JPS5677281A - Antibiotic heptelidic acid and its preparation - Google Patents

Antibiotic heptelidic acid and its preparation

Info

Publication number
JPS5677281A
JPS5677281A JP15467979A JP15467979A JPS5677281A JP S5677281 A JPS5677281 A JP S5677281A JP 15467979 A JP15467979 A JP 15467979A JP 15467979 A JP15467979 A JP 15467979A JP S5677281 A JPS5677281 A JP S5677281A
Authority
JP
Japan
Prior art keywords
antibiotic
strain
ferm
filtrate
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP15467979A
Other languages
Japanese (ja)
Inventor
Mamoru Arai
Tatsuo Haishi
Yasuhiro Ito
Hideji Takahashi
Kohei Furuya
Kentaro Kodama
Hiroshi Takiguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Priority to JP15467979A priority Critical patent/JPS5677281A/en
Publication of JPS5677281A publication Critical patent/JPS5677281A/en
Pending legal-status Critical Current

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Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:Heptelicid acid shown by the formula and its salt.
USE: An antibiotic. Effective against an obligate Gram-negative bacterium, especially against Bacteroides fragilis, having a strong antibacterial activity against a cliincally separated strain as well as a sensitive bacterium.
PROCESS: A strain SANK 12679(FERM-P 5284) of Gliocladium Virens, strain SANK 13379 (FERM-P 5284) of Cheatomim globosum, or strain SANK 13479 (FREM-P 5282) of Trichlderma viride is cultivated in a liquid medium at 20W 30°C to give a culture solution, which is filterted or centrifuged. Heptelidic acid shown by the formula is extracted or purified from the filtrate or the supernatant liquid. The extraction, example, is carried out by passing for the filtrate through a layer of active carbon, etc. so that impurities are adsorbed and removed.
COPYRIGHT: (C)1981,JPO&Japio
JP15467979A 1979-11-29 1979-11-29 Antibiotic heptelidic acid and its preparation Pending JPS5677281A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP15467979A JPS5677281A (en) 1979-11-29 1979-11-29 Antibiotic heptelidic acid and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15467979A JPS5677281A (en) 1979-11-29 1979-11-29 Antibiotic heptelidic acid and its preparation

Publications (1)

Publication Number Publication Date
JPS5677281A true JPS5677281A (en) 1981-06-25

Family

ID=15589536

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15467979A Pending JPS5677281A (en) 1979-11-29 1979-11-29 Antibiotic heptelidic acid and its preparation

Country Status (1)

Country Link
JP (1) JPS5677281A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4500951B1 (en) * 2009-08-07 2010-07-14 学校法人神戸学院 DNA synthase inhibitors
JP2016140291A (en) * 2015-01-30 2016-08-08 公益財団法人野田産業科学研究所 Antibacterial substance

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4500951B1 (en) * 2009-08-07 2010-07-14 学校法人神戸学院 DNA synthase inhibitors
WO2011016351A1 (en) * 2009-08-07 2011-02-10 学校法人神戸学院 Dna synthase inhibitors
JP2011037730A (en) * 2009-08-07 2011-02-24 Kobe Gakuin Dna synthase inhibitor
JP2016140291A (en) * 2015-01-30 2016-08-08 公益財団法人野田産業科学研究所 Antibacterial substance

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