JPS57183761A - Carbostyril derivative - Google Patents
Carbostyril derivativeInfo
- Publication number
- JPS57183761A JPS57183761A JP56066730A JP6673081A JPS57183761A JP S57183761 A JPS57183761 A JP S57183761A JP 56066730 A JP56066730 A JP 56066730A JP 6673081 A JP6673081 A JP 6673081A JP S57183761 A JPS57183761 A JP S57183761A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- carbostyril
- cerebral
- formulai
- cycloalkylalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical class C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 230000002490 cerebral effect Effects 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- -1 3-[4-(1-Cyclohexyltetrazole-5-yl) butoxy]carbostyril Chemical compound 0.000 abstract 1
- 206010008190 Cerebrovascular accident Diseases 0.000 abstract 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 229940099471 Phosphodiesterase inhibitor Drugs 0.000 abstract 1
- BERPCVULMUPOER-UHFFFAOYSA-N Quinolinediol Chemical class C1=CC=C2NC(=O)C(O)=CC2=C1 BERPCVULMUPOER-UHFFFAOYSA-N 0.000 abstract 1
- 208000006011 Stroke Diseases 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 125000005041 acyloxyalkyl group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 230000000747 cardiac effect Effects 0.000 abstract 1
- 206010008118 cerebral infarction Diseases 0.000 abstract 1
- 238000006704 dehydrohalogenation reaction Methods 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 208000010125 myocardial infarction Diseases 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 1
- 239000002571 phosphodiesterase inhibitor Substances 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
Landscapes
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56066730A JPS57183761A (en) | 1981-04-30 | 1981-04-30 | Carbostyril derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56066730A JPS57183761A (en) | 1981-04-30 | 1981-04-30 | Carbostyril derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS57183761A true JPS57183761A (en) | 1982-11-12 |
| JPH0114911B2 JPH0114911B2 (enrdf_load_stackoverflow) | 1989-03-14 |
Family
ID=13324293
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP56066730A Granted JPS57183761A (en) | 1981-04-30 | 1981-04-30 | Carbostyril derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS57183761A (enrdf_load_stackoverflow) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62135423A (ja) * | 1985-12-09 | 1987-06-18 | Otsuka Pharmaceut Co Ltd | 低酸素症改善剤 |
| JPS6345220A (ja) * | 1986-04-02 | 1988-02-26 | Otsuka Pharmaceut Co Ltd | 血小板粘着抑制剤 |
| JPS646271A (en) * | 1986-04-02 | 1989-01-10 | Otsuka Pharma Co Ltd | Carbostyril derivative |
| WO1989010919A1 (en) | 1988-05-02 | 1989-11-16 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
| US5597922A (en) * | 1994-07-29 | 1997-01-28 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon | Glycine receptor antagonist pharmacophore |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS52125163A (en) * | 1976-04-14 | 1977-10-20 | Otsuka Pharmaceut Co Ltd | Novel benzcyclamide derivatives |
| JPS5430179A (en) * | 1977-08-10 | 1979-03-06 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
| JPS54115383A (en) * | 1978-02-28 | 1979-09-07 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
| JPS54163825A (en) * | 1978-06-15 | 1979-12-26 | Otsuka Pharma Co Ltd | Phosphoesterase inhibitor |
| JPS5535019A (en) * | 1978-09-01 | 1980-03-11 | Otsuka Pharmaceut Co Ltd | Carbostyryl derivative |
| JPS5579370A (en) * | 1978-12-08 | 1980-06-14 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
-
1981
- 1981-04-30 JP JP56066730A patent/JPS57183761A/ja active Granted
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS52125163A (en) * | 1976-04-14 | 1977-10-20 | Otsuka Pharmaceut Co Ltd | Novel benzcyclamide derivatives |
| JPS5430179A (en) * | 1977-08-10 | 1979-03-06 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
| JPS54115383A (en) * | 1978-02-28 | 1979-09-07 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
| JPS54163825A (en) * | 1978-06-15 | 1979-12-26 | Otsuka Pharma Co Ltd | Phosphoesterase inhibitor |
| JPS5535019A (en) * | 1978-09-01 | 1980-03-11 | Otsuka Pharmaceut Co Ltd | Carbostyryl derivative |
| JPS5579370A (en) * | 1978-12-08 | 1980-06-14 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62135423A (ja) * | 1985-12-09 | 1987-06-18 | Otsuka Pharmaceut Co Ltd | 低酸素症改善剤 |
| JPS6345220A (ja) * | 1986-04-02 | 1988-02-26 | Otsuka Pharmaceut Co Ltd | 血小板粘着抑制剤 |
| JPS646271A (en) * | 1986-04-02 | 1989-01-10 | Otsuka Pharma Co Ltd | Carbostyril derivative |
| WO1989010919A1 (en) | 1988-05-02 | 1989-11-16 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
| US5597922A (en) * | 1994-07-29 | 1997-01-28 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon | Glycine receptor antagonist pharmacophore |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0114911B2 (enrdf_load_stackoverflow) | 1989-03-14 |
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