JPS57145827A - Optical resolution of allethrolone - Google Patents
Optical resolution of allethroloneInfo
- Publication number
- JPS57145827A JPS57145827A JP3124781A JP3124781A JPS57145827A JP S57145827 A JPS57145827 A JP S57145827A JP 3124781 A JP3124781 A JP 3124781A JP 3124781 A JP3124781 A JP 3124781A JP S57145827 A JPS57145827 A JP S57145827A
- Authority
- JP
- Japan
- Prior art keywords
- allethrolone
- optically active
- acid
- ester
- optical resolution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: To prepare optically active allethrolone useful as a low-toxic insecticide, in high purity and yield, by the optical resolution of allethrolone using an optically active trans-2-bezamidocyclohexanecarboxylic acid as the optical resolution agent.
CONSTITUTION: Optically active trans-2-benzamidocyclohexanecarboxylic acid or its reactive drerivative is made to react with an acid-chlorinating agent (e.g. SOCl2) to obtain the acid chloride of the optically active carboxilic acid, which is dissolved together with optically impure allethrolone in an inert organic solvent. A pyridine base, etc. is added dropwise to the solution, and the resultant crystalline diastereomer ester is separated into the ester of (+)-allethrolone and the ester of (-)-allethrolone by fractional crystallization. After optical resolution, the ester is hydrolyzed at 0°C in water or in a water-containing solvent in the presence or absence of a base to afford optically active allethrolone.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3124781A JPS57145827A (en) | 1981-03-06 | 1981-03-06 | Optical resolution of allethrolone |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3124781A JPS57145827A (en) | 1981-03-06 | 1981-03-06 | Optical resolution of allethrolone |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57145827A true JPS57145827A (en) | 1982-09-09 |
JPS6345653B2 JPS6345653B2 (en) | 1988-09-12 |
Family
ID=12326037
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP3124781A Granted JPS57145827A (en) | 1981-03-06 | 1981-03-06 | Optical resolution of allethrolone |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57145827A (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0289965U (en) * | 1988-12-28 | 1990-07-17 |
-
1981
- 1981-03-06 JP JP3124781A patent/JPS57145827A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS6345653B2 (en) | 1988-09-12 |
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