JPS5793996A - Glucosamine derivative and its preparation - Google Patents
Glucosamine derivative and its preparationInfo
- Publication number
- JPS5793996A JPS5793996A JP16907380A JP16907380A JPS5793996A JP S5793996 A JPS5793996 A JP S5793996A JP 16907380 A JP16907380 A JP 16907380A JP 16907380 A JP16907380 A JP 16907380A JP S5793996 A JPS5793996 A JP S5793996A
- Authority
- JP
- Japan
- Prior art keywords
- aluminum
- glucosamine
- glutamylglucosamine
- formula
- reacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:L-γ-Glutamyl-D-glucosamine aluminum salt of formulaI.
USE: An antiulcer agent. It has excellent effect to the digestive tracts, esp. the stomach and the duodenum.
PROCESS: The compound of formulaIis prepared by reacting L-γ-glutamylglucosamine of formula II with an aluminum alkoxide (e.g. aluminum isopropoxide, aluminum butoxide, etc.) in water or an alcoholic solvent for 1W5hr. The L-γ- glutamylglucosamine of formula II can be prepared by reacting glucosamine with N-cabobenzoxyglutaminic acid α-benzyl ester in the presence of dicyclohexyl carbodimide, and hydrolyzing the reaction product in the presence of palladium, thereby eliminating the carbobenzoxy group and the benzyl group.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16907380A JPS5793996A (en) | 1980-12-02 | 1980-12-02 | Glucosamine derivative and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16907380A JPS5793996A (en) | 1980-12-02 | 1980-12-02 | Glucosamine derivative and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5793996A true JPS5793996A (en) | 1982-06-11 |
Family
ID=15879818
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP16907380A Pending JPS5793996A (en) | 1980-12-02 | 1980-12-02 | Glucosamine derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5793996A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008195705A (en) * | 2007-01-15 | 2008-08-28 | Daiichi Sankyo Healthcare Co Ltd | Loxoprofen-containing oral composition |
-
1980
- 1980-12-02 JP JP16907380A patent/JPS5793996A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008195705A (en) * | 2007-01-15 | 2008-08-28 | Daiichi Sankyo Healthcare Co Ltd | Loxoprofen-containing oral composition |
JP2013209427A (en) * | 2007-01-15 | 2013-10-10 | Daiichi Sankyo Healthcare Co Ltd | Loxoprofen-containing oral composition |
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