1976-12-03 1980-05-27 Nippon Chemiphar Company, Limited Propionic acid derivatives
US4282365A (en) * 1978-11-24 1981-08-04 Merck & Co., Inc. Dibenz[b,e]oxepin compounds
US4515946A (en) * 1981-12-23 1985-05-07 Hoechst-Roussel Pharmaceuticals Inc. 6,11-Dihydro-11-oxo-dibenz-[b,e]oxepin derivatives

Also Published As

Publication number Publication date
DE3483011D1 (de) 1990-09-27
EP0119540A3 (en) 1985-05-15
JPH0415789B2 (enExample) 1992-03-19
EP0119540B1 (en) 1990-08-22
US4526891A (en) 1985-07-02
GR81771B (enExample) 1984-12-12
EP0119540A2 (en) 1984-09-26
ATE55768T1 (de) 1990-09-15

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