JPS5659708A - Dividable medicine controlling and delaying active substance release - Google Patents

Dividable medicine controlling and delaying active substance release

Info

Publication number
JPS5659708A
JPS5659708A JP11186280A JP11186280A JPS5659708A JP S5659708 A JPS5659708 A JP S5659708A JP 11186280 A JP11186280 A JP 11186280A JP 11186280 A JP11186280 A JP 11186280A JP S5659708 A JPS5659708 A JP S5659708A
Authority
JP
Japan
Prior art keywords
dividable
active substance
substance release
medicine controlling
delaying
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP11186280A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6361928B2 (Direct
Inventor
Hesu Hansu
Fuerumi Karuro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of JPS5659708A publication Critical patent/JPS5659708A/ja
Publication of JPS6361928B2 publication Critical patent/JPS6361928B2/ja
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/10Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
JP11186280A 1979-08-16 1980-08-15 Dividable medicine controlling and delaying active substance release Granted JPS5659708A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH7514/79A CH648754A5 (en) 1979-08-16 1979-08-16 Pharmaceutical slow release tablet

Publications (2)

Publication Number Publication Date
JPS5659708A true JPS5659708A (en) 1981-05-23
JPS6361928B2 JPS6361928B2 (Direct) 1988-11-30

Family

ID=4326338

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11186280A Granted JPS5659708A (en) 1979-08-16 1980-08-15 Dividable medicine controlling and delaying active substance release

Country Status (4)

Country Link
JP (1) JPS5659708A (Direct)
BE (1) BE884760A (Direct)
CH (1) CH648754A5 (Direct)
ZA (1) ZA805015B (Direct)

Cited By (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62141027U (Direct) * 1986-02-24 1987-09-05
JPH0537924U (ja) * 1991-09-10 1993-05-21 武田薬品工業株式会社 分割自在固形体
JP2002528408A (ja) * 1998-10-23 2002-09-03 ファイザー・インク cGMPPDE−5阻害剤を含有する制御放出性医薬製剤
JP2004525089A (ja) * 2000-12-13 2004-08-19 ソレックス リミテッド ブリケット
JP2008500401A (ja) * 2004-05-21 2008-01-10 アキュ−ブレイク テクノロジーズ インコーポレーテッド 複数のセグメントを含む、刻み目のある医薬錠剤
JP2009541341A (ja) * 2006-06-19 2009-11-26 エーシーシーユー−ブレイク テクノロジーズ,インク. セグメント状の薬剤の剤形
JP2010209103A (ja) * 2008-03-21 2010-09-24 Lab Servier 活性成分の調整放出が可能な分割可能なガレヌス形態
JP2011510034A (ja) * 2008-01-25 2011-03-31 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 医薬投薬形
WO2013187395A1 (ja) * 2012-06-12 2013-12-19 第一三共株式会社 容易な服用性と分割性を有する錠剤
JP5719479B1 (ja) * 2013-12-09 2015-05-20 第一三共株式会社 容易な分割性を有する錠剤
WO2015087561A1 (ja) * 2013-12-09 2015-06-18 第一三共株式会社 容易な分割性を有する錠剤
US9161917B2 (en) 2008-05-09 2015-10-20 Grünenthal GmbH Process for the preparation of a solid dosage form, in particular a tablet, for pharmaceutical use and process for the preparation of a precursor for a solid dosage form, in particular a tablet
US9629807B2 (en) 2003-08-06 2017-04-25 Grünenthal GmbH Abuse-proofed dosage form
US9636303B2 (en) 2010-09-02 2017-05-02 Gruenenthal Gmbh Tamper resistant dosage form comprising an anionic polymer
US9655853B2 (en) 2012-02-28 2017-05-23 Grünenthal GmbH Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer
US9675610B2 (en) 2002-06-17 2017-06-13 Grünenthal GmbH Abuse-proofed dosage form
US9737490B2 (en) 2013-05-29 2017-08-22 Grünenthal GmbH Tamper resistant dosage form with bimodal release profile
US9855263B2 (en) 2015-04-24 2018-01-02 Grünenthal GmbH Tamper-resistant dosage form with immediate release and resistance against solvent extraction
US9872835B2 (en) 2014-05-26 2018-01-23 Grünenthal GmbH Multiparticles safeguarded against ethanolic dose-dumping
US9913814B2 (en) 2014-05-12 2018-03-13 Grünenthal GmbH Tamper resistant immediate release capsule formulation comprising tapentadol
US9925146B2 (en) 2009-07-22 2018-03-27 Grünenthal GmbH Oxidation-stabilized tamper-resistant dosage form
US10058548B2 (en) 2003-08-06 2018-08-28 Grünenthal GmbH Abuse-proofed dosage form
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
US10080721B2 (en) 2009-07-22 2018-09-25 Gruenenthal Gmbh Hot-melt extruded pharmaceutical dosage form
US10130591B2 (en) 2003-08-06 2018-11-20 Grünenthal GmbH Abuse-proofed dosage form
US10154966B2 (en) 2013-05-29 2018-12-18 Grünenthal GmbH Tamper-resistant dosage form containing one or more particles
US10201502B2 (en) 2011-07-29 2019-02-12 Gruenenthal Gmbh Tamper-resistant tablet providing immediate drug release
US10300141B2 (en) 2010-09-02 2019-05-28 Grünenthal GmbH Tamper resistant dosage form comprising inorganic salt
US10335373B2 (en) 2012-04-18 2019-07-02 Grunenthal Gmbh Tamper resistant and dose-dumping resistant pharmaceutical dosage form
US10449547B2 (en) 2013-11-26 2019-10-22 Grünenthal GmbH Preparation of a powdery pharmaceutical composition by means of cryo-milling
US10624862B2 (en) 2013-07-12 2020-04-21 Grünenthal GmbH Tamper-resistant dosage form containing ethylene-vinyl acetate polymer
US10695297B2 (en) 2011-07-29 2020-06-30 Grünenthal GmbH Tamper-resistant tablet providing immediate drug release
US10729658B2 (en) 2005-02-04 2020-08-04 Grünenthal GmbH Process for the production of an abuse-proofed dosage form
US10842750B2 (en) 2015-09-10 2020-11-24 Grünenthal GmbH Protecting oral overdose with abuse deterrent immediate release formulations
US11224576B2 (en) 2003-12-24 2022-01-18 Grünenthal GmbH Process for the production of an abuse-proofed dosage form
US11844865B2 (en) 2004-07-01 2023-12-19 Grünenthal GmbH Abuse-proofed oral dosage form

