JPS5643250A - Preparation of substituted phenylacetic acid or its salt - Google Patents
Preparation of substituted phenylacetic acid or its saltInfo
- Publication number
- JPS5643250A JPS5643250A JP12054579A JP12054579A JPS5643250A JP S5643250 A JPS5643250 A JP S5643250A JP 12054579 A JP12054579 A JP 12054579A JP 12054579 A JP12054579 A JP 12054579A JP S5643250 A JPS5643250 A JP S5643250A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- nah
- alkali
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: To prepare the titled compound in high yield, with simple procedure, by reacting an anthranylaldehyde derivative with dimethylaminomethylene diphosphonate derivative in the presence of NaH, and hydrolyzing the product in the presence of an alkali.
CONSTITUTION: A compound of formula I is made to react with a compound of formula II (R is lower alkyl) in the presence of NaH, pref. in a reaction solvent such as dioxane, etc., at 40W80°C. The amounts of the compound of formula II and NaH are not less than equivalent to the amount of the compound formula. The resulting compounds of formula III and formula IV are hydrolyzed in the presence of an alkali (e.g. NaOH, etc.) to afford the objective compound of formula V. The compound of formula II which is one of the starting materials, is obtained by heating dimethylformamide dimethylacetal (1mol) with diethyl phosphite (2mol) at 60W80°C for a short time, and distilling the reaction product under reduced pressure.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12054579A JPS5643250A (en) | 1979-09-19 | 1979-09-19 | Preparation of substituted phenylacetic acid or its salt |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12054579A JPS5643250A (en) | 1979-09-19 | 1979-09-19 | Preparation of substituted phenylacetic acid or its salt |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5643250A true JPS5643250A (en) | 1981-04-21 |
Family
ID=14788945
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP12054579A Pending JPS5643250A (en) | 1979-09-19 | 1979-09-19 | Preparation of substituted phenylacetic acid or its salt |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5643250A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60101121A (en) * | 1983-10-12 | 1985-06-05 | チバ‐ガイギー アクチエンゲゼルシヤフト | Radiation-reactive polycondensate, manufacture, coated material and use |
| US20180118769A1 (en) * | 2015-06-23 | 2018-05-03 | University Of Oregon | Phosphorus-containing heterocycles and a method for making and using |
-
1979
- 1979-09-19 JP JP12054579A patent/JPS5643250A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60101121A (en) * | 1983-10-12 | 1985-06-05 | チバ‐ガイギー アクチエンゲゼルシヤフト | Radiation-reactive polycondensate, manufacture, coated material and use |
| US20180118769A1 (en) * | 2015-06-23 | 2018-05-03 | University Of Oregon | Phosphorus-containing heterocycles and a method for making and using |
| US10556920B2 (en) * | 2015-06-23 | 2020-02-11 | University Of Oregon | Phosphorus-containing heterocycles and a method for making and using |
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