JPS5732277A - 5,6,7-trinor-4,8-inter-m-phenylene pgi2 derivative - Google Patents
5,6,7-trinor-4,8-inter-m-phenylene pgi2 derivativeInfo
- Publication number
- JPS5732277A JPS5732277A JP10675180A JP10675180A JPS5732277A JP S5732277 A JPS5732277 A JP S5732277A JP 10675180 A JP10675180 A JP 10675180A JP 10675180 A JP10675180 A JP 10675180A JP S5732277 A JPS5732277 A JP S5732277A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- group
- activity
- trinor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 abstract 6
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- 230000029936 alkylation Effects 0.000 abstract 1
- 238000005804 alkylation reaction Methods 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003435 aroyl group Chemical group 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 230000015271 coagulation Effects 0.000 abstract 1
- 238000005345 coagulation Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
- 125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 1
- 210000004051 gastric juice Anatomy 0.000 abstract 1
- 210000001156 gastric mucosa Anatomy 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical group O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000001766 physiological effect Effects 0.000 abstract 1
- 230000002633 protecting effect Effects 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
- 125000001412 tetrahydropyranyl group Chemical group 0.000 abstract 1
- -1 β-naphthyl Chemical group 0.000 abstract 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Furan Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10675180A JPS5732277A (en) | 1980-08-05 | 1980-08-05 | 5,6,7-trinor-4,8-inter-m-phenylene pgi2 derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10675180A JPS5732277A (en) | 1980-08-05 | 1980-08-05 | 5,6,7-trinor-4,8-inter-m-phenylene pgi2 derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5732277A true JPS5732277A (en) | 1982-02-20 |
JPH0212226B2 JPH0212226B2 (enrdf_load_stackoverflow) | 1990-03-19 |
Family
ID=14441611
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10675180A Granted JPS5732277A (en) | 1980-08-05 | 1980-08-05 | 5,6,7-trinor-4,8-inter-m-phenylene pgi2 derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5732277A (enrdf_load_stackoverflow) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57144276A (en) * | 1981-03-03 | 1982-09-06 | Toray Ind Inc | 5,6,7-trinor-4,8-inter-m-phenylene pgi2 derivative |
JPS59161371A (ja) * | 1983-03-04 | 1984-09-12 | Toray Ind Inc | (−)−〔7−ブロモ−3a,8b−シス−ジヒドロ−3H−シクロペンタ〔b〕ベンゾフラン−5−イル〕ギ酸の製造法 |
JPS60148633A (ja) * | 1984-01-13 | 1985-08-05 | Nippon Denso Co Ltd | ホ−ス接続金具用金属スリ−ブの製造方法 |
JPH0662599B1 (enrdf_load_stackoverflow) * | 1987-10-16 | 1994-08-17 | Toray Industries | |
US5401768A (en) * | 1987-10-16 | 1995-03-28 | Toray Industries, Inc. | 2,5,6,7-tetranor-4,8-inter-m-phenylene PGI2, derivative, manufacturing process thereof and its use |
US6340693B1 (en) * | 1997-03-14 | 2002-01-22 | Toray Industries, Inc. | Protective agent for nervous system structural cells |
EP1201235A4 (en) * | 1999-08-05 | 2003-07-09 | Teijin Ltd | AGENTS FOR IMPROVING THE NEUROPATHY THAT CONTAINS NITROGEN COMPOUNDS AS AN ACTIVE SUBSTANCE |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999033470A1 (fr) * | 1997-12-25 | 1999-07-08 | Toray Industries, Inc. | ANTI $i(HELICOBACTER PYLORI) |
US20030092760A1 (en) | 2001-03-12 | 2003-05-15 | Toray Industries, Inc. | Therapeutic agent for renal failure |
-
1980
- 1980-08-05 JP JP10675180A patent/JPS5732277A/ja active Granted
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57144276A (en) * | 1981-03-03 | 1982-09-06 | Toray Ind Inc | 5,6,7-trinor-4,8-inter-m-phenylene pgi2 derivative |
JPS59161371A (ja) * | 1983-03-04 | 1984-09-12 | Toray Ind Inc | (−)−〔7−ブロモ−3a,8b−シス−ジヒドロ−3H−シクロペンタ〔b〕ベンゾフラン−5−イル〕ギ酸の製造法 |
JPS60148633A (ja) * | 1984-01-13 | 1985-08-05 | Nippon Denso Co Ltd | ホ−ス接続金具用金属スリ−ブの製造方法 |
JPH0662599B1 (enrdf_load_stackoverflow) * | 1987-10-16 | 1994-08-17 | Toray Industries | |
US5401768A (en) * | 1987-10-16 | 1995-03-28 | Toray Industries, Inc. | 2,5,6,7-tetranor-4,8-inter-m-phenylene PGI2, derivative, manufacturing process thereof and its use |
US6340693B1 (en) * | 1997-03-14 | 2002-01-22 | Toray Industries, Inc. | Protective agent for nervous system structural cells |
EP1201235A4 (en) * | 1999-08-05 | 2003-07-09 | Teijin Ltd | AGENTS FOR IMPROVING THE NEUROPATHY THAT CONTAINS NITROGEN COMPOUNDS AS AN ACTIVE SUBSTANCE |
Also Published As
Publication number | Publication date |
---|---|
JPH0212226B2 (enrdf_load_stackoverflow) | 1990-03-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS57131791A (en) | Benzodiazepine derivative and its preparation | |
IL77396A (en) | Pharmaceutical compositions containing bicyclic heteroarylpiperazine derivatives,certain such novel compounds and their preparation | |
JPS5636477A (en) | 5,6,7-trinor-4,8-inter-m-phenylene pgi2 derivative | |
JPS5732277A (en) | 5,6,7-trinor-4,8-inter-m-phenylene pgi2 derivative | |
JPS5461194A (en) | Preparation of n22substituted 2*66diaminonebularin | |
JPS57176982A (en) | Dioxolanylazetidinone compound, its preparation and use | |
JPS57192339A (en) | Isoprenylamine derivative | |
JPS5750935A (en) | 1,4-benzoquinone derivative | |
JPS5746977A (en) | Novel prostacyclin and its preparation | |
JPS57165382A (en) | Fluoro-pgi2 compound and its preparation | |
JPS57192340A (en) | Isoprenylamine derivative | |
EP0124252A3 (en) | Double ester of 16beta-ethylestran-17beta-ol derivatives | |
JPS565456A (en) | Prostacycline derivative | |
JPS5745173A (en) | Hydroxy-delta-lactone and its preparation | |
JPS57171965A (en) | Novel prostaglandin intermediate and its preparation | |
JPS5618935A (en) | Novel bicyclo-octane derivative and its preparation | |
JPS5795980A (en) | 7-hydroxy pgi2 and its preparation | |
JPS57158709A (en) | Vermin attractant | |
JPS56122372A (en) | Prostaglandin i2 derivative | |
JPS5699480A (en) | Preparation of pyridopyrimidine derivative | |
JPS55153739A (en) | Quinone compound and its preparation | |
JPS57200378A (en) | Halogenated pgi2 and its preparation | |
JPS53119819A (en) | Substituted iso-valerianic acid and its ester | |
JPS57212137A (en) | Preparation of phenyl aliphtic acid derivative | |
JPS55145700A (en) | 25-hydroxy-24-oxo-5beta-cholestane derivative and its preparation |