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5259413B2 (ja) * 2005-11-18 2013-08-07 エーシーシーユー−ブレイク テクノロジーズ,インク. セグメント化した薬の剤形

Cited By (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62141027U (Direct) * 1986-02-24 1987-09-05
JPH0537924U (ja) * 1991-09-10 1993-05-21 武田薬品工業株式会社 分割自在固形体
JP2002528408A (ja) * 1998-10-23 2002-09-03 ファイザー・インク cGMPPDE−5阻害剤を含有する制御放出性医薬製剤
JP2004525089A (ja) * 2000-12-13 2004-08-19 ソレックス リミテッド ブリケット
US9675610B2 (en) 2002-06-17 2017-06-13 Grünenthal GmbH Abuse-proofed dosage form
US10369109B2 (en) 2002-06-17 2019-08-06 Grünenthal GmbH Abuse-proofed dosage form
US10058548B2 (en) 2003-08-06 2018-08-28 Grünenthal GmbH Abuse-proofed dosage form
US9629807B2 (en) 2003-08-06 2017-04-25 Grünenthal GmbH Abuse-proofed dosage form
US10130591B2 (en) 2003-08-06 2018-11-20 Grünenthal GmbH Abuse-proofed dosage form
US11224576B2 (en) 2003-12-24 2022-01-18 Grünenthal GmbH Process for the production of an abuse-proofed dosage form
JP2008500401A (ja) * 2004-05-21 2008-01-10 アキュ−ブレイク テクノロジーズ インコーポレーテッド 複数のセグメントを含む、刻み目のある医薬錠剤
JP2008500400A (ja) * 2004-05-21 2008-01-10 アキュ−ブレイク テクノロジーズ インコーポレーテッド 2個またはそれ以上の単位セグメントを含む医薬錠剤
US11844865B2 (en) 2004-07-01 2023-12-19 Grünenthal GmbH Abuse-proofed oral dosage form
US10675278B2 (en) 2005-02-04 2020-06-09 Grünenthal GmbH Crush resistant delayed-release dosage forms
US10729658B2 (en) 2005-02-04 2020-08-04 Grünenthal GmbH Process for the production of an abuse-proofed dosage form
JP2009541341A (ja) * 2006-06-19 2009-11-26 エーシーシーユー−ブレイク テクノロジーズ,インク. セグメント状の薬剤の剤形
JP2011510034A (ja) * 2008-01-25 2011-03-31 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 医薬投薬形
US9750701B2 (en) 2008-01-25 2017-09-05 Grünenthal GmbH Pharmaceutical dosage form
JP2010209103A (ja) * 2008-03-21 2010-09-24 Lab Servier 活性成分の調整放出が可能な分割可能なガレヌス形態
US9161917B2 (en) 2008-05-09 2015-10-20 Grünenthal GmbH Process for the preparation of a solid dosage form, in particular a tablet, for pharmaceutical use and process for the preparation of a precursor for a solid dosage form, in particular a tablet
US9925146B2 (en) 2009-07-22 2018-03-27 Grünenthal GmbH Oxidation-stabilized tamper-resistant dosage form
US10493033B2 (en) 2009-07-22 2019-12-03 Grünenthal GmbH Oxidation-stabilized tamper-resistant dosage form
US10080721B2 (en) 2009-07-22 2018-09-25 Gruenenthal Gmbh Hot-melt extruded pharmaceutical dosage form
US10300141B2 (en) 2010-09-02 2019-05-28 Grünenthal GmbH Tamper resistant dosage form comprising inorganic salt
