JPS5653660A - 4-phenylphthalazine derivative - Google Patents
4-phenylphthalazine derivativeInfo
- Publication number
- JPS5653660A JPS5653660A JP13043479A JP13043479A JPS5653660A JP S5653660 A JPS5653660 A JP S5653660A JP 13043479 A JP13043479 A JP 13043479A JP 13043479 A JP13043479 A JP 13043479A JP S5653660 A JPS5653660 A JP S5653660A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- phenylphthalazine
- infarction
- cerebral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- KHIILJVSYUGMSE-UHFFFAOYSA-N 1-phenylphthalazine Chemical class C1=CC=CC=C1C1=NN=CC2=CC=CC=C12 KHIILJVSYUGMSE-UHFFFAOYSA-N 0.000 title 1
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 abstract 2
- 206010003210 Arteriosclerosis Diseases 0.000 abstract 1
- 206010008132 Cerebral thrombosis Diseases 0.000 abstract 1
- 206010061216 Infarction Diseases 0.000 abstract 1
- 201000001429 Intracranial Thrombosis Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000004448 alkyl carbonyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 208000011775 arteriosclerosis disease Diseases 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 230000000747 cardiac effect Effects 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 206010008118 cerebral infarction Diseases 0.000 abstract 1
- 208000026106 cerebrovascular disease Diseases 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000015271 coagulation Effects 0.000 abstract 1
- 238000005345 coagulation Methods 0.000 abstract 1
- -1 cyano, hydroxyl Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 230000007574 infarction Effects 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 239000011777 magnesium Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- IGUVJKICKDRMPR-UHFFFAOYSA-N n-(4-methylphenyl)-4-phenylphthalazin-1-amine Chemical compound C1=CC(C)=CC=C1NC(C1=CC=CC=C11)=NN=C1C1=CC=CC=C1 IGUVJKICKDRMPR-UHFFFAOYSA-N 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 229910000029 sodium carbonate Inorganic materials 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13043479A JPS5653660A (en) | 1979-10-09 | 1979-10-09 | 4-phenylphthalazine derivative |
| GB8030906A GB2063249A (en) | 1979-10-09 | 1980-09-25 | 4-Phenylphthalazine derivatives |
| NL8005411A NL8005411A (nl) | 1979-10-09 | 1980-09-30 | 4-fenylftalazinederivaten. |
| FR8021530A FR2468593A1 (fr) | 1979-10-09 | 1980-10-08 | Derives de 4-phenylphtalazine utilisables comme medicaments inhibiteurs de l'agregation de plaquettes sanguines, et procede pour leur preparation |
| IT25206/80A IT1148727B (it) | 1979-10-09 | 1980-10-08 | Derivati di 4-fenil-ftalazine ad azione terapeutica |
| DE19803038166 DE3038166A1 (de) | 1979-10-09 | 1980-10-09 | 4-phenylphthalazinderivate und verfahren zu deren herstellung, sowie arzneimittel, welche diese enthalten |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13043479A JPS5653660A (en) | 1979-10-09 | 1979-10-09 | 4-phenylphthalazine derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5653660A true JPS5653660A (en) | 1981-05-13 |
| JPS6242901B2 JPS6242901B2 (enrdf_load_stackoverflow) | 1987-09-10 |
Family
ID=15034137
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP13043479A Granted JPS5653660A (en) | 1979-10-09 | 1979-10-09 | 4-phenylphthalazine derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5653660A (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5324727A (en) * | 1991-09-26 | 1994-06-28 | Mitsubishi Chem Ind | 3,6-disubstituted pyridazine derivatives |
| EP0682947A1 (en) | 1994-05-19 | 1995-11-22 | Mitsubishi Chemical Corporation | Medicament for therapeutic and prophylactic treatment of diseases caused by smooth muscle cell hyperplasia |
-
1979
- 1979-10-09 JP JP13043479A patent/JPS5653660A/ja active Granted
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5324727A (en) * | 1991-09-26 | 1994-06-28 | Mitsubishi Chem Ind | 3,6-disubstituted pyridazine derivatives |
| US5462941A (en) * | 1991-09-26 | 1995-10-31 | Mitsubishi Chemical Corporation | 3,6-disubstituted pyradazine derivatives |
| EP0682947A1 (en) | 1994-05-19 | 1995-11-22 | Mitsubishi Chemical Corporation | Medicament for therapeutic and prophylactic treatment of diseases caused by smooth muscle cell hyperplasia |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6242901B2 (enrdf_load_stackoverflow) | 1987-09-10 |
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