JPS58206533A - 活性型ビタミンｄ↓３誘導体組成物及びそれを活性成分とする薬剤 - Google Patents
活性型ビタミンｄ↓３誘導体組成物及びそれを活性成分とする薬剤Info
- Publication number
- JPS58206533A JPS58206533A JP8892382A JP8892382A JPS58206533A JP S58206533 A JPS58206533 A JP S58206533A JP 8892382 A JP8892382 A JP 8892382A JP 8892382 A JP8892382 A JP 8892382A JP S58206533 A JPS58206533 A JP S58206533A
- Authority
- JP
- Japan
- Prior art keywords
- composition
- formula
- active
- vitamin
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- 239000007789 gas Substances 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 229940075507 glyceryl monostearate Drugs 0.000 description 1
- 229940091561 guaiac Drugs 0.000 description 1
- 229960004337 hydroquinone Drugs 0.000 description 1
- 229910052816 inorganic phosphate Inorganic materials 0.000 description 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 229960003511 macrogol Drugs 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 229940041616 menthol Drugs 0.000 description 1
- LVWZTYCIRDMTEY-UHFFFAOYSA-N metamizole Chemical compound O=C1C(N(CS(O)(=O)=O)C)=C(C)N(C)N1C1=CC=CC=C1 LVWZTYCIRDMTEY-UHFFFAOYSA-N 0.000 description 1
- 229960002900 methylcellulose Drugs 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 239000001788 mono and diglycerides of fatty acids Substances 0.000 description 1
- PJUIMOJAAPLTRJ-UHFFFAOYSA-N monothioglycerol Chemical compound OCC(O)CS PJUIMOJAAPLTRJ-UHFFFAOYSA-N 0.000 description 1
- 125000002347 octyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 208000005368 osteomalacia Diseases 0.000 description 1
- 239000007800 oxidant agent Substances 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 230000000849 parathyroid Effects 0.000 description 1
- 239000000199 parathyroid hormone Substances 0.000 description 1
- 229960001319 parathyroid hormone Drugs 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- 229940068965 polysorbates Drugs 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 235000019422 polyvinyl alcohol Nutrition 0.000 description 1
- 229940088417 precipitated calcium carbonate Drugs 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- DOKHEARVIDLSFF-UHFFFAOYSA-N prop-1-en-1-ol Chemical group CC=CO DOKHEARVIDLSFF-UHFFFAOYSA-N 0.000 description 1
- TURAMGVWNUTQKH-UHFFFAOYSA-N propa-1,2-dien-1-one Chemical compound C=C=C=O TURAMGVWNUTQKH-UHFFFAOYSA-N 0.000 description 1
- JUJWROOIHBZHMG-UHFFFAOYSA-N pyridine Substances C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 1
- HNJBEVLQSNELDL-UHFFFAOYSA-N pyrrolidin-2-one Chemical compound O=C1CCCN1 HNJBEVLQSNELDL-UHFFFAOYSA-N 0.000 description 1
- 229940107700 pyruvic acid Drugs 0.000 description 1
- 230000009103 reabsorption Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 208000007442 rickets Diseases 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 235000010413 sodium alginate Nutrition 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 235000010267 sodium hydrogen sulphite Nutrition 0.000 description 1
- 235000010265 sodium sulphite Nutrition 0.000 description 1
- 239000007901 soft capsule Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 235000019303 thiodipropionic acid Nutrition 0.000 description 1
- 229940035024 thioglycerol Drugs 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 229960000984 tocofersolan Drugs 0.000 description 1
- 230000032258 transport Effects 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
- 239000002076 α-tocopherol Substances 0.000 description 1
- 235000004835 α-tocopherol Nutrition 0.000 description 1
- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8892382A JPS58206533A (ja) | 1982-05-27 | 1982-05-27 | 活性型ビタミンｄ↓３誘導体組成物及びそれを活性成分とする薬剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8892382A JPS58206533A (ja) | 1982-05-27 | 1982-05-27 | 活性型ビタミンｄ↓３誘導体組成物及びそれを活性成分とする薬剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS58206533A true JPS58206533A (ja) | 1983-12-01 |
| JPS6346728B2 JPS6346728B2 (enrdf_load_stackoverflow) | 1988-09-19 |
Family
