JPS5793953A - Novel preparation of pantethine - Google Patents

Info

Publication number

JPS5793953A

JPS5793953A JP16969780A JP16969780A JPS5793953A JP S5793953 A JPS5793953 A JP S5793953A JP 16969780 A JP16969780 A JP 16969780A JP 16969780 A JP16969780 A JP 16969780A JP S5793953 A JPS5793953 A JP S5793953A

Authority

JP

Japan

Prior art keywords

salt

pantethine

aluminum chloride

ferric chloride

cystamine

Prior art date

1980-12-03

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
• Discuss

• DJWYOLJPSHDSAL-UHFFFAOYSA-N Pantethine Natural products OCC(C)(C)C(O)C(=O)NCCC(=O)NCCSSCCNC(=O)CCNC(=O)C(O)C(C)(C)CO DJWYOLJPSHDSAL-UHFFFAOYSA-N 0.000 title abstract 3
• 235000008975 pantethine Nutrition 0.000 title abstract 3
• 239000011581 pantethine Substances 0.000 title abstract 3
• DJWYOLJPSHDSAL-ROUUACIJSA-N pantethine Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSSCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)CO DJWYOLJPSHDSAL-ROUUACIJSA-N 0.000 title abstract 3
• 229960000903 pantethine Drugs 0.000 title abstract 3
• VSCWAEJMTAWNJL-UHFFFAOYSA-K aluminium trichloride Chemical compound Cl[Al](Cl)Cl VSCWAEJMTAWNJL-UHFFFAOYSA-K 0.000 abstract 6
• GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 abstract 4
• 150000003839 salts Chemical class 0.000 abstract 4
• 229910021578 Iron(III) chloride Inorganic materials 0.000 abstract 3
• ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
• RBTARNINKXHZNM-UHFFFAOYSA-K iron trichloride Chemical compound Cl[Fe](Cl)Cl RBTARNINKXHZNM-UHFFFAOYSA-K 0.000 abstract 3
• GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 abstract 2
• JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
• 150000001718 carbodiimides Chemical class 0.000 abstract 2
• 239000003054 catalyst Substances 0.000 abstract 2
• OOTFVKOQINZBBF-UHFFFAOYSA-N cystamine Chemical compound CCSSCCN OOTFVKOQINZBBF-UHFFFAOYSA-N 0.000 abstract 2
• 229940099500 cystamine Drugs 0.000 abstract 2
• 235000019161 pantothenic acid Nutrition 0.000 abstract 2
• 239000011713 pantothenic acid Substances 0.000 abstract 2
• 229940055726 pantothenic acid Drugs 0.000 abstract 2
• 239000002904 solvent Substances 0.000 abstract 2
• NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 1
• 238000006482 condensation reaction Methods 0.000 abstract 1
• 229940079593 drug Drugs 0.000 abstract 1
• 239000003814 drug Substances 0.000 abstract 1
• -1 e.g. Substances 0.000 abstract 1
• 239000003456 ion exchange resin Substances 0.000 abstract 1
• 229920003303 ion-exchange polymer Polymers 0.000 abstract 1
• 229920000642 polymer Polymers 0.000 abstract 1
• UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
• 239000002994 raw material Substances 0.000 abstract 1
• 239000000126 substance Substances 0.000 abstract 1