JPS5711977A - Purifying method of 5-acetamido-1,2,3-thiadiazole - Google Patents
Purifying method of 5-acetamido-1,2,3-thiadiazoleInfo
- Publication number
- JPS5711977A JPS5711977A JP8658780A JP8658780A JPS5711977A JP S5711977 A JPS5711977 A JP S5711977A JP 8658780 A JP8658780 A JP 8658780A JP 8658780 A JP8658780 A JP 8658780A JP S5711977 A JPS5711977 A JP S5711977A
- Authority
- JP
- Japan
- Prior art keywords
- thiadiazole
- acetamido
- water
- crude
- alkali
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Abstract
PURPOSE: To purify crude 5-acetamido-1,2,3-thiadiazole useful as a synthetic raw material for a cephalosporin antibiotic cephatridine, etc. in high yield, by dissolving the crude substance in water in the presence of an alkali to remove impurities.
CONSTITUTION: 5-Chlro-1,2,3-thiadiazole is reacted with ammonia, and the reaction product is then acetylated to give crude 5-acetamido-1,2,3-thiadiazole, which is dissolved in water in the presence of one equivalent amount or more alkali, e.g. NaOH or KOH. By-products insoluble in water are then filtered off to afford the aimed purified compound.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8658780A JPS5711977A (en) | 1980-06-27 | 1980-06-27 | Purifying method of 5-acetamido-1,2,3-thiadiazole |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8658780A JPS5711977A (en) | 1980-06-27 | 1980-06-27 | Purifying method of 5-acetamido-1,2,3-thiadiazole |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5711977A true JPS5711977A (en) | 1982-01-21 |
Family
ID=13891135
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP8658780A Pending JPS5711977A (en) | 1980-06-27 | 1980-06-27 | Purifying method of 5-acetamido-1,2,3-thiadiazole |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5711977A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4594424A (en) * | 1983-07-12 | 1986-06-10 | Ube Industries, Ltd. | 5-mercapto-1,2,3-thiadiazoles composition and process for preparing the same |
JPH0495931U (en) * | 1991-01-11 | 1992-08-19 | ||
US8178141B2 (en) | 2005-01-27 | 2012-05-15 | The Folger Coffee Company | Articles of manufacture and methods for absorbing gasses released by roasted coffee packed in hermetically sealed containers |
-
1980
- 1980-06-27 JP JP8658780A patent/JPS5711977A/en active Pending
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4594424A (en) * | 1983-07-12 | 1986-06-10 | Ube Industries, Ltd. | 5-mercapto-1,2,3-thiadiazoles composition and process for preparing the same |
JPH0495931U (en) * | 1991-01-11 | 1992-08-19 | ||
US8178141B2 (en) | 2005-01-27 | 2012-05-15 | The Folger Coffee Company | Articles of manufacture and methods for absorbing gasses released by roasted coffee packed in hermetically sealed containers |
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