JPS59137412A - 貼付剤 - Google Patents
貼付剤Info
- Publication number
- JPS59137412A JPS59137412A JP1136583A JP1136583A JPS59137412A JP S59137412 A JPS59137412 A JP S59137412A JP 1136583 A JP1136583 A JP 1136583A JP 1136583 A JP1136583 A JP 1136583A JP S59137412 A JPS59137412 A JP S59137412A
- Authority
- JP
- Japan
- Prior art keywords
- glycol
- water
- indomethacin
- soluble polymer
- urea
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000011505 plaster Substances 0.000 title abstract 3
- CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 claims abstract description 24
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims abstract description 12
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims abstract description 12
- 229960000905 indomethacin Drugs 0.000 claims abstract description 12
- 229920003169 water-soluble polymer Polymers 0.000 claims abstract description 9
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims abstract description 6
- 239000000203 mixture Substances 0.000 claims abstract description 6
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims abstract description 5
- 239000004202 carbamide Substances 0.000 claims abstract description 5
- 229920000609 methyl cellulose Polymers 0.000 claims abstract description 4
- 239000001923 methylcellulose Substances 0.000 claims abstract description 4
- 239000002202 Polyethylene glycol Substances 0.000 claims abstract description 3
- 229920001223 polyethylene glycol Polymers 0.000 claims abstract description 3
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims abstract description 3
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims abstract description 3
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims abstract description 3
- 150000001875 compounds Chemical class 0.000 claims description 9
- 150000002334 glycols Chemical class 0.000 claims description 5
- 239000004615 ingredient Substances 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- 239000000853 adhesive Substances 0.000 claims 2
- 230000001070 adhesive effect Effects 0.000 claims 2
- 230000000694 effects Effects 0.000 abstract description 9
- 239000003795 chemical substances by application Substances 0.000 abstract description 3
- 239000004372 Polyvinyl alcohol Substances 0.000 abstract description 2
- 230000000202 analgesic effect Effects 0.000 abstract description 2
- 230000003110 anti-inflammatory effect Effects 0.000 abstract description 2
- 230000001754 anti-pyretic effect Effects 0.000 abstract description 2
- 229920002451 polyvinyl alcohol Polymers 0.000 abstract description 2
- 239000011248 coating agent Substances 0.000 abstract 2
- 238000000576 coating method Methods 0.000 abstract 2
- 239000000758 substrate Substances 0.000 abstract 2
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 abstract 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 abstract 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 1
- 235000010981 methylcellulose Nutrition 0.000 abstract 1
- 235000019422 polyvinyl alcohol Nutrition 0.000 abstract 1
- BBEAQIROQSPTKN-UHFFFAOYSA-N pyrene Chemical compound C1=CC=C2C=CC3=CC=CC4=CC=C1C2=C43 BBEAQIROQSPTKN-UHFFFAOYSA-N 0.000 description 4
- 238000010521 absorption reaction Methods 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- QIGBRXMKCJKVMJ-UHFFFAOYSA-N Hydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 description 2
- GVEPBJHOBDJJJI-UHFFFAOYSA-N fluoranthrene Natural products C1=CC(C2=CC=CC=C22)=C3C2=CC=CC3=C1 GVEPBJHOBDJJJI-UHFFFAOYSA-N 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 1
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 description 1
- 208000004998 Abdominal Pain Diseases 0.000 description 1
- 241000282472 Canis lupus familiaris Species 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 239000001856 Ethyl cellulose Substances 0.000 description 1
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 241000700159 Rattus Species 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000000730 antalgic agent Substances 0.000 description 1
