JPS55153739A - Quinone compound and its preparation - Google Patents

Quinone compound and its preparation

Info

Publication number
JPS55153739A
JPS55153739A JP6191579A JP6191579A JPS55153739A JP S55153739 A JPS55153739 A JP S55153739A JP 6191579 A JP6191579 A JP 6191579A JP 6191579 A JP6191579 A JP 6191579A JP S55153739 A JPS55153739 A JP S55153739A
Authority
JP
Japan
Prior art keywords
compound
formula
acid ester
quinone compound
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP6191579A
Other languages
Japanese (ja)
Other versions
JPS627900B2 (en
Inventor
Shinji Terao
Mitsuru Shiraishi
Kaneyoshi Katou
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to JP6191579A priority Critical patent/JPS55153739A/en
Publication of JPS55153739A publication Critical patent/JPS55153739A/en
Priority to US06/471,457 priority patent/US4533554A/en
Publication of JPS627900B2 publication Critical patent/JPS627900B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:Quinone compound and the corresponding hydroquinone compound of formula I [n is 2W10; R1 is methyl, methoxy, or two R1s together form -CH=CH-CH=CH-; R2 is H, lower alkyl, or formula II (m is 1W10)].
EXAMPLE: Quinonecarboxylic acid ester.
USE: Medicines, e.g. hypotensives, lenitives, antiulcers, anti-inflammatory agents, diuretics, antithrombotics, cerebral circulation improving agents, and their intermediates, having low toxicity, activity of regulating prostaglandin biosynthesis and effect to block adrenergic activity responce.
PROCESS: The compound of formula I is obtained by the reaction of the compound of formula III or IV (R3 is protecting group) with orthoacetic acid ester.
COPYRIGHT: (C)1980,JPO&Japio
JP6191579A 1979-05-18 1979-05-18 Quinone compound and its preparation Granted JPS55153739A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP6191579A JPS55153739A (en) 1979-05-18 1979-05-18 Quinone compound and its preparation
US06/471,457 US4533554A (en) 1979-05-18 1983-03-02 Quinone derivatives and use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6191579A JPS55153739A (en) 1979-05-18 1979-05-18 Quinone compound and its preparation

Publications (2)

Publication Number Publication Date
JPS55153739A true JPS55153739A (en) 1980-11-29
JPS627900B2 JPS627900B2 (en) 1987-02-19

Family

ID=13184925

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6191579A Granted JPS55153739A (en) 1979-05-18 1979-05-18 Quinone compound and its preparation

Country Status (1)

Country Link
JP (1) JPS55153739A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997049662A1 (en) * 1996-06-25 1997-12-31 The University Of Sheffield Quinone bacterial inhibitors
GB2476643A (en) * 2009-12-23 2011-07-06 Haomamedica Ltd 1,4-Dihydro-1,4-dioxonaphtalene derivatives as anticoagulants
US9622989B2 (en) 2009-12-23 2017-04-18 Haoma Medica Limited Treatment of osteoporosis

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997049662A1 (en) * 1996-06-25 1997-12-31 The University Of Sheffield Quinone bacterial inhibitors
GB2476643A (en) * 2009-12-23 2011-07-06 Haomamedica Ltd 1,4-Dihydro-1,4-dioxonaphtalene derivatives as anticoagulants
GB2476643B (en) * 2009-12-23 2012-11-14 Haomamedica Ltd 1,4-Dihydro-1,4-dioxonaphtalene derivatives as anticoagulants
AU2010334565B2 (en) * 2009-12-23 2016-10-06 Haomamedica Limited Anticoagulant compounds and their use
US9622989B2 (en) 2009-12-23 2017-04-18 Haoma Medica Limited Treatment of osteoporosis

Also Published As

Publication number Publication date
JPS627900B2 (en) 1987-02-19

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