JPS565483A - Purification of cephalosporin compound - Google Patents

Purification of cephalosporin compound

Info

Publication number
JPS565483A
JPS565483A JP8046779A JP8046779A JPS565483A JP S565483 A JPS565483 A JP S565483A JP 8046779 A JP8046779 A JP 8046779A JP 8046779 A JP8046779 A JP 8046779A JP S565483 A JPS565483 A JP S565483A
Authority
JP
Japan
Prior art keywords
compound
cephalosporin compound
solvent
high yield
alcohol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8046779A
Other languages
Japanese (ja)
Inventor
Hirotada Yamada
Hiroyuki Suzuki
Seiichi Jinbo
Hisao Tohiki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Priority to JP8046779A priority Critical patent/JPS565483A/en
Publication of JPS565483A publication Critical patent/JPS565483A/en
Pending legal-status Critical Current

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  • Cephalosporin Compounds (AREA)

Abstract

PURPOSE: To obtain a purified cephalosporin compound useful as an antimicrobial or feed additive in a continuous process in high yield, by decomposing a crude cephalosporin compound with a salt in the presence of a specific organic solvent, and by oxidizing the freed compound.
CONSTITUTION: A crude cephalosporin compound of the formula (A is pyridyl ring; R is hydroxyl-substituted phenyl group; Het is 1W4C lower alkyl-substituted tetrazole; M is alkali metal, alkaline earth metal or organic amine salt) is decomposed with a slat in an amide solvent to give a crystalline free acid solvate compound. In this reaction, an organic alcohol or/and keton solvent is present in any stage. Methanol may be cited as the alcohol; acetone, as the ketone.
EFFECT: High purity enough to be administrable to a man or animal, and high yield.
COPYRIGHT: (C)1981,JPO&Japio
JP8046779A 1979-06-25 1979-06-25 Purification of cephalosporin compound Pending JPS565483A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8046779A JPS565483A (en) 1979-06-25 1979-06-25 Purification of cephalosporin compound

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8046779A JPS565483A (en) 1979-06-25 1979-06-25 Purification of cephalosporin compound

Publications (1)

Publication Number Publication Date
JPS565483A true JPS565483A (en) 1981-01-20

Family

ID=13719056

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8046779A Pending JPS565483A (en) 1979-06-25 1979-06-25 Purification of cephalosporin compound

Country Status (1)

Country Link
JP (1) JPS565483A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6329372B1 (en) * 1998-01-27 2001-12-11 Celltech Therapeutics Limited Phenylalanine derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6329372B1 (en) * 1998-01-27 2001-12-11 Celltech Therapeutics Limited Phenylalanine derivatives

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