JPS5813515A - 抗アルドステロン活性ステロイド誘導体 - Google Patents

抗アルドステロン活性ステロイド誘導体

Info

Publication number
JPS5813515A
JPS5813515A JP56112633A JP11263381A JPS5813515A JP S5813515 A JPS5813515 A JP S5813515A JP 56112633 A JP56112633 A JP 56112633A JP 11263381 A JP11263381 A JP 11263381A JP S5813515 A JPS5813515 A JP S5813515A
Authority
JP
Japan
Prior art keywords
compound
formula
acid
ethyl acetate
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP56112633A
Other languages
English (en)
Japanese (ja)
Inventor
Susumu Kamata
進 鎌田
Wataru Nagata
永田 亘
Eiji Kondo
栄二 近藤
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Priority to JP56112633A priority Critical patent/JPS5813515A/ja
Priority to NL8202832A priority patent/NL8202832A/nl
Priority to DE19823226322 priority patent/DE3226322A1/de
Priority to FR8212514A priority patent/FR2510584A1/fr
Priority to GB08220647A priority patent/GB2102003A/en
Publication of JPS5813515A publication Critical patent/JPS5813515A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP56112633A 1981-07-17 1981-07-17 抗アルドステロン活性ステロイド誘導体 Pending JPS5813515A (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP56112633A JPS5813515A (ja) 1981-07-17 1981-07-17 抗アルドステロン活性ステロイド誘導体
NL8202832A NL8202832A (nl) 1981-07-17 1982-07-13 Steroiden met anti-aldosteronwerking.
DE19823226322 DE3226322A1 (de) 1981-07-17 1982-07-14 11ss,18-oxido-steroide und verfahren zu ihrer herstellung
FR8212514A FR2510584A1 (de) 1981-07-17 1982-07-16
GB08220647A GB2102003A (en) 1981-07-17 1982-07-16 New 11 beta ,18-epoxy steroids having anti-aldosterone activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56112633A JPS5813515A (ja) 1981-07-17 1981-07-17 抗アルドステロン活性ステロイド誘導体

Publications (1)

Publication Number Publication Date
JPS5813515A true JPS5813515A (ja) 1983-01-26

Family

ID=14591607

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56112633A Pending JPS5813515A (ja) 1981-07-17 1981-07-17 抗アルドステロン活性ステロイド誘導体

Country Status (5)

Country Link
JP (1) JPS5813515A (de)
DE (1) DE3226322A1 (de)
FR (1) FR2510584A1 (de)
GB (1) GB2102003A (de)
NL (1) NL8202832A (de)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8049858B2 (en) 2005-07-11 2011-11-01 Fujitsu Limited Liquid crystal display element
US8139196B2 (en) 2006-09-29 2012-03-20 Fujitsu Limited Liquid crystal display element, method of manufacturing the element, and electronic paper having the element
US8363200B2 (en) 2006-08-23 2013-01-29 Fujitsu Limited Display element, electronic paper using the element, and electronic terminal using the element

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4081538A (en) * 1976-12-02 1978-03-28 Stanley Ulick Aldosterone antagonists
US4104271A (en) * 1977-06-13 1978-08-01 G. D. Searle & Co. 11β,18-EPOXY-9α-HALO-17,18-DIHYDROXY-3-OXO-17α-PREGN-4-ENE-21-CARBOXYLIC ACID γ-LACTONES AND CONGENERS

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8049858B2 (en) 2005-07-11 2011-11-01 Fujitsu Limited Liquid crystal display element
US8363200B2 (en) 2006-08-23 2013-01-29 Fujitsu Limited Display element, electronic paper using the element, and electronic terminal using the element
US8139196B2 (en) 2006-09-29 2012-03-20 Fujitsu Limited Liquid crystal display element, method of manufacturing the element, and electronic paper having the element

Also Published As

Publication number Publication date
DE3226322A1 (de) 1983-02-03
NL8202832A (nl) 1983-02-16
GB2102003A (en) 1983-01-26
FR2510584A1 (de) 1983-02-04

Similar Documents

Publication Publication Date Title
Partridge et al. Vitamin D3 Metabolites I. Synthesis of 25‐hydroxycholesterol
CH647222A5 (de) 9-desoxy-9a-methylen-isostere von pgi-2 und verfahren zu deren herstellung.
JP2001505207A (ja) アミノステロール、ビタミンd類似体および他の化合物の製造に有用な24−ヒドロキシル化された化合物の立体選択的合成
JPS59139400A (ja) 抗アルドステロン活性ステロイド誘導体
FR2569408A1 (fr) Nouveaux steroides substitues en position 10 par un radical comportant une double ou triple liaison, leur procede de preparation, leur application comme medicaments, les compositions pharmaceutiques les renfermant
JP3037427B2 (ja) カルシトリオールならびにその誘導体を製造するための原料化合物、これらの原料化合物の製造方法ならびにこの方法のための中間体
JPS5813515A (ja) 抗アルドステロン活性ステロイド誘導体
Oliveto et al. The Formation of Ketals from Steroid Ketones with Selenium Dioxide and Methanol
Weisenborn et al. The Structure of Isorubijervine. Conversion to Solanidane and Solanidane-3β-ol1
JPH0635475B2 (ja) 1α,3β,25−トリヒドロキシ−24−ホモコレスタ−5,22−ジエン化合物
DE1643948A1 (de) Verfahren zur Herstellung von Acetylenverbindungen
Heathcock et al. Photochemistry of 1, 6-cyclodecadienes. II. Synthesis and photochemistry of 6-methyl-1, 6-cyclodecadien-3-one
JPH0565293A (ja) 心臓血管系に作用するステロイド化合物およびそれを含む薬剤
EP0044575B1 (de) Zwischenprodukte in der Herstellung von 2-substituierten 19-nor-Steroiden
SATO et al. The Chemistry of the Spiroaminoketal Side Chain of Solasodine and Tomatidine. II. 1 Chemistry of 3β, 16β-Diacetoxy-20-(2'-Δ2'-N-acetyl-5'-methyltetrahydropyridyl)-5-pregnene
JPS63258487A (ja) 17α−エチニル−17β−ヒドロキシ−18−メチル−4,15−エストラジエン−3−オンの製造方法、及びこの方法の中間生成物
Arth et al. Approaches to the Total Synthesis of Adrenal Steroids. XIII. Formation and Reaction of Racemic 16, 20-Diketosteroids
Wolff et al. The Synthesis of C-18 Functionalized Hormone Analogs. III. Synthesis of Aldosterone1a
JPS643880B2 (de)
JPS581000A (ja) 4α,5α−エポキシ−3,20−ジオキソプレグナン−2α,16α−ジカルボニトリル,その製造法およびそれを含む製薬学的組成物
FR2558828A1 (fr) " 1a,25-dihydroxy-22z-deshydrovitamine d " composition pharmaceutique et procede de preparation
FR2496669A1 (fr) Nouveaux derives steroides 3-ceto4 ou1-4 substitues en position 7, leur procede de preparation et leur application comme medicaments
Yoshioka et al. Tetraneurin-E and-F. New C-15 oxygenated pseudoguaianolides from Parthenium (Compositae)
DE2129943A1 (de) 19-Nor-6,6-aethylen-20-spiroxene
JP2642189B2 (ja) ステロイド誘導体及びその製造方法