JPS5677281A - Antibiotic heptelidic acid and its preparation - Google Patents
Antibiotic heptelidic acid and its preparationInfo
- Publication number
- JPS5677281A JPS5677281A JP15467979A JP15467979A JPS5677281A JP S5677281 A JPS5677281 A JP S5677281A JP 15467979 A JP15467979 A JP 15467979A JP 15467979 A JP15467979 A JP 15467979A JP S5677281 A JPS5677281 A JP S5677281A
- Authority
- JP
- Japan
- Prior art keywords
- antibiotic
- strain
- ferm
- filtrate
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:Heptelicid acid shown by the formula and its salt.
USE: An antibiotic. Effective against an obligate Gram-negative bacterium, especially against Bacteroides fragilis, having a strong antibacterial activity against a cliincally separated strain as well as a sensitive bacterium.
PROCESS: A strain SANK 12679(FERM-P 5284) of Gliocladium Virens, strain SANK 13379 (FERM-P 5284) of Cheatomim globosum, or strain SANK 13479 (FREM-P 5282) of Trichlderma viride is cultivated in a liquid medium at 20W 30°C to give a culture solution, which is filterted or centrifuged. Heptelidic acid shown by the formula is extracted or purified from the filtrate or the supernatant liquid. The extraction, example, is carried out by passing for the filtrate through a layer of active carbon, etc. so that impurities are adsorbed and removed.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15467979A JPS5677281A (en) | 1979-11-29 | 1979-11-29 | Antibiotic heptelidic acid and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15467979A JPS5677281A (en) | 1979-11-29 | 1979-11-29 | Antibiotic heptelidic acid and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5677281A true JPS5677281A (en) | 1981-06-25 |
Family
ID=15589536
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP15467979A Pending JPS5677281A (en) | 1979-11-29 | 1979-11-29 | Antibiotic heptelidic acid and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5677281A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4500951B1 (en) * | 2009-08-07 | 2010-07-14 | 学校法人神戸学院 | DNA synthase inhibitors |
JP2016140291A (en) * | 2015-01-30 | 2016-08-08 | 公益財団法人野田産業科学研究所 | Antibacterial substance |
-
1979
- 1979-11-29 JP JP15467979A patent/JPS5677281A/en active Pending
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4500951B1 (en) * | 2009-08-07 | 2010-07-14 | 学校法人神戸学院 | DNA synthase inhibitors |
WO2011016351A1 (en) * | 2009-08-07 | 2011-02-10 | 学校法人神戸学院 | Dna synthase inhibitors |
JP2011037730A (en) * | 2009-08-07 | 2011-02-24 | Kobe Gakuin | Dna synthase inhibitor |
JP2016140291A (en) * | 2015-01-30 | 2016-08-08 | 公益財団法人野田産業科学研究所 | Antibacterial substance |
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