JPS585189A - 新規なアミドヒドロラ−ゼ - Google Patents

新規なアミドヒドロラ−ゼ

Info

Publication number
JPS585189A
JPS585189A JP56101161A JP10116181A JPS585189A JP S585189 A JPS585189 A JP S585189A JP 56101161 A JP56101161 A JP 56101161A JP 10116181 A JP10116181 A JP 10116181A JP S585189 A JPS585189 A JP S585189A
Authority
JP
Japan
Prior art keywords
antibiotic
enzyme
ability
solution
medium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56101161A
Other languages
English (en)
Japanese (ja)
Other versions
JPH038197B2 (OSRAM
Inventor
Katsuro Kubo
久保　克朗
Yasuo Fukagawa
泰男 深川
Tomoyuki Ishikura
石倉　知之
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanraku Inc
Sanraku Ocean Co Ltd
Original Assignee
Sanraku Inc
Sanraku Ocean Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanraku Inc, Sanraku Ocean Co Ltd filed Critical Sanraku Inc
Priority to JP56101161A priority Critical patent/JPS585189A/ja
Priority to DE8282105733T priority patent/DE3271129D1/de
Priority to EP82105733A priority patent/EP0068486B1/en
Priority to US06/394,169 priority patent/US4438201A/en
Publication of JPS585189A publication Critical patent/JPS585189A/ja
Publication of JPH038197B2 publication Critical patent/JPH038197B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
    • C12P17/184—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system containing a beta-lactam ring, e.g. thienamycin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
JP56101161A 1981-07-01 1981-07-01 新規なアミドヒドロラ−ゼ Granted JPS585189A (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP56101161A JPS585189A (ja) 1981-07-01 1981-07-01 新規なアミドヒドロラ−ゼ
DE8282105733T DE3271129D1 (de) 1981-07-01 1982-06-28 Novel amidohydrolase
EP82105733A EP0068486B1 (en) 1981-07-01 1982-06-28 Novel amidohydrolase
US06/394,169 US4438201A (en) 1981-07-01 1982-07-01 Amidohydrolase having ability to depantothenylate an antibiotic

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56101161A JPS585189A (ja) 1981-07-01 1981-07-01 新規なアミドヒドロラ−ゼ

Publications (2)

Publication Number Publication Date
JPS585189A true JPS585189A (ja) 1983-01-12
JPH038197B2 JPH038197B2 (OSRAM) 1991-02-05

Family

ID=14293315

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56101161A Granted JPS585189A (ja) 1981-07-01 1981-07-01 新規なアミドヒドロラ−ゼ

Country Status (4)

Country Link
US (1) US4438201A (OSRAM)
EP (1) EP0068486B1 (OSRAM)
JP (1) JPS585189A (OSRAM)
DE (1) DE3271129D1 (OSRAM)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3741723A1 (de) * 1987-12-09 1989-06-22 Uniroyal Englebert Gmbh Fahrzeugluftreifen
ATE439433T1 (de) * 1996-03-08 2009-08-15 Astellas Pharma Inc Prozess für die deacylierung von zyklischen lipopeptiden.
WO2000037486A1 (en) * 1998-12-22 2000-06-29 Holland Sweetener Company V.O.F. Synthesis and recovery of aspartame involving enzymatic deformylation step
US6617127B2 (en) 1998-12-22 2003-09-09 Holland Sweetener Company, V.O.F. Synthesis and recovery of aspartame involving enzymatic deformylation step
EP1013663A1 (en) * 1998-12-22 2000-06-28 Holland Sweetener Company V.O.F. Synthesis and recovery of aspartame involving enzymatic deformylation step
US9637746B2 (en) 2008-12-15 2017-05-02 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways
EP2379728A4 (en) * 2008-12-22 2016-04-13 Greenlight Biosciences Inc COMPOSITIONS AND METHODS FOR THE PRODUCTION OF A COMPOUND
WO2011140516A2 (en) 2010-05-07 2011-11-10 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways through enzyme relocation
KR101988063B1 (ko) 2010-08-31 2019-09-30 그린라이트 바이오사이언시스, 아이엔씨. 프로테아제 조작을 통한 대사 경로에서 유동의 제어 방법
KR20150010932A (ko) 2011-09-09 2015-01-29 그린라이트 바이오사이언시스, 아이엔씨. 카바페넴의 무세포 제조법
CA2919383A1 (en) 2013-08-05 2015-02-12 Greenlight Biosciences, Inc. Engineered proteins with a protease cleavage site
WO2016160936A1 (en) 2015-03-30 2016-10-06 Greenlight Biosciences, Inc. Cell-free production of ribonucleic acid
WO2017176963A1 (en) 2016-04-06 2017-10-12 Greenlight Biosciences, Inc. Cell-free production of ribonucleic acid
WO2019075167A1 (en) 2017-10-11 2019-04-18 Greenlight Biosciences, Inc. METHODS AND COMPOSITIONS FOR THE PRODUCTION OF NUCLEOSIDE TRIPHOSPHATE AND RIBONUCLEIC ACID

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4282322A (en) * 1975-11-24 1981-08-04 Merck & Co., Inc. Process for enzymatic deacylation of antibiotics
US4135978A (en) * 1977-08-19 1979-01-23 Merck & Co., Inc. Production of n-acyl-thienamycins
JPS5473788A (en) * 1977-11-17 1979-06-13 Sanraku Inc Antibiotic n-desacetyl ps-5
US4207395A (en) * 1978-11-02 1980-06-10 Merck & Co., Inc. Process for deacylating N-acyl-6-substituted-2-[2-aminoethylthio]-1-carbadethiapen-2-em-3-carboxylic acids

Also Published As

Publication number Publication date
EP0068486A3 (en) 1983-06-29
US4438201A (en) 1984-03-20
JPH038197B2 (OSRAM) 1991-02-05
EP0068486A2 (en) 1983-01-05
EP0068486B1 (en) 1986-05-14
DE3271129D1 (de) 1986-06-19

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