JPS5640698A - Preparation of fortimicin a - Google Patents

Preparation of fortimicin a

Info

Publication number
JPS5640698A
JPS5640698A JP11667679A JP11667679A JPS5640698A JP S5640698 A JPS5640698 A JP S5640698A JP 11667679 A JP11667679 A JP 11667679A JP 11667679 A JP11667679 A JP 11667679A JP S5640698 A JPS5640698 A JP S5640698A
Authority
JP
Japan
Prior art keywords
fortimicin
formula
antibiotic substance
substance
gram
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP11667679A
Other languages
Japanese (ja)
Other versions
JPS631947B2 (en
Inventor
Kazunori Oba
Takashi Tsuruoka
Norio Ezaki
Yasumitsu Kondo
Tomizo Niwa
Shigeharu Inoue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meiji Seika Kaisha Ltd
Original Assignee
Meiji Seika Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Seika Kaisha Ltd filed Critical Meiji Seika Kaisha Ltd
Priority to JP11667679A priority Critical patent/JPS5640698A/en
Publication of JPS5640698A publication Critical patent/JPS5640698A/en
Publication of JPS631947B2 publication Critical patent/JPS631947B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Saccharide Compounds (AREA)

Abstract

PURPOSE: To prepare an antibiotic substance, fortimicin A, effective to Gram- positive and Gram-negative bacteria including those resistant to kanamycin and gentamicin, in high yield, by treating a novel aminoglycoside antibiotic substance SF-2052 substance with a base.
CONSTITUTION: A novel aminoglycoside antibiotic substance, SF-2052 of formula I is treated with a base such as caustic soda, trimethylamine, etc. pref. in a reaction solvent such as water, at 20W70°C for 1W20hr to obtain the objective fortimicin A of formula II. The starting antibiotic substance of formula I is prepared, e.g. by culturing Dactylosporangium matsuzakiense SF-2052 strain (FERM-P No.5073).
COPYRIGHT: (C)1981,JPO&Japio
JP11667679A 1979-09-13 1979-09-13 Preparation of fortimicin a Granted JPS5640698A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP11667679A JPS5640698A (en) 1979-09-13 1979-09-13 Preparation of fortimicin a

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11667679A JPS5640698A (en) 1979-09-13 1979-09-13 Preparation of fortimicin a

Publications (2)

Publication Number Publication Date
JPS5640698A true JPS5640698A (en) 1981-04-16
JPS631947B2 JPS631947B2 (en) 1988-01-14

Family

ID=14693117

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11667679A Granted JPS5640698A (en) 1979-09-13 1979-09-13 Preparation of fortimicin a

Country Status (1)

Country Link
JP (1) JPS5640698A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07277395A (en) * 1994-04-04 1995-10-24 Yoshikatsu Fujiwara Mobile silo for cement or the like

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07277395A (en) * 1994-04-04 1995-10-24 Yoshikatsu Fujiwara Mobile silo for cement or the like

Also Published As

Publication number Publication date
JPS631947B2 (en) 1988-01-14

Similar Documents

Publication Publication Date Title
JPS5495548A (en) Fortimicin ae and its preparation
JPS5640698A (en) Preparation of fortimicin a
JPS5543012A (en) Novel anthracycline derivatine and its preparation
US4145253A (en) Process for producing fortimicin factors
Yasuzawa et al. CV-1, a new antibiotic produced by a strain of Streptomyces sp. II. structure determination
US3939043A (en) Antibiotics designated XK-88 series and process for production thereof
JPS5585552A (en) New lactyltetrapeptide
GB1473178A (en) Preparation of garamine and tri-n-substituted garamine and intermediates produced thereby
JPS5498741A (en) Novel antibiotic and its preparation
US4045610A (en) Antibiotics designated xk-88 series
JPS5640699A (en) Preparation of fortimicin b
US4097428A (en) Fortimicin C and process for production thereof
GB2019388A (en) Antibiotic DC-11 and process for production thereof
JPS5643295A (en) Istamycin ao and/or istamycin bo, and their preparation
JPS5620598A (en) Novel antibiotic and its preparation
JPS54160795A (en) Preparation of gentamicin c/a
JPS55118490A (en) Demethylmaytansinoid compound and its preparation