- 239000002221 antipyretic Substances 0.000 description 1
- 229940125716 antipyretic agent Drugs 0.000 description 1
- 230000004596 appetite loss Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 229920001249 ethyl cellulose Polymers 0.000 description 1
- 235000019325 ethyl cellulose Nutrition 0.000 description 1
- 208000013088 frontal headache Diseases 0.000 description 1
- 208000019017 loss of appetite Diseases 0.000 description 1
- 235000021266 loss of appetite Nutrition 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 229940105132 myristate Drugs 0.000 description 1
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 229920005615 natural polymer Polymers 0.000 description 1
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 description 1
- 239000004584 polyacrylic acid Substances 0.000 description 1
- 229920001451 polypropylene glycol Polymers 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 229920001059 synthetic polymer Chemical class 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1136583A JPS59137412A (ja) | 1983-01-28 | 1983-01-28 | 貼付剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1136583A JPS59137412A (ja) | 1983-01-28 | 1983-01-28 | 貼付剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS59137412A true JPS59137412A (ja) | 1984-08-07 |
| JPH0437048B2 JPH0437048B2 (enrdf_load_stackoverflow) | 1992-06-18 |
Family
ID=11775995
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1136583A Granted JPS59137412A (ja) | 1983-01-28 | 1983-01-28 | 貼付剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS59137412A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05331064A (ja) * | 1992-05-26 | 1993-12-14 | Sekisui Chem Co Ltd | 消炎鎮痛貼付剤 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5798209A (en) * | 1980-12-09 | 1982-06-18 | Kowa Co | Remedy for dermatopathy for external use |
| JPS57140711A (en) * | 1981-02-26 | 1982-08-31 | Teika Seiyaku Kk | Poultice for anti-inflammatory and analgesic use and its preparation |
-
1983
- 1983-01-28 JP JP1136583A patent/JPS59137412A/ja active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5798209A (en) * | 1980-12-09 | 1982-06-18 | Kowa Co | Remedy for dermatopathy for external use |
| JPS57140711A (en) * | 1981-02-26 | 1982-08-31 | Teika Seiyaku Kk | Poultice for anti-inflammatory and analgesic use and its preparation |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05331064A (ja) * | 1992-05-26 | 1993-12-14 | Sekisui Chem Co Ltd | 消炎鎮痛貼付剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0437048B2 (enrdf_load_stackoverflow) | 1992-06-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4678666A (en) | Topical anti-inflammatory compositions | |
| US5807568A (en) | Enhanced delivery of topical compositions containing flurbiprofen | |
| CA2121065C (en) | External anti-inflammatory and analgesic plaster preparation | |
| JPH03193728A (ja) | 消炎鎮痛貼付剤 | |
| US4670254A (en) | Gel preparations for topical application of diclofenac sodium | |
| AU2010204986A1 (en) | Transdermal administration of tamsulosin | |
| US6054484A (en) | Transparent aqueous solution of diclofenac sodium and medicinal compositions with the use of the same | |
| JPH026407A (ja) | 炎症抑制剤ゲル | |
| WO2011049058A1 (ja) | ジクロフェナクナトリウム含有水性貼付剤 | |
| JP5590846B2 (ja) | 外用医薬組成物 | |
| JP2920451B2 (ja) | 消炎鎮痛貼付剤 | |
| US5496819A (en) | Antiphlogistic-analgesic plaster comprising triacetin and piroxicam | |
| JP2001199883A (ja) | 消炎鎮痛外用剤 | |
| JPS59137412A (ja) | 貼付剤 | |
| JP2001302503A (ja) | 貼付剤 | |
| JP5091472B2 (ja) | 粘着剤及び貼付剤 | |
| JPH09208463A (ja) | 経皮吸収性に優れた消炎鎮痛組成物 | |
| KR100552650B1 (ko) | 피록시캄 함유 소염진통용 플라스터 | |
| JP2018172340A (ja) | フルルビプロフェン含有含水系貼付剤 | |
| JPS6160608A (ja) | ジクロフェナック湿布剤 | |
| JPH069394A (ja) | 外用消炎鎮痛液剤 | |
| JP4038580B2 (ja) | 貼付剤 | |
| JPH06279288A (ja) | パップ剤 | |
| JPH04217920A (ja) | 経皮吸収組成物 | |
| JP2819195B2 (ja) | 消炎鎮痛貼付剤 |