JPS59175428A - 抗齲蝕剤 - Google Patents
抗齲蝕剤Info
- Publication number
- JPS59175428A JPS59175428A JP5120383A JP5120383A JPS59175428A JP S59175428 A JPS59175428 A JP S59175428A JP 5120383 A JP5120383 A JP 5120383A JP 5120383 A JP5120383 A JP 5120383A JP S59175428 A JPS59175428 A JP S59175428A
- Authority
- JP
- Japan
- Prior art keywords
- agent
- lactone
- streptococcus mutans
- side effects
- cariostatic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000004075 cariostatic agent Substances 0.000 title abstract 2
- 150000002596 lactones Chemical class 0.000 claims abstract description 13
- GHBSPIPJMLAMEP-UHFFFAOYSA-N 6-pentyloxan-2-one Chemical compound CCCCCC1CCCC(=O)O1 GHBSPIPJMLAMEP-UHFFFAOYSA-N 0.000 claims abstract description 3
- SKQYTJLYRIFFCO-UHFFFAOYSA-N delta-Tetradecalactone Chemical compound CCCCCCCCCC1CCCC(=O)O1 SKQYTJLYRIFFCO-UHFFFAOYSA-N 0.000 claims abstract 2
- 230000000694 effects Effects 0.000 abstract description 18
- 239000003795 chemical substances by application Substances 0.000 abstract description 10
- 241000194019 Streptococcus mutans Species 0.000 abstract description 9
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 abstract description 8
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 8
- 239000000796 flavoring agent Substances 0.000 abstract description 7
- 239000003242 anti bacterial agent Substances 0.000 abstract description 6
- 230000003115 biocidal effect Effects 0.000 abstract description 5
- 235000019634 flavors Nutrition 0.000 abstract description 5
- 229960003276 erythromycin Drugs 0.000 abstract description 4
- 235000013305 food Nutrition 0.000 abstract description 3
- 231100000957 no side effect Toxicity 0.000 abstract description 3
- -1 d-decalactone Chemical class 0.000 abstract description 2
- 208000002925 dental caries Diseases 0.000 abstract description 2
- 244000005706 microflora Species 0.000 abstract description 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- 230000000248 cariostatic effect Effects 0.000 abstract 1
- 239000000551 dentifrice Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 210000000214 mouth Anatomy 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 description 12
- 206010054107 Nodule Diseases 0.000 description 7
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 6
- 229930006000 Sucrose Natural products 0.000 description 6
- 239000005720 sucrose Substances 0.000 description 6
- 239000003205 fragrance Substances 0.000 description 5
- 229920001503 Glucan Polymers 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 238000011160 research Methods 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 229940088710 antibiotic agent Drugs 0.000 description 3
- 239000011230 binding agent Substances 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 210000002421 cell wall Anatomy 0.000 description 2
- 235000013355 food flavoring agent Nutrition 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- VVOAZFWZEDHOOU-UHFFFAOYSA-N magnolol Chemical compound OC1=CC=C(CC=C)C=C1C1=CC(CC=C)=CC=C1O VVOAZFWZEDHOOU-UHFFFAOYSA-N 0.000 description 2
- 239000000341 volatile oil Substances 0.000 description 2
- 238000003466 welding Methods 0.000 description 2
- 208000002064 Dental Plaque Diseases 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 229930182555 Penicillin Natural products 0.000 description 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 description 1
- 241000607768 Shigella Species 0.000 description 1
- 241000194023 Streptococcus sanguinis Species 0.000 description 1
- 230000001430 anti-depressive effect Effects 0.000 description 1
- 239000000935 antidepressant agent Substances 0.000 description 1
- 229940005513 antidepressants Drugs 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 229940112822 chewing gum Drugs 0.000 description 1
- 235000015218 chewing gum Nutrition 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- 230000003628 erosive effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000002101 lytic effect Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 239000002324 mouth wash Substances 0.000 description 1
- 229940049954 penicillin Drugs 0.000 description 1
- 238000000053 physical method Methods 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 230000002250 progressing effect Effects 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 239000000606 toothpaste Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Pyrane Compounds (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5120383A JPS59175428A (ja) | 1983-03-26 | 1983-03-26 | 抗齲蝕剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5120383A JPS59175428A (ja) | 1983-03-26 | 1983-03-26 | 抗齲蝕剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS59175428A true JPS59175428A (ja) | 1984-10-04 |
| JPH0320364B2 JPH0320364B2 (enrdf_load_stackoverflow) | 1991-03-19 |
Family
ID=12880336
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP5120383A Granted JPS59175428A (ja) | 1983-03-26 | 1983-03-26 | 抗齲蝕剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS59175428A (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006255781A (ja) * | 2005-02-16 | 2006-09-28 | Honda Motor Co Ltd | 絞り成形装置 |
| JP2012246235A (ja) * | 2011-05-26 | 2012-12-13 | Kao Corp | オートインデューサー−２阻害剤 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3985870A (en) * | 1971-03-24 | 1976-10-12 | Pfanstiehl Laboratories, Inc. | Toothpastes |
-
1983
- 1983-03-26 JP JP5120383A patent/JPS59175428A/ja active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3985870A (en) * | 1971-03-24 | 1976-10-12 | Pfanstiehl Laboratories, Inc. | Toothpastes |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006255781A (ja) * | 2005-02-16 | 2006-09-28 | Honda Motor Co Ltd | 絞り成形装置 |
| JP2012246235A (ja) * | 2011-05-26 | 2012-12-13 | Kao Corp | オートインデューサー−２阻害剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0320364B2 (enrdf_load_stackoverflow) | 1991-03-19 |
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