JPS5649396A - Novel muramyldipeptide derivative - Google Patents
Novel muramyldipeptide derivativeInfo
- Publication number
- JPS5649396A JPS5649396A JP12501979A JP12501979A JPS5649396A JP S5649396 A JPS5649396 A JP S5649396A JP 12501979 A JP12501979 A JP 12501979A JP 12501979 A JP12501979 A JP 12501979A JP S5649396 A JPS5649396 A JP S5649396A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- alanine
- compound
- acid residue
- medium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- BSOQXXWZTUDTEL-ZUYCGGNHSA-N muramyl dipeptide Chemical class OC(=O)CC[C@H](C(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](C)O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](O)[C@@H]1NC(C)=O BSOQXXWZTUDTEL-ZUYCGGNHSA-N 0.000 title abstract 2
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 3
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 abstract 2
- QNAYBMKLOCPYGJ-UHFFFAOYSA-N D-alpha-Ala Natural products CC([NH3+])C([O-])=O QNAYBMKLOCPYGJ-UHFFFAOYSA-N 0.000 abstract 2
- QNAYBMKLOCPYGJ-UWTATZPHSA-N L-Alanine Natural products C[C@@H](N)C(O)=O QNAYBMKLOCPYGJ-UWTATZPHSA-N 0.000 abstract 2
- 229960003767 alanine Drugs 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 108010042708 Acetylmuramyl-Alanyl-Isoglutamine Proteins 0.000 abstract 1
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 abstract 1
- 125000003412 L-alanyl group Chemical group [H]N([H])[C@@](C([H])([H])[H])(C(=O)[*])[H] 0.000 abstract 1
- -1 N-Acetylmuramyl-L-alanyl-D-isoglutamine octyl ester Chemical class 0.000 abstract 1
- NQTADLQHYWFPDB-UHFFFAOYSA-N N-Hydroxysuccinimide Chemical compound ON1C(=O)CCC1=O NQTADLQHYWFPDB-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 125000001301 ethoxy group Chemical group [H]C([H])([H])C([H])([H])O* 0.000 abstract 1
- 125000005313 fatty acid group Chemical group 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 125000002572 propoxy group Chemical group [*]OC([H])([H])C(C([H])([H])[H])([H])[H] 0.000 abstract 1
- 229960001153 serine Drugs 0.000 abstract 1
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12501979A JPS5649396A (en) | 1979-09-28 | 1979-09-28 | Novel muramyldipeptide derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12501979A JPS5649396A (en) | 1979-09-28 | 1979-09-28 | Novel muramyldipeptide derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5649396A true JPS5649396A (en) | 1981-05-02 |
| JPS6312879B2 JPS6312879B2 (enrdf_load_stackoverflow) | 1988-03-23 |
Family
ID=14899838
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP12501979A Granted JPS5649396A (en) | 1979-09-28 | 1979-09-28 | Novel muramyldipeptide derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5649396A (enrdf_load_stackoverflow) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58188891A (ja) * | 1982-04-14 | 1983-11-04 | バイエル・アクチエンゲゼルシヤフト | Ｎ―グリコシルカルボキサミド誘導体、その製造方法及び該誘導体を含有する抗感染力強化剤 |
| JPS59172497A (ja) * | 1983-03-22 | 1984-09-29 | Dai Ichi Seiyaku Co Ltd | 新規ムラミルペプチド誘導体 |
| JPS61275299A (ja) * | 1985-05-29 | 1986-12-05 | Akira Hasegawa | デオキシムラミルジペプチド誘導体 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5273820A (en) * | 1975-12-10 | 1977-06-21 | Ciba Geigy Ag | Glucosamine derivative and its method of manufacturing |
-
1979
- 1979-09-28 JP JP12501979A patent/JPS5649396A/ja active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5273820A (en) * | 1975-12-10 | 1977-06-21 | Ciba Geigy Ag | Glucosamine derivative and its method of manufacturing |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58188891A (ja) * | 1982-04-14 | 1983-11-04 | バイエル・アクチエンゲゼルシヤフト | Ｎ―グリコシルカルボキサミド誘導体、その製造方法及び該誘導体を含有する抗感染力強化剤 |
| JPS59172497A (ja) * | 1983-03-22 | 1984-09-29 | Dai Ichi Seiyaku Co Ltd | 新規ムラミルペプチド誘導体 |
| JPS61275299A (ja) * | 1985-05-29 | 1986-12-05 | Akira Hasegawa | デオキシムラミルジペプチド誘導体 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6312879B2 (enrdf_load_stackoverflow) | 1988-03-23 |
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