JPS58876B2 - Ｆｒ −１９２３ ブツシツノ セイゾウホウホウ - Google Patents
Ｆｒ −１９２３ ブツシツノ セイゾウホウホウInfo
- Publication number
- JPS58876B2 JPS58876B2 JP50139405A JP13940575A JPS58876B2 JP S58876 B2 JPS58876 B2 JP S58876B2 JP 50139405 A JP50139405 A JP 50139405A JP 13940575 A JP13940575 A JP 13940575A JP S58876 B2 JPS58876 B2 JP S58876B2
- Authority
- JP
- Japan
- Prior art keywords
- group
- substance
- substituted alkylene
- culture
- alkylene group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000126 substance Substances 0.000 claims description 27
- 238000004519 manufacturing process Methods 0.000 claims description 12
- 241000894006 Bacteria Species 0.000 claims description 11
- 238000012258 culturing Methods 0.000 claims description 9
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims description 6
- 150000001735 carboxylic acids Chemical class 0.000 claims description 6
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims description 4
- JXOHGGNKMLTUBP-HSUXUTPPSA-N shikimic acid Chemical compound O[C@@H]1CC(C(O)=O)=C[C@@H](O)[C@H]1O JXOHGGNKMLTUBP-HSUXUTPPSA-N 0.000 claims description 4
- JXOHGGNKMLTUBP-JKUQZMGJSA-N shikimic acid Natural products O[C@@H]1CC(C(O)=O)=C[C@H](O)[C@@H]1O JXOHGGNKMLTUBP-JKUQZMGJSA-N 0.000 claims description 4
- 239000004471 Glycine Substances 0.000 claims description 3
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 claims description 2
- UKAUYVFTDYCKQA-UHFFFAOYSA-N -2-Amino-4-hydroxybutanoic acid Natural products OC(=O)C(N)CCO UKAUYVFTDYCKQA-UHFFFAOYSA-N 0.000 claims description 2
- QWCKQJZIFLGMSD-UHFFFAOYSA-N 2-Aminobutanoic acid Natural products CCC(N)C(O)=O QWCKQJZIFLGMSD-UHFFFAOYSA-N 0.000 claims description 2
- QWCKQJZIFLGMSD-GSVOUGTGSA-N D-alpha-aminobutyric acid Chemical compound CC[C@@H](N)C(O)=O QWCKQJZIFLGMSD-GSVOUGTGSA-N 0.000 claims description 2
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 claims description 2
- UKAUYVFTDYCKQA-VKHMYHEASA-N L-homoserine Chemical compound OC(=O)[C@@H](N)CCO UKAUYVFTDYCKQA-VKHMYHEASA-N 0.000 claims description 2
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims description 2
- 235000004279 alanine Nutrition 0.000 claims description 2
- PECYZEOJVXMISF-UHFFFAOYSA-N 3-aminoalanine Chemical compound [NH3+]CC(N)C([O-])=O PECYZEOJVXMISF-UHFFFAOYSA-N 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 description 28
- 239000002609 medium Substances 0.000 description 12
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 12
- 238000011218 seed culture Methods 0.000 description 12
- 239000001963 growth medium Substances 0.000 description 9
- 241000520858 Nocardia uniformis Species 0.000 description 6
- 238000012474 bioautography Methods 0.000 description 6
- 229910052697 platinum Inorganic materials 0.000 description 6
- 239000013587 production medium Substances 0.000 description 6
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 5
- 238000004166 bioassay Methods 0.000 description 5
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 4
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 description 4
- 229910052799 carbon Inorganic materials 0.000 description 4
- 125000004432 carbon atom Chemical group C* 0.000 description 4
- -1 methylene, ethylene, propylene Chemical group 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 150000003839 salts Chemical class 0.000 description 4
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 3
