JPS5793996A - Glucosamine derivative and its preparation - Google Patents

Glucosamine derivative and its preparation

Info

Publication number
JPS5793996A
JPS5793996A JP16907380A JP16907380A JPS5793996A JP S5793996 A JPS5793996 A JP S5793996A JP 16907380 A JP16907380 A JP 16907380A JP 16907380 A JP16907380 A JP 16907380A JP S5793996 A JPS5793996 A JP S5793996A
Authority
JP
Japan
Prior art keywords
aluminum
glucosamine
glutamylglucosamine
formula
reacting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP16907380A
Other languages
Japanese (ja)
Inventor
Shiro Kudo
Hiromitsu Aonuma
Takami Sato
Akira Kawamoto
Yoshiyuki Kimizuka
Makoto Miwa
Kuniaki Taguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kawaken Fine Chemicals Co Ltd
Nippon Chemiphar Co Ltd
Original Assignee
Kawaken Fine Chemicals Co Ltd
Nippon Chemiphar Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kawaken Fine Chemicals Co Ltd, Nippon Chemiphar Co Ltd filed Critical Kawaken Fine Chemicals Co Ltd
Priority to JP16907380A priority Critical patent/JPS5793996A/en
Publication of JPS5793996A publication Critical patent/JPS5793996A/en
Pending legal-status Critical Current

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  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:L-γ-Glutamyl-D-glucosamine aluminum salt of formulaI.
USE: An antiulcer agent. It has excellent effect to the digestive tracts, esp. the stomach and the duodenum.
PROCESS: The compound of formulaIis prepared by reacting L-γ-glutamylglucosamine of formula II with an aluminum alkoxide (e.g. aluminum isopropoxide, aluminum butoxide, etc.) in water or an alcoholic solvent for 1W5hr. The L-γ- glutamylglucosamine of formula II can be prepared by reacting glucosamine with N-cabobenzoxyglutaminic acid α-benzyl ester in the presence of dicyclohexyl carbodimide, and hydrolyzing the reaction product in the presence of palladium, thereby eliminating the carbobenzoxy group and the benzyl group.
COPYRIGHT: (C)1982,JPO&Japio
JP16907380A 1980-12-02 1980-12-02 Glucosamine derivative and its preparation Pending JPS5793996A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16907380A JPS5793996A (en) 1980-12-02 1980-12-02 Glucosamine derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16907380A JPS5793996A (en) 1980-12-02 1980-12-02 Glucosamine derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS5793996A true JPS5793996A (en) 1982-06-11

Family

ID=15879818

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16907380A Pending JPS5793996A (en) 1980-12-02 1980-12-02 Glucosamine derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS5793996A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008195705A (en) * 2007-01-15 2008-08-28 Daiichi Sankyo Healthcare Co Ltd Loxoprofen-containing oral composition

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008195705A (en) * 2007-01-15 2008-08-28 Daiichi Sankyo Healthcare Co Ltd Loxoprofen-containing oral composition
JP2013209427A (en) * 2007-01-15 2013-10-10 Daiichi Sankyo Healthcare Co Ltd Loxoprofen-containing oral composition

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