JPS5661395A - Piperazinylalkylphosphonic acid derivative - Google Patents

Piperazinylalkylphosphonic acid derivative

Info

Publication number
JPS5661395A
JPS5661395A JP13707079A JP13707079A JPS5661395A JP S5661395 A JPS5661395 A JP S5661395A JP 13707079 A JP13707079 A JP 13707079A JP 13707079 A JP13707079 A JP 13707079A JP S5661395 A JPS5661395 A JP S5661395A
Authority
JP
Japan
Prior art keywords
formula
expressed
solvent
piperazinylalkylphosphonic
acid derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP13707079A
Other languages
Japanese (ja)
Inventor
Kazuo Kikazawa
Mineji Hiiragi
Kikuo Wakizaka
Hideo Sugi
Shigeru Yamabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aska Pharmaceutical Co Ltd
Original Assignee
Grelan Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grelan Pharmaceutical Co Ltd filed Critical Grelan Pharmaceutical Co Ltd
Priority to JP13707079A priority Critical patent/JPS5661395A/en
Publication of JPS5661395A publication Critical patent/JPS5661395A/en
Pending legal-status Critical Current

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Abstract

NEW MATERIAL:The titled derivative expressed by formula I [B is 1W4C lower alkylene when A is alanyl group expressed by formula II, and B is lower α-propionylaminoalkylene expressed by formula III (Y is 1W4C lower alkylene) when A is H or lower alkyl].
EXAMPLE: 4-Alanylpiperazinylmethylphosphonic acid.
USE: A raw material for a medicine having an antimicrobial action.
PROCESS: A piperazine derivative, e.g. alanylpiperazine, is reacted with a phosphonic ester, e.g. dibenzyl phosphite, and an aldehyde or ketone, e.g. formalin, under heating in a solvent, e.g. benzene. After the reaction, the solvent is distilled off, and the residue is purified by gel column chromatography to give the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
JP13707079A 1979-10-25 1979-10-25 Piperazinylalkylphosphonic acid derivative Pending JPS5661395A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP13707079A JPS5661395A (en) 1979-10-25 1979-10-25 Piperazinylalkylphosphonic acid derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13707079A JPS5661395A (en) 1979-10-25 1979-10-25 Piperazinylalkylphosphonic acid derivative

Publications (1)

Publication Number Publication Date
JPS5661395A true JPS5661395A (en) 1981-05-26

Family

ID=15190190

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13707079A Pending JPS5661395A (en) 1979-10-25 1979-10-25 Piperazinylalkylphosphonic acid derivative

Country Status (1)

Country Link
JP (1) JPS5661395A (en)

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