JPS57106663A - 1,4-disubstituted piperazine derivative and its preparation - Google Patents

1,4-disubstituted piperazine derivative and its preparation

Info

Publication number
JPS57106663A
JPS57106663A JP55182632A JP18263280A JPS57106663A JP S57106663 A JPS57106663 A JP S57106663A JP 55182632 A JP55182632 A JP 55182632A JP 18263280 A JP18263280 A JP 18263280A JP S57106663 A JPS57106663 A JP S57106663A
Authority
JP
Japan
Prior art keywords
formula
disubstituted piperazine
preparation
compound shown
piperazine derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP55182632A
Other languages
English (en)
Japanese (ja)
Inventor
Tsutomu Irikura
Keigo Nishino
Hisaya Okamura
Fukutaro Taga
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyorin Pharmaceutical Co Ltd
Original Assignee
Kyorin Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Pharmaceutical Co Ltd filed Critical Kyorin Pharmaceutical Co Ltd
Priority to JP55182632A priority Critical patent/JPS57106663A/ja
Priority to SE8107680A priority patent/SE8107680L/xx
Priority to IT25742/81A priority patent/IT1142620B/it
Priority to AU78774/81A priority patent/AU7877481A/en
Priority to BE0/206904A priority patent/BE891580A/fr
Priority to FR8124075A priority patent/FR2496661A1/fr
Priority to KR1019810005097A priority patent/KR830007608A/ko
Priority to GB8138720A priority patent/GB2091255A/en
Priority to ZA818900A priority patent/ZA818900B/xx
Priority to DE19813151123 priority patent/DE3151123A1/de
Publication of JPS57106663A publication Critical patent/JPS57106663A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/14—Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP55182632A 1980-12-23 1980-12-23 1,4-disubstituted piperazine derivative and its preparation Pending JPS57106663A (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
JP55182632A JPS57106663A (en) 1980-12-23 1980-12-23 1,4-disubstituted piperazine derivative and its preparation
SE8107680A SE8107680L (sv) 1980-12-23 1981-12-21 Piperazinderivat och forfarande for framstellning derav
IT25742/81A IT1142620B (it) 1980-12-23 1981-12-21 Derivati piperazinici 1,4-bisostituiti e processo per la loro preparazione
AU78774/81A AU7877481A (en) 1980-12-23 1981-12-22 1-heteroalkyl,4-benzoyl substituted piperazines
BE0/206904A BE891580A (fr) 1980-12-23 1981-12-22 Derives de piperazine 1,4-disubstitues et leur procede de preparation
FR8124075A FR2496661A1 (fr) 1980-12-23 1981-12-23 Derives de substitution en 1,4 de la piperazine, leur preparation et medicament contenant ces substances
KR1019810005097A KR830007608A (ko) 1980-12-23 1981-12-23 1,4-2치환 피페라진 유도체의 제조방법
GB8138720A GB2091255A (en) 1980-12-23 1981-12-23 1,4-Disubstituted piperazine derivatives and process for the preparation thereof
ZA818900A ZA818900B (en) 1980-12-23 1981-12-23 1,4-disubstituted piperazine derivatives and process for the preparation thereof
DE19813151123 DE3151123A1 (de) 1980-12-23 1981-12-23 1,4-disubstituierte piperazinderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zubereitungen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55182632A JPS57106663A (en) 1980-12-23 1980-12-23 1,4-disubstituted piperazine derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS57106663A true JPS57106663A (en) 1982-07-02

Family

ID=16121678

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55182632A Pending JPS57106663A (en) 1980-12-23 1980-12-23 1,4-disubstituted piperazine derivative and its preparation

Country Status (10)

Country Link
JP (1) JPS57106663A (xx)
KR (1) KR830007608A (xx)
AU (1) AU7877481A (xx)
BE (1) BE891580A (xx)
DE (1) DE3151123A1 (xx)
FR (1) FR2496661A1 (xx)
GB (1) GB2091255A (xx)
IT (1) IT1142620B (xx)
SE (1) SE8107680L (xx)
ZA (1) ZA818900B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4835154A (en) * 1987-06-01 1989-05-30 Smithkline Beckman Corporation 1-aralykyl-5-piperazinylmethyl-2-mercaptoimidazoles and 2-alkylthioimidazoles and their use as dopamine-βhydroxylase inhibitors
US5149700A (en) * 1990-05-30 1992-09-22 American Home Products Corporation Substituted arylsulfonamides and benzamides
AU3248600A (en) * 1999-03-03 2000-09-21 Merck & Co., Inc. Inhibitors of prenyl-protein transferases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2297045A1 (fr) * 1975-01-10 1976-08-06 Delalande Sa Nouveaux (aroyl-2' eth-1' yl)-1 (acetamido-4'' piperazin-1'' yl methyl)-2 benzimidazoles a proprietes antisecretoire gastrique et antiulcereuse
YU39992B (en) * 1976-04-02 1985-06-30 Janssen Pharmaceutica Nv Process for obtaining new piperazine and piperidine derivatives

Also Published As

Publication number Publication date
BE891580A (fr) 1982-04-16
ZA818900B (en) 1982-12-29
DE3151123A1 (de) 1982-08-12
FR2496661A1 (fr) 1982-06-25
SE8107680L (sv) 1982-06-24
AU7877481A (en) 1982-07-01
GB2091255A (en) 1982-07-28
IT1142620B (it) 1986-10-08
IT8125742A0 (it) 1981-12-21
KR830007608A (ko) 1983-11-04

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