JPS56500538A - - Google Patents
Info
- Publication number
- JPS56500538A JPS56500538A JP50127980A JP50127980A JPS56500538A JP S56500538 A JPS56500538 A JP S56500538A JP 50127980 A JP50127980 A JP 50127980A JP 50127980 A JP50127980 A JP 50127980A JP S56500538 A JPS56500538 A JP S56500538A
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/041,080 US4269777A (en) | 1979-05-21 | 1979-05-21 | Isotopically labeled vitamin D derivatives and processes for preparing same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS56500538A true JPS56500538A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1981-04-23 |
Family
ID=21914616
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50127980A Pending JPS56500538A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1979-05-21 | 1980-04-29 |
Country Status (9)
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5075465A (en) * | 1987-10-14 | 1991-12-24 | Toyo Jozo Kabushiki Kaisha | 25-hydroxy vitamin d3 derivatives, process for their production, and assay method using the same |
| US5202266A (en) * | 1987-10-14 | 1993-04-13 | Asahi Kasei Kogyo Kabushiki Kaisha | 25-hydroxy vitamin D3 derivatives, process for their production, and assay method using the same |
| JP2001504114A (ja) * | 1996-11-13 | 2001-03-27 | イムノダイアグノスティック システムズ リミティッド | ビタミンｄイムノアッセイシステム |
| JP2006526645A (ja) * | 2003-05-30 | 2006-11-24 | パーキンエルマー ラス インコーポレイテッド | 同位体標識した化学的に安定な試薬およびその合成方法 |
| JP2018519329A (ja) * | 2015-07-06 | 2018-07-19 | セージ セラピューティクス， インコーポレイテッド | オキシステロールおよびそれらの使用の方法 |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4360470A (en) * | 1980-10-22 | 1982-11-23 | Hoffmann-La Roche Inc. | Process and intermediates for the synthesis of Vitamin D3 metabolites and chenodeoxycholic acid |
| US4411833A (en) * | 1982-05-26 | 1983-10-25 | Wisconsin Alumni Research Foundation | Method for preparing 26,26,26,27,27,27-hexafluoro-1α,25-dihydroxycholesterol |
| US5036061A (en) * | 1983-05-09 | 1991-07-30 | Deluca Hector F | Process for the preparation of 1 alpha,25-dihydroxylated vitamin D2 and related compounds |
| WO1984004527A1 (en) * | 1983-05-09 | 1984-11-22 | Wisconsin Alumni Res Found | PROCESS FOR THE PREPARATION OF 1alpha,25-DIHYDROXYLATED VITAMIN D2 AND RELATED COMPOUNDS |
| US4585741A (en) * | 1983-08-25 | 1986-04-29 | Clevinger Brian L | Method of assay for vitamin D metabolites |
| US4661294A (en) * | 1985-03-18 | 1987-04-28 | The General Hospital Corporation | Biologically active 1-thio derivatives of vitamin D |
| US4898855A (en) * | 1987-09-14 | 1990-02-06 | Hoffman-La Roche Inc. | Deuterated analogs of 1,25-dihydroxycholecalciferol |
| US5247123A (en) * | 1987-09-14 | 1993-09-21 | Hoffmann-La Roche Inc. | Deuterated analogs of 1,25-dihydroxycholecalciferol |
| US5532228A (en) * | 1990-02-06 | 1996-07-02 | Schering Aktiengesellschaft | Side-chain homologous vitamin D derivatives, process for their production, pharmaceutical preparations containing these derivatives and their use as pharmaceutical agents |
| ATE444493T1 (de) * | 2002-07-12 | 2009-10-15 | Morehouse School Of Medicine | Verfahren zur identifikation von salzempfindlichen personen |
| ES2331289B2 (es) * | 2008-06-27 | 2010-06-25 | Universidade De Santiago De Compostela | Compuestos de la vitamina d deuterados. |
| JP5814247B2 (ja) * | 2009-10-02 | 2015-11-17 | ウィスコンシン・アルムニ・リサーチ・ファウンデーションＷｉｓｃｏｎｓｉｎ Ａｌｕｍｎｉ Ｒｅｓｅａｒｃｈ Ｆｏｕｎｄａｔｉｏｎ | １−デソキシ−２−メチレン−１９−ノル−ビタミンｄ類似体及びそれらの使用 |
| PL2753632T3 (pl) | 2011-09-08 | 2023-09-11 | Sage Therapeutics, Inc. | Neuroaktywne steroidy, kompozycje i ich zastosowanie |
| HUE055668T2 (hu) | 2013-03-13 | 2021-12-28 | Sage Therapeutics Inc | Neuroaktív szteroidok |
