JPS57136553A - Aminocarboxylic acid derivative, its preparation and antiulcer agent containing the same as active constituent - Google Patents
Aminocarboxylic acid derivative, its preparation and antiulcer agent containing the same as active constituentInfo
- Publication number
- JPS57136553A JPS57136553A JP56020820A JP2082081A JPS57136553A JP S57136553 A JPS57136553 A JP S57136553A JP 56020820 A JP56020820 A JP 56020820A JP 2082081 A JP2082081 A JP 2082081A JP S57136553 A JPS57136553 A JP S57136553A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound expressed
- expressed
- compound
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003699 antiulcer agent Substances 0.000 title abstract 2
- KXDHJXZQYSOELW-UHFFFAOYSA-N Carbamic acid Chemical class NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 title 1
- 239000000470 constituent Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 6
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 230000002496 gastric effect Effects 0.000 abstract 2
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 abstract 2
- 102000035195 Peptidases Human genes 0.000 abstract 1
- 108091005804 Peptidases Proteins 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000000767 anti-ulcer Effects 0.000 abstract 1
- 230000017531 blood circulation Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000004400 mucous membrane Anatomy 0.000 abstract 1
- -1 p-(4-Aminomethylbenzoyl)-phenylpropionic acid Chemical compound 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 229940024999 proteolytic enzymes for treatment of wounds and ulcers Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229940076279 serotonin Drugs 0.000 abstract 1
- 231100000397 ulcer Toxicity 0.000 abstract 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56020820A JPS57136553A (en) | 1981-02-17 | 1981-02-17 | Aminocarboxylic acid derivative, its preparation and antiulcer agent containing the same as active constituent |
| US06/284,562 US4402975A (en) | 1980-07-21 | 1981-07-17 | Aminocarboxylic acids, amino alcohols, or the derivatives thereof, processes for production thereof, and pharmaceutical uses thereof |
| EP81105629A EP0044541B1 (en) | 1980-07-21 | 1981-07-17 | Aminocarboxylic acids, amino alcohols, or the derivatives thereof, processes for production thereof, and pharmaceutical composition, containing at least one of these compounds |
| DE8181105629T DE3160959D1 (en) | 1980-07-21 | 1981-07-17 | Aminocarboxylic acids, amino alcohols, or the derivatives thereof, processes for production thereof, and pharmaceutical composition, containing at least one of these compounds |
| CA000382012A CA1176267A (en) | 1980-07-21 | 1981-07-20 | Aminocarboxylic acids, amino alcohols, or the derivatives thereof, processes for production thereof, and pharmaceutical uses thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56020820A JPS57136553A (en) | 1981-02-17 | 1981-02-17 | Aminocarboxylic acid derivative, its preparation and antiulcer agent containing the same as active constituent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS57136553A true JPS57136553A (en) | 1982-08-23 |
| JPS644509B2 JPS644509B2 (enExample) | 1989-01-25 |
Family
ID=12037665
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP56020820A Granted JPS57136553A (en) | 1980-07-21 | 1981-02-17 | Aminocarboxylic acid derivative, its preparation and antiulcer agent containing the same as active constituent |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS57136553A (enExample) |
-
1981
- 1981-02-17 JP JP56020820A patent/JPS57136553A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS644509B2 (enExample) | 1989-01-25 |
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