ID=13956429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP8892382A Granted JPS58206533A (ja) | 1982-05-27 | 1982-05-27 | 活性型ビタミンｄ↓３誘導体組成物及びそれを活性成分とする薬剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS58206533A (enrdf_load_stackoverflow) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61151123A (ja) * | 1984-12-25 | 1986-07-09 | Sanwa Kagaku Kenkyusho:Kk | 安定化された３―オキシゲルミルプロピオン酸ポリマーを有効成分とする免疫調整剤 |
| JPH01146821A (ja) * | 1987-10-26 | 1989-06-08 | Eli Lilly & Co | ペルゴリド化合物の安定化 |
| WO1990003173A1 (en) | 1988-09-26 | 1990-04-05 | Teijin Limited | Stable aqueous preparation of active vitamin d¿3? |
| JPH02229115A (ja) * | 1989-03-01 | 1990-09-11 | Teijin Ltd | 安定性の改良された活性型ビタミンｄ↓３類固型製剤 |
| US5134240A (en) * | 1987-10-15 | 1992-07-28 | Hoffmann-Laroche, Inc. | Bicyclic peroxides |
| US5565442A (en) * | 1992-09-18 | 1996-10-15 | Teva Pharmaceutical Industries Ltd. | Stabilized pharmaceutical compositions containing derivatives of vitamins D2 and D3 |
| WO2001034147A1 (fr) * | 1999-11-11 | 2001-05-17 | Kyorin Pharmaceutical Co., Ltd. | Preparation solide orale |
| WO2018124260A1 (ja) * | 2016-12-28 | 2018-07-05 | 中外製薬株式会社 | Ｅｄ－７１の固体分散体および油分分散体を含む医薬組成物 |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997011703A1 (fr) * | 1995-09-28 | 1997-04-03 | Teijin Limited | Preventif ou remede contre l'hyperthyroidie |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2400819A1 (de) * | 1974-01-09 | 1975-07-17 | Bayer Ag | Verfahren zur herstellung fester zubereitungen von schwerloeslichen arzneimittelwirkstoffen in feinster verteilung |
| JPS5446837A (en) * | 1977-09-19 | 1979-04-13 | Kanebo Ltd | Easily absorbable nifedipin composition, its preparation, and anti-stenocardia containing the same |
| JPS5740414A (en) * | 1980-08-25 | 1982-03-06 | Teijin Ltd | Novel active type vitamin d3 derivative composition |
-
1982
- 1982-05-27 JP JP8892382A patent/JPS58206533A/ja active Granted
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2400819A1 (de) * | 1974-01-09 | 1975-07-17 | Bayer Ag | Verfahren zur herstellung fester zubereitungen von schwerloeslichen arzneimittelwirkstoffen in feinster verteilung |
| JPS5446837A (en) * | 1977-09-19 | 1979-04-13 | Kanebo Ltd | Easily absorbable nifedipin composition, its preparation, and anti-stenocardia containing the same |
| JPS5740414A (en) * | 1980-08-25 | 1982-03-06 | Teijin Ltd | Novel active type vitamin d3 derivative composition |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61151123A (ja) * | 1984-12-25 | 1986-07-09 | Sanwa Kagaku Kenkyusho:Kk | 安定化された３―オキシゲルミルプロピオン酸ポリマーを有効成分とする免疫調整剤 |
| US5134240A (en) * | 1987-10-15 | 1992-07-28 | Hoffmann-Laroche, Inc. | Bicyclic peroxides |
| JPH01146821A (ja) * | 1987-10-26 | 1989-06-08 | Eli Lilly & Co | ペルゴリド化合物の安定化 |
| WO1990003173A1 (en) | 1988-09-26 | 1990-04-05 | Teijin Limited | Stable aqueous preparation of active vitamin d¿3? |
| JPH02229115A (ja) * | 1989-03-01 | 1990-09-11 | Teijin Ltd | 安定性の改良された活性型ビタミンｄ↓３類固型製剤 |
| US5565442A (en) * | 1992-09-18 | 1996-10-15 | Teva Pharmaceutical Industries Ltd. | Stabilized pharmaceutical compositions containing derivatives of vitamins D2 and D3 |
| US5804573A (en) * | 1992-09-18 | 1998-09-08 | Teva Pharmaceutical Industries Ltd. | Stabilized pharmaceutical composition containing derivative of vitamins D2 and D3 |
| WO2001034147A1 (fr) * | 1999-11-11 | 2001-05-17 | Kyorin Pharmaceutical Co., Ltd. | Preparation solide orale |
| US7351429B1 (en) | 1999-11-11 | 2008-04-01 | Kyorin Pharmaceutical Co., Ltd. | Oral solid preparation |
| JP4610834B2 (ja) * | 1999-11-11 | 2011-01-12 | 杏林製薬株式会社 | 経口固形製剤 |
| WO2018124260A1 (ja) * | 2016-12-28 | 2018-07-05 | 中外製薬株式会社 | Ｅｄ－７１の固体分散体および油分分散体を含む医薬組成物 |
| JPWO2018124260A1 (ja) * | 2016-12-28 | 2019-10-31 | 中外製薬株式会社 | Ｅｄ−７１の固体分散体および油分分散体を含む医薬組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6346728B2 (enrdf_load_stackoverflow) | 1988-09-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EXPY | Cancellation because of completion of term | ||
| R154 | Certificate of patent or utility model (reissue) |
Free format text: JAPANESE INTERMEDIATE CODE: R154 |