- 239000005977 Ethylene Substances 0.000 description 3
- 239000013078 crystal Substances 0.000 description 3
- 238000012136 culture method Methods 0.000 description 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 3
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 description 3
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 3
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 3
- 229960004441 tyrosine Drugs 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 125000004442 acylamino group Chemical group 0.000 description 2
- 125000003277 amino group Chemical group 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- HHLFWLYXYJOTON-UHFFFAOYSA-N glyoxylic acid Chemical compound OC(=O)C=O HHLFWLYXYJOTON-UHFFFAOYSA-N 0.000 description 2
- 235000012054 meals Nutrition 0.000 description 2
- 239000002244 precipitate Substances 0.000 description 2
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 2
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- UECDWMGGNAYEKF-JTQLQIEISA-N (2s)-n-acetyl-2-amino-3-(4-hydroxyphenyl)propanamide Chemical compound CC(=O)NC(=O)[C@@H](N)CC1=CC=C(O)C=C1 UECDWMGGNAYEKF-JTQLQIEISA-N 0.000 description 1
- BMVXCPBXGZKUPN-UHFFFAOYSA-N 1-hexanamine Chemical class CCCCCCN BMVXCPBXGZKUPN-UHFFFAOYSA-N 0.000 description 1
- YSFQIJDACSFIOH-UHFFFAOYSA-N 2,2-diaminopropanoic acid Chemical class CC(N)(N)C(O)=O YSFQIJDACSFIOH-UHFFFAOYSA-N 0.000 description 1
- NEAQRZUHTPSBBM-UHFFFAOYSA-N 2-hydroxy-3,3-dimethyl-7-nitro-4h-isoquinolin-1-one Chemical class C1=C([N+]([O-])=O)C=C2C(=O)N(O)C(C)(C)CC2=C1 NEAQRZUHTPSBBM-UHFFFAOYSA-N 0.000 description 1
- YHXHKYRQLYQUIH-UHFFFAOYSA-N 4-hydroxymandelic acid Chemical compound OC(=O)C(O)C1=CC=C(O)C=C1 YHXHKYRQLYQUIH-UHFFFAOYSA-N 0.000 description 1
- KKADPXVIOXHVKN-UHFFFAOYSA-N 4-hydroxyphenylpyruvic acid Chemical compound OC(=O)C(=O)CC1=CC=C(O)C=C1 KKADPXVIOXHVKN-UHFFFAOYSA-N 0.000 description 1
- 101100313763 Arabidopsis thaliana TIM22-2 gene Proteins 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 108010068370 Glutens Proteins 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- 239000005909 Kieselgur Substances 0.000 description 1
- WRUZLCLJULHLEY-UHFFFAOYSA-N N-(p-hydroxyphenyl)glycine Chemical compound OC(=O)CNC1=CC=C(O)C=C1 WRUZLCLJULHLEY-UHFFFAOYSA-N 0.000 description 1
- CAHKINHBCWCHCF-JTQLQIEISA-N N-acetyl-L-tyrosine Chemical compound CC(=O)N[C@H](C(O)=O)CC1=CC=C(O)C=C1 CAHKINHBCWCHCF-JTQLQIEISA-N 0.000 description 1
- 239000001888 Peptone Substances 0.000 description 1
- 108010080698 Peptones Proteins 0.000 description 1
- QOSMNYMQXIVWKY-UHFFFAOYSA-N Propyl levulinate Chemical compound CCCOC(=O)CCC(C)=O QOSMNYMQXIVWKY-UHFFFAOYSA-N 0.000 description 1
- 241000589516 Pseudomonas Species 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 125000002252 acyl group Chemical group 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 125000001589 carboacyl group Chemical group 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 235000012343 cottonseed oil Nutrition 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 150000002169 ethanolamines Chemical class 0.000 description 1
- SBBWEQLNKVHYCX-JTQLQIEISA-N ethyl L-tyrosinate Chemical compound CCOC(=O)[C@@H](N)CC1=CC=C(O)C=C1 SBBWEQLNKVHYCX-JTQLQIEISA-N 0.000 description 1
