JPS5585547A - Preparation of substituted phenylacetic acid - Google Patents

Preparation of substituted phenylacetic acid

Info

Publication number
JPS5585547A
JPS5585547A JP16212578A JP16212578A JPS5585547A JP S5585547 A JPS5585547 A JP S5585547A JP 16212578 A JP16212578 A JP 16212578A JP 16212578 A JP16212578 A JP 16212578A JP S5585547 A JPS5585547 A JP S5585547A
Authority
JP
Japan
Prior art keywords
compound
formula
high yield
alkali
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP16212578A
Other languages
Japanese (ja)
Other versions
JPS565730B2 (en
Inventor
Yukio Fujimori
Takumi Matsumura
Akihiko Nakayama
Hiroshi Kawahara
Katsuya Tani
Hiroyuki Kondo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daito Koeki KK
Original Assignee
Daito Koeki KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daito Koeki KK filed Critical Daito Koeki KK
Priority to JP16212578A priority Critical patent/JPS5585547A/en
Publication of JPS5585547A publication Critical patent/JPS5585547A/en
Publication of JPS565730B2 publication Critical patent/JPS565730B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: To obtain the high purity title compound, useful as an antiphlogistic, an analgesic and an antipyretic, in high yield in a simple process, by reacting a derivative of N-substituted-3-alkoxycarbonyl-3,4-epoxy-2-quinolinonimine novel compound with a base.
CONSTITUTION: A novel compound of formula III (R=lower alkyl) is oxidized e.g. with hydrogen peroxide in the presence of sodium tungstate or with acetonitrile and hydrogen peroxide in the presence of an alkali hydroxide to give a novel compound of formula I. The compound obtained is treated with an alkali, preferably alkali metal hydroxide, carbonate or bicarbonate, or with an alkaline earth metal hydroxide to afford the high purity title compound of formula II in high yield. The starting compound of formula III can be obtained easily in high yield by the condensation of a compound of formula IV and a compound of formula V.
COPYRIGHT: (C)1980,JPO&Japio
JP16212578A 1978-12-25 1978-12-25 Preparation of substituted phenylacetic acid Granted JPS5585547A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16212578A JPS5585547A (en) 1978-12-25 1978-12-25 Preparation of substituted phenylacetic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16212578A JPS5585547A (en) 1978-12-25 1978-12-25 Preparation of substituted phenylacetic acid

Publications (2)

Publication Number Publication Date
JPS5585547A true JPS5585547A (en) 1980-06-27
JPS565730B2 JPS565730B2 (en) 1981-02-06

Family

ID=15748509

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16212578A Granted JPS5585547A (en) 1978-12-25 1978-12-25 Preparation of substituted phenylacetic acid

Country Status (1)

Country Link
JP (1) JPS5585547A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4421756A (en) * 1979-10-12 1983-12-20 Daito Koeki Kabushiki Kaisha Quinolinoneimine carboxylic acid anti-inflammatory and analgesic composition containing the compound

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4421756A (en) * 1979-10-12 1983-12-20 Daito Koeki Kabushiki Kaisha Quinolinoneimine carboxylic acid anti-inflammatory and analgesic composition containing the compound

Also Published As

Publication number Publication date
JPS565730B2 (en) 1981-02-06

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