JPS57134489A - Novel cephalosporins and their preparations - Google Patents

Novel cephalosporins and their preparations

Info

Publication number
JPS57134489A
JPS57134489A JP2034881A JP2034881A JPS57134489A JP S57134489 A JPS57134489 A JP S57134489A JP 2034881 A JP2034881 A JP 2034881A JP 2034881 A JP2034881 A JP 2034881A JP S57134489 A JPS57134489 A JP S57134489A
Authority
JP
Japan
Prior art keywords
compound shown
formulai
gram
alkyl
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2034881A
Other languages
Japanese (ja)
Other versions
JPS6043075B2 (en
Inventor
Shigeo Shimizu
Hiroyuki Takano
Shoji Yoshimura
Kinji Takada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NIHON IYAKUHIN KAIHATSU KENKYU
NIHON IYAKUHIN KAIHATSU KENKYUSHO KK
NIPPON IYAKUHIN KAIHATSU KENKYUSHO KK
SANKEI YAKUHIN KK
Original Assignee
NIHON IYAKUHIN KAIHATSU KENKYU
NIHON IYAKUHIN KAIHATSU KENKYUSHO KK
NIPPON IYAKUHIN KAIHATSU KENKYUSHO KK
SANKEI YAKUHIN KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NIHON IYAKUHIN KAIHATSU KENKYU, NIHON IYAKUHIN KAIHATSU KENKYUSHO KK, NIPPON IYAKUHIN KAIHATSU KENKYUSHO KK, SANKEI YAKUHIN KK filed Critical NIHON IYAKUHIN KAIHATSU KENKYU
Priority to JP2034881A priority Critical patent/JPS6043075B2/en
Priority to US06/337,380 priority patent/US4436904A/en
Priority to DE19823200400 priority patent/DE3200400A1/en
Priority to GB08410874A priority patent/GB2136810B/en
Priority to GB08410873A priority patent/GB2137623B/en
Priority to GB08410875A priority patent/GB2137624B/en
Priority to GB8200687A priority patent/GB2093447B/en
Priority to FR8202341A priority patent/FR2499994B1/en
Priority to IT19626/82A priority patent/IT1157264B/en
Priority to CH895/82A priority patent/CH651573A5/en
Publication of JPS57134489A publication Critical patent/JPS57134489A/en
Priority to FR8215458A priority patent/FR2513253B1/en
Publication of JPS6043075B2 publication Critical patent/JPS6043075B2/en
Expired legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

NEW MATERIAL:A compound shown by the formulaI[R is H, alkyl; R' is H, alkali metal, organic amine, ester moiety; R1 and R2 are R; Y is H, OH, OC(O) R5(R5 is alkyl, aryl, alkoxy); Z is H, halogen; P is 1 or 2].
EXAMPLE: Sodium 7{D-(-)-α-[( 2-oxo-3-( 1, 3-dithiolan-2-imino )-imidazolidine-1- yl )-carboxamide]-phenylacetamide}-3-[( 1,3,4-thiadiazole-2-yl )-thiomethyl]-3- cephem-4-carboxylate.
USE: An antibacterial agent. Exhibiting an improved antibacterial action on a wide range of pathogenic bacteria of Gram-positive and Gram-negative bacteria including Pseudomonas aeruginosa.
PROCESS: A compound shown by the formula II is reacted with a compound shown by the formula III or its reactive derivative, and, if necessary, the resulted compound is acylated or esterified, to geve a compound shown by the formulaI.
COPYRIGHT: (C)1982,JPO&Japio
JP2034881A 1981-02-14 1981-02-14 Novel cephalosporins and their production method Expired JPS6043075B2 (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
JP2034881A JPS6043075B2 (en) 1981-02-14 1981-02-14 Novel cephalosporins and their production method
US06/337,380 US4436904A (en) 1981-02-14 1982-01-06 Cephalosporins
DE19823200400 DE3200400A1 (en) 1981-02-14 1982-01-08 CEPHALOSPORINE DERIVATIVES
GB08410875A GB2137624B (en) 1981-02-14 1982-01-11 Novel dithiolaniminoxoimidazolidines
GB08410873A GB2137623B (en) 1981-02-14 1982-01-11 Novel dithiolaniminoimidazolidine carboxylic acids
GB08410874A GB2136810B (en) 1981-02-14 1982-01-11 Novel dithiolaniminoimidazolidine carboxyamido carboxlyic acids
GB8200687A GB2093447B (en) 1981-02-14 1982-01-11 Novel cephalosporins and processes for preparation thereof
FR8202341A FR2499994B1 (en) 1981-02-14 1982-02-12 NEW CEPHALOSPORINS, THEIR PREPARATION AND INTERMEDIATE PRODUCTS OBTAINED
IT19626/82A IT1157264B (en) 1981-02-14 1982-02-12 CEPHALOSPORINE AND PROCEDURES FOR THEIR PREPARATION
CH895/82A CH651573A5 (en) 1981-02-14 1982-02-12 CEPHALOSPORIN DERIVATIVES.
FR8215458A FR2513253B1 (en) 1981-02-14 1982-09-13 NOVEL 2-OXO-3- (1,3-DITHIOLAN-2-IMINO) -IMIDAZOLIDINE DERIVATIVES AND THEIR PREPARATION PROCESS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2034881A JPS6043075B2 (en) 1981-02-14 1981-02-14 Novel cephalosporins and their production method

Publications (2)

Publication Number Publication Date
JPS57134489A true JPS57134489A (en) 1982-08-19
JPS6043075B2 JPS6043075B2 (en) 1985-09-26

Family

ID=12024614

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2034881A Expired JPS6043075B2 (en) 1981-02-14 1981-02-14 Novel cephalosporins and their production method

Country Status (1)

Country Link
JP (1) JPS6043075B2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6282712U (en) * 1985-11-12 1987-05-27

Also Published As

Publication number Publication date
JPS6043075B2 (en) 1985-09-26

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