| WO2015195967A1 (en) | 2014-06-18 | 2015-12-23 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
| HRP20211282T1 (hr) | 2015-07-06 | 2021-11-12 | Sage Therapeutics, Inc. | Oksisteroli i postupci njihovog korištenja |
| KR102703602B1 (ko) | 2015-07-06 | 2024-09-06 | 세이지 테라퓨틱스, 인크. | 옥시스테롤 및 그의 사용 방법 |
| WO2017193046A1 (en) | 2016-05-06 | 2017-11-09 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
| TWI752976B (zh) | 2016-07-07 | 2022-01-21 | 美商賽吉醫療公司 | 氧固醇(oxysterol)及其使用方法 |
| MX392270B (es) | 2016-09-30 | 2025-03-24 | Sage Therapeutics Inc | Oxisteroles sustituidos en c7 y metodos de uso de los mismos. |
| MX2019004679A (es) | 2016-10-18 | 2019-10-15 | Sage Therapeutics Inc | Oxisteroles y metodos de uso de los mismos. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3833622A (en) * | 1969-03-17 | 1974-09-03 | Upjohn Co | Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds |
| FR2129011A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1971-03-11 | 1972-10-27 | Roussel Uclaf | |
| US4119647A (en) * | 1977-04-11 | 1978-10-10 | Hoffmann-La Roche Inc. | 25-Hydroxycholecalciferol-23,24-3 H and process for the preparation thereof |
| US4195027A (en) * | 1978-01-16 | 1980-03-25 | Wisconsin Alumni Research Foundation | Process for preparing 1α-hydroxylated compounds |
-
1979
- 1979-05-21 US US06/041,080 patent/US4269777A/en not_active Expired - Lifetime
-
1980
- 1980-04-29 DE DE3051094A patent/DE3051094C2/de not_active Expired
- 1980-04-29 JP JP50127980A patent/JPS56500538A/ja active Pending
- 1980-04-29 DE DE803045287T patent/DE3045287T1/de active Granted
- 1980-04-29 WO PCT/US1980/000493 patent/WO1980002562A1/en active Application Filing
- 1980-04-30 CA CA000350960A patent/CA1152488A/en not_active Expired
- 1980-05-12 IL IL60055A patent/IL60055A/xx unknown
- 1980-05-12 IL IL69420A patent/IL69420A/xx unknown
- 1980-05-20 GB GB8123418A patent/GB2077736B/en not_active Expired
- 1980-05-20 GB GB8130231A patent/GB2083043B/en not_active Expired
- 1980-05-20 GB GB8130232A patent/GB2082587B/en not_active Expired
- 1980-05-20 GB GB8016584A patent/GB2052509B/en not_active Expired
- 1980-05-21 IE IE2996/83A patent/IE50426B1/en not_active IP Right Cessation
- 1980-05-21 IE IE2995/83A patent/IE50425B1/en not_active IP Right Cessation
- 1980-05-21 IE IE1058/80A patent/IE50424B1/en not_active IP Right Cessation
- 1980-05-21 FR FR8011385A patent/FR2457283A1/fr active Granted
-
1981
- 1981-01-23 FR FR8101332A patent/FR2479214A1/fr active Granted
- 1981-09-02 FR FR8116732A patent/FR2485022A1/fr active Granted
-
1983
- 1983-08-03 IL IL69420A patent/IL69420A0/xx unknown
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5075465A (en) * | 1987-10-14 | 1991-12-24 | Toyo Jozo Kabushiki Kaisha | 25-hydroxy vitamin d3 derivatives, process for their production, and assay method using the same |
| US5202266A (en) * | 1987-10-14 | 1993-04-13 | Asahi Kasei Kogyo Kabushiki Kaisha | 25-hydroxy vitamin D3 derivatives, process for their production, and assay method using the same |
| JP2001504114A (ja) * | 1996-11-13 | 2001-03-27 | イムノダイアグノスティック システムズ リミティッド | ビタミンｄイムノアッセイシステム |
| JP2006526645A (ja) * | 2003-05-30 | 2006-11-24 | パーキンエルマー ラス インコーポレイテッド | 同位体標識した化学的に安定な試薬およびその合成方法 |
| US8058464B2 (en) | 2003-05-30 | 2011-11-15 | Perkinelmer Health Sciences, Inc. | Isotopically labeled chemically stable reagents and process for the synthesis thereof |
| JP2018519329A (ja) * | 2015-07-06 | 2018-07-19 | セージ セラピューティクス， インコーポレイテッド | オキシステロールおよびそれらの使用の方法 |
| JP2021063118A (ja) * | 2015-07-06 | 2021-04-22 | セージ セラピューティクス， インコーポレイテッド | オキシステロールおよびそれらの使用の方法 |