JPS5759887A - Production of dibenzothiepinpropionamide derivative - Google Patents

Production of dibenzothiepinpropionamide derivative

Info

Publication number
JPS5759887A
JPS5759887A JP13448180A JP13448180A JPS5759887A JP S5759887 A JPS5759887 A JP S5759887A JP 13448180 A JP13448180 A JP 13448180A JP 13448180 A JP13448180 A JP 13448180A JP S5759887 A JPS5759887 A JP S5759887A
Authority
JP
Japan
Prior art keywords
condensing agent
compound
derivative
dibenzothiepinpropionamide
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP13448180A
Other languages
Japanese (ja)
Other versions
JPS6363543B2 (en
Inventor
Mitsuo Mazaki
Toru Yamanaka
Shigeo Ikeda
Yasuo Kishi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Chemiphar Co Ltd
Original Assignee
Nippon Chemiphar Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Chemiphar Co Ltd filed Critical Nippon Chemiphar Co Ltd
Priority to JP13448180A priority Critical patent/JPS5759887A/en
Priority to CA366,875A priority patent/CA1127652A/en
Priority to NL8006846A priority patent/NL8006846A/en
Priority to BE0/203218A priority patent/BE886731A/en
Publication of JPS5759887A publication Critical patent/JPS5759887A/en
Publication of JPS6363543B2 publication Critical patent/JPS6363543B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D337/14—[b,f]-condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: The cyclization reaction of a phenylacetic ester derivative is effected using a condensing agent to produce the titled compound through the one-stage process with industrial advantage, which is used as an anti-inflammatory or analgesic or an intermediate thereof.
CONSTITUTION: The cyclization reaction of a phenylacetic ester derivative of formula II (R is lower alkyl) is conducted in the presence of a condensing agent such as polyphosphoric acid or polyphosphoric estr at 50W150°C to give the compound of formulaI. The amount of the condensing agent is 5W30 times, preferably 10W20 times the weight amount of the compound of formula II.
COPYRIGHT: (C)1982,JPO&Japio
JP13448180A 1980-09-29 1980-09-29 Production of dibenzothiepinpropionamide derivative Granted JPS5759887A (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP13448180A JPS5759887A (en) 1980-09-29 1980-09-29 Production of dibenzothiepinpropionamide derivative
CA366,875A CA1127652A (en) 1980-09-29 1980-12-16 Process for producing dibenzothiepin propionamide derivatives
NL8006846A NL8006846A (en) 1980-09-29 1980-12-17 PROCESS FOR PREPARING DIBENZOTHIEPIEN PROPIONAMID DERIVATIVES.
BE0/203218A BE886731A (en) 1980-09-29 1980-12-18 PROCESS FOR THE PREPARATION OF DIBENZOTHIEPINE-PROPIONAMIDE DERIVATIVES

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13448180A JPS5759887A (en) 1980-09-29 1980-09-29 Production of dibenzothiepinpropionamide derivative

Publications (2)

Publication Number Publication Date
JPS5759887A true JPS5759887A (en) 1982-04-10
JPS6363543B2 JPS6363543B2 (en) 1988-12-07

Family

ID=15129326

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13448180A Granted JPS5759887A (en) 1980-09-29 1980-09-29 Production of dibenzothiepinpropionamide derivative

Country Status (4)

Country Link
JP (1) JPS5759887A (en)
BE (1) BE886731A (en)
CA (1) CA1127652A (en)
NL (1) NL8006846A (en)

Also Published As

Publication number Publication date
NL8006846A (en) 1982-04-16
CA1127652A (en) 1982-07-13
BE886731A (en) 1981-04-16
JPS6363543B2 (en) 1988-12-07

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