JPS57149257A - 4-benzyloxyphenylacetamide - Google Patents

4-benzyloxyphenylacetamide

Info

Publication number
JPS57149257A
JPS57149257A JP3632681A JP3632681A JPS57149257A JP S57149257 A JPS57149257 A JP S57149257A JP 3632681 A JP3632681 A JP 3632681A JP 3632681 A JP3632681 A JP 3632681A JP S57149257 A JPS57149257 A JP S57149257A
Authority
JP
Japan
Prior art keywords
formulai
useful
benzyloxyphenylacetamide
benzyloxyphenylacetonitrile
hydroxyphenylacetamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP3632681A
Other languages
Japanese (ja)
Inventor
Motoo Mutsuto
Shin Yamada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nissan Chemical Corp
Original Assignee
Nissan Chemical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Corp filed Critical Nissan Chemical Corp
Priority to JP3632681A priority Critical patent/JPS57149257A/en
Publication of JPS57149257A publication Critical patent/JPS57149257A/en
Pending legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:4-Benzyloxyphenylacetamide expressed by formulaI.
USE: Useful as an intermediate for preparing 4-(2-hydroxy-3-isopropylaminopropoxy)phenylacetamide ("Atenolol ") useful as a β-sympathetic inhibitor, easily convertible into a 4-hydroxyphenylacetamide, and industrially, easily, economically and advantageously obtainable.
PROCESS: 4-Benzyloxyphenylacetonitrile of formula II is reacted with hydrogen peroxide in the absence or presence of a solvent, e.g. ethanol or tetrahydrofuran, in the presence of an acidic catalyst, e.g. hydrogen chloride or sulfuric acid, or in an aqueous solution of an alkali to give the aimed compound of formulaI.
COPYRIGHT: (C)1982,JPO&Japio
JP3632681A 1981-03-13 1981-03-13 4-benzyloxyphenylacetamide Pending JPS57149257A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP3632681A JPS57149257A (en) 1981-03-13 1981-03-13 4-benzyloxyphenylacetamide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3632681A JPS57149257A (en) 1981-03-13 1981-03-13 4-benzyloxyphenylacetamide

Publications (1)

Publication Number Publication Date
JPS57149257A true JPS57149257A (en) 1982-09-14

Family

ID=12466709

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3632681A Pending JPS57149257A (en) 1981-03-13 1981-03-13 4-benzyloxyphenylacetamide

Country Status (1)

Country Link
JP (1) JPS57149257A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008545807A (en) * 2006-07-26 2008-12-18 テバ ファーマシューティカル インダストリーズ リミティド Method for synthesizing O-desmethylvenlafaxine

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008545807A (en) * 2006-07-26 2008-12-18 テバ ファーマシューティカル インダストリーズ リミティド Method for synthesizing O-desmethylvenlafaxine
JP4763788B2 (en) * 2006-07-26 2011-08-31 テバ ファーマシューティカル インダストリーズ リミティド Method for synthesizing O-desmethylvenlafaxine

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