JPS5711977A - Purifying method of 5-acetamido-1,2,3-thiadiazole - Google Patents

Purifying method of 5-acetamido-1,2,3-thiadiazole

Info

Publication number
JPS5711977A
JPS5711977A JP8658780A JP8658780A JPS5711977A JP S5711977 A JPS5711977 A JP S5711977A JP 8658780 A JP8658780 A JP 8658780A JP 8658780 A JP8658780 A JP 8658780A JP S5711977 A JPS5711977 A JP S5711977A
Authority
JP
Japan
Prior art keywords
thiadiazole
acetamido
water
crude
alkali
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8658780A
Other languages
Japanese (ja)
Inventor
Ikuo Matsumoto
Kusuo Osumi
Junji Yoshizawa
Toshihisa Ichida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MSD KK
Original Assignee
Banyu Phamaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Banyu Phamaceutical Co Ltd filed Critical Banyu Phamaceutical Co Ltd
Priority to JP8658780A priority Critical patent/JPS5711977A/en
Publication of JPS5711977A publication Critical patent/JPS5711977A/en
Pending legal-status Critical Current

Links

Landscapes

  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

PURPOSE: To purify crude 5-acetamido-1,2,3-thiadiazole useful as a synthetic raw material for a cephalosporin antibiotic cephatridine, etc. in high yield, by dissolving the crude substance in water in the presence of an alkali to remove impurities.
CONSTITUTION: 5-Chlro-1,2,3-thiadiazole is reacted with ammonia, and the reaction product is then acetylated to give crude 5-acetamido-1,2,3-thiadiazole, which is dissolved in water in the presence of one equivalent amount or more alkali, e.g. NaOH or KOH. By-products insoluble in water are then filtered off to afford the aimed purified compound.
COPYRIGHT: (C)1982,JPO&Japio
JP8658780A 1980-06-27 1980-06-27 Purifying method of 5-acetamido-1,2,3-thiadiazole Pending JPS5711977A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8658780A JPS5711977A (en) 1980-06-27 1980-06-27 Purifying method of 5-acetamido-1,2,3-thiadiazole

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8658780A JPS5711977A (en) 1980-06-27 1980-06-27 Purifying method of 5-acetamido-1,2,3-thiadiazole

Publications (1)

Publication Number Publication Date
JPS5711977A true JPS5711977A (en) 1982-01-21

Family

ID=13891135

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8658780A Pending JPS5711977A (en) 1980-06-27 1980-06-27 Purifying method of 5-acetamido-1,2,3-thiadiazole

Country Status (1)

Country Link
JP (1) JPS5711977A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4594424A (en) * 1983-07-12 1986-06-10 Ube Industries, Ltd. 5-mercapto-1,2,3-thiadiazoles composition and process for preparing the same
JPH0495931U (en) * 1991-01-11 1992-08-19
US8178141B2 (en) 2005-01-27 2012-05-15 The Folger Coffee Company Articles of manufacture and methods for absorbing gasses released by roasted coffee packed in hermetically sealed containers

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4594424A (en) * 1983-07-12 1986-06-10 Ube Industries, Ltd. 5-mercapto-1,2,3-thiadiazoles composition and process for preparing the same
JPH0495931U (en) * 1991-01-11 1992-08-19
US8178141B2 (en) 2005-01-27 2012-05-15 The Folger Coffee Company Articles of manufacture and methods for absorbing gasses released by roasted coffee packed in hermetically sealed containers

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