JPS5640698A - Preparation of fortimicin a - Google Patents
Preparation of fortimicin aInfo
- Publication number
- JPS5640698A JPS5640698A JP11667679A JP11667679A JPS5640698A JP S5640698 A JPS5640698 A JP S5640698A JP 11667679 A JP11667679 A JP 11667679A JP 11667679 A JP11667679 A JP 11667679A JP S5640698 A JPS5640698 A JP S5640698A
- Authority
- JP
- Japan
- Prior art keywords
- fortimicin
- formula
- antibiotic substance
- substance
- gram
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Saccharide Compounds (AREA)
Abstract
PURPOSE: To prepare an antibiotic substance, fortimicin A, effective to Gram- positive and Gram-negative bacteria including those resistant to kanamycin and gentamicin, in high yield, by treating a novel aminoglycoside antibiotic substance SF-2052 substance with a base.
CONSTITUTION: A novel aminoglycoside antibiotic substance, SF-2052 of formula I is treated with a base such as caustic soda, trimethylamine, etc. pref. in a reaction solvent such as water, at 20W70°C for 1W20hr to obtain the objective fortimicin A of formula II. The starting antibiotic substance of formula I is prepared, e.g. by culturing Dactylosporangium matsuzakiense SF-2052 strain (FERM-P No.5073).
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11667679A JPS5640698A (en) | 1979-09-13 | 1979-09-13 | Preparation of fortimicin a |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11667679A JPS5640698A (en) | 1979-09-13 | 1979-09-13 | Preparation of fortimicin a |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5640698A true JPS5640698A (en) | 1981-04-16 |
JPS631947B2 JPS631947B2 (en) | 1988-01-14 |
Family
ID=14693117
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP11667679A Granted JPS5640698A (en) | 1979-09-13 | 1979-09-13 | Preparation of fortimicin a |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5640698A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH07277395A (en) * | 1994-04-04 | 1995-10-24 | Yoshikatsu Fujiwara | Mobile silo for cement or the like |
-
1979
- 1979-09-13 JP JP11667679A patent/JPS5640698A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH07277395A (en) * | 1994-04-04 | 1995-10-24 | Yoshikatsu Fujiwara | Mobile silo for cement or the like |
Also Published As
Publication number | Publication date |
---|---|
JPS631947B2 (en) | 1988-01-14 |
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