US9636303B2 (en) 2010-09-02 2017-05-02 Gruenenthal Gmbh Tamper resistant dosage form comprising an anionic polymer
US10864164B2 (en) 2011-07-29 2020-12-15 Grünenthal GmbH Tamper-resistant tablet providing immediate drug release
US10695297B2 (en) 2011-07-29 2020-06-30 Grünenthal GmbH Tamper-resistant tablet providing immediate drug release
US10201502B2 (en) 2011-07-29 2019-02-12 Gruenenthal Gmbh Tamper-resistant tablet providing immediate drug release
US9655853B2 (en) 2012-02-28 2017-05-23 Grünenthal GmbH Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer
US10335373B2 (en) 2012-04-18 2019-07-02 Grunenthal Gmbh Tamper resistant and dose-dumping resistant pharmaceutical dosage form
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
JPWO2013187395A1 (ja) * 2012-06-12 2016-02-04 第一三共株式会社 容易な服用性と分割性を有する錠剤
JP2015096483A (ja) * 2012-06-12 2015-05-21 第一三共株式会社 容易な服用性と分割性を有する錠剤
JP2015063506A (ja) * 2012-06-12 2015-04-09 第一三共株式会社 容易な服用性と分割性を有する錠剤
WO2013187395A1 (ja) * 2012-06-12 2013-12-19 第一三共株式会社 容易な服用性と分割性を有する錠剤
US10154966B2 (en) 2013-05-29 2018-12-18 Grünenthal GmbH Tamper-resistant dosage form containing one or more particles
US9737490B2 (en) 2013-05-29 2017-08-22 Grünenthal GmbH Tamper resistant dosage form with bimodal release profile
US10624862B2 (en) 2013-07-12 2020-04-21 Grünenthal GmbH Tamper-resistant dosage form containing ethylene-vinyl acetate polymer
US10449547B2 (en) 2013-11-26 2019-10-22 Grünenthal GmbH Preparation of a powdery pharmaceutical composition by means of cryo-milling
JP5719479B1 (ja) * 2013-12-09 2015-05-20 第一三共株式会社 容易な分割性を有する錠剤
WO2015087561A1 (ja) * 2013-12-09 2015-06-18 第一三共株式会社 容易な分割性を有する錠剤
US9913814B2 (en) 2014-05-12 2018-03-13 Grünenthal GmbH Tamper resistant immediate release capsule formulation comprising tapentadol
US9872835B2 (en) 2014-05-26 2018-01-23 Grünenthal GmbH Multiparticles safeguarded against ethanolic dose-dumping
US9855263B2 (en) 2015-04-24 2018-01-02 Grünenthal GmbH Tamper-resistant dosage form with immediate release and resistance against solvent extraction
US10842750B2 (en) 2015-09-10 2020-11-24 Grünenthal GmbH Protecting oral overdose with abuse deterrent immediate release formulations

Also Published As

Publication number Publication date
CH648754A5 (en) 1985-04-15
BE884760A (fr) 1981-02-13
ZA805015B (en) 1981-08-26
JPS6361928B2 (Direct) 1988-11-30

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