- 125000004494 ethyl ester group Chemical group 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 235000013312 flour Nutrition 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 235000021312 gluten Nutrition 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 229940042795 hydrazides for tuberculosis treatment Drugs 0.000 description 1
- 150000007529 inorganic bases Chemical class 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 239000013028 medium composition Substances 0.000 description 1
- 229910001463 metal phosphate Inorganic materials 0.000 description 1
- GBMDVOWEEQVZKZ-UHFFFAOYSA-N methanol;hydrate Chemical compound O.OC GBMDVOWEEQVZKZ-UHFFFAOYSA-N 0.000 description 1
- 150000004702 methyl esters Chemical class 0.000 description 1
- 229960001682 n-acetyltyrosine Drugs 0.000 description 1
- RSIPQHOWTCNEBI-UHFFFAOYSA-N n-hydroxypropanamide Chemical compound CCC(=O)NO RSIPQHOWTCNEBI-UHFFFAOYSA-N 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 150000007530 organic bases Chemical class 0.000 description 1
- 125000004043 oxo group Chemical group O=* 0.000 description 1
- GQYBCIHRWMPOOF-UHFFFAOYSA-N p-hydroxyphenylpyruvic acid Natural products OC(=O)C(O)=CC1=CC=C(O)C=C1 GQYBCIHRWMPOOF-UHFFFAOYSA-N 0.000 description 1
- 235000019319 peptone Nutrition 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- 159000000001 potassium salts Chemical class 0.000 description 1
- 125000001501 propionyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/872—Nocardia
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP50139405A JPS58876B2 (ja) | 1975-11-19 | 1975-11-19 | Ｆｒ −１９２３ ブツシツノ セイゾウホウホウ |
| NL7612667A NL7612667A (nl) | 1975-11-19 | 1976-11-15 | Werkwijze voor het bereiden van nocardicine a. |
| US05/742,013 US4110166A (en) | 1975-11-19 | 1976-11-15 | Process for the production of nocardicin A |
| AT851376A ATA851376A (de) | 1975-11-19 | 1976-11-16 | Verfahren zur herstellung von nocardicin a |
| BE172437A BE848430A (fr) | 1975-11-19 | 1976-11-17 | Procede pour la preparation de nocardicine a |
| AR265530A AR211940A1 (es) | 1975-11-19 | 1976-11-18 | Procedimiento para preparar nocardicina a |
| DK520676A DK520676A (da) | 1975-11-19 | 1976-11-18 | Fremgangsmade til fremstilling af nocardicin a |
| CA266,031A CA1067435A (en) | 1975-11-19 | 1976-11-18 | Process for the production of nocardicin a |
| FR7634795A FR2332324A1 (fr) | 1975-11-19 | 1976-11-18 | Procede pour la preparation de nocardicine a |
| DE19762652686 DE2652686A1 (de) | 1975-11-19 | 1976-11-19 | Verfahren zur herstellung nocardicin a |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP50139405A JPS58876B2 (ja) | 1975-11-19 | 1975-11-19 | Ｆｒ −１９２３ ブツシツノ セイゾウホウホウ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5264494A JPS5264494A (en) | 1977-05-27 |
| JPS58876B2 true JPS58876B2 (ja) | 1983-01-08 |
Family
ID=15244483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50139405A Expired JPS58876B2 (ja) | 1975-11-19 | 1975-11-19 | Ｆｒ −１９２３ ブツシツノ セイゾウホウホウ |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4110166A (OSRAM) |
| JP (1) | JPS58876B2 (OSRAM) |
| AR (1) | AR211940A1 (OSRAM) |
| AT (1) | ATA851376A (OSRAM) |
| BE (1) | BE848430A (OSRAM) |
| CA (1) | CA1067435A (OSRAM) |
| DE (1) | DE2652686A1 (OSRAM) |
| DK (1) | DK520676A (OSRAM) |
| FR (1) | FR2332324A1 (OSRAM) |
| NL (1) | NL7612667A (OSRAM) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6016236B2 (ja) * | 1977-11-18 | 1985-04-24 | 武田薬品工業株式会社 | 抗生物質ｃ―１５００３ ｐ―３の製造法 |
| JPS6010720B2 (ja) * | 1977-11-18 | 1985-03-19 | 武田薬品工業株式会社 | 抗生物質ｃ―１５００３ ｐ―４の製造法 |
| GB2046431B (en) * | 1979-04-12 | 1983-06-15 | Philips Electronic Associated | Pyroelectric detector protection circuit |
| US4212944A (en) * | 1979-06-04 | 1980-07-15 | Pfizer Inc. | Process for producing nocardicin A |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3923977A (en) * | 1972-08-29 | 1975-12-02 | Fujisawa Pharmaceutical Co | Antibiotic FR-1923 substance |
-
1975
- 1975-11-19 JP JP50139405A patent/JPS58876B2/ja not_active Expired
-
1976
- 1976-11-15 US US05/742,013 patent/US4110166A/en not_active Expired - Lifetime
- 1976-11-15 NL NL7612667A patent/NL7612667A/xx not_active Application Discontinuation
- 1976-11-16 AT AT851376A patent/ATA851376A/de not_active Application Discontinuation
- 1976-11-17 BE BE172437A patent/BE848430A/xx unknown
- 1976-11-18 CA CA266,031A patent/CA1067435A/en not_active Expired
- 1976-11-18 DK DK520676A patent/DK520676A/da unknown
- 1976-11-18 FR FR7634795A patent/FR2332324A1/fr active Granted
- 1976-11-18 AR AR265530A patent/AR211940A1/es active
- 1976-11-19 DE DE19762652686 patent/DE2652686A1/de active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2332324B1 (OSRAM) | 1978-12-29 |
| CA1067435A (en) | 1979-12-04 |
| NL7612667A (nl) | 1977-05-23 |
| US4110166A (en) | 1978-08-29 |
| ATA851376A (de) | 1979-02-15 |
| BE848430A (fr) | 1977-05-17 |
| AR211940A1 (es) | 1978-04-14 |
| DK520676A (da) | 1977-05-20 |
| DE2652686A1 (de) | 1977-06-02 |
| FR2332324A1 (fr) | 1977-06-17 |
| JPS5264494A (en) | 1977-05-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US3687926A (en) | Surfactin | |
| Salamon et al. | Aromatic Biosynthesis. IX. The Isolation of a Precursor of Shikimic Acid1 | |
| JP2873143B2 (ja) | 新規なアルキレンジアンモニウム ジクラブラネート誘導体、その製造方法並びにその使用 | |
| BE530983A (OSRAM) | ||
| FR2549836A1 (fr) | Procede de preparation du sel de sodium de cefuroxime | |
| US4786742A (en) | Crystalline lithium pseudomonete | |
| DE2216113C2 (de) | Verfahren zur Herstellung von Cephalosporinen | |
| JPS58876B2 (ja) | Ｆｒ −１９２３ ブツシツノ セイゾウホウホウ | |
| Kuroda et al. | FR-900130, A NOVEL AMINO ACID ANTIBIOTIC II. ISOLATION AND STRUCTURE ELUCIDATION OF THE ACETYL DERIVATIVE OF FR-900130 | |
| JPS6254433B2 (OSRAM) | ||
| KR880001354B1 (ko) | Ml-236b 유도체의 제조방법 | |
| US2885433A (en) | O-carbamyl-d-serine | |
| Taniguchi et al. | Isolation of Viridication form Penicillium crustosum, and Physiological Activity of Viridicatin and its 3-Carboxymethylene Derivative on Microorganisms and Plants | |
| CH382728A (fr) | Procédé de préparation de nouveaux composés de la série des tétracyclines | |
| JPH11228310A (ja) | 青枯れ病菌拮抗剤 | |
| US3975235A (en) | Process for the production of cephamycin type antibiotic substances | |
| US4587237A (en) | Mycotrienin-related compounds | |
| US3873529A (en) | Novel antibiotic ascofuranone and process for the production thereof | |
| JP3030896B2 (ja) | Ｗｂ９６８物質群およびその製造法 | |
| SU680657A3 (ru) | Способ получени антибиотика, обладающего антибактериальным действием против грамположительных бактерий | |
| Miyama et al. | D-malic acid production from DL-malic acid by enantiospecific assimilation with Acinetobacter lwofii | |
| US4353986A (en) | Process for producing antibiotic nanaomycin E | |
| JP2971204B2 (ja) | 新規物質ｗｋ−２９５５およびその製造法 | |
| CA1108078A (en) | Fermentation process | |
| SU544385A3 (ru) | Способ получени антибиотика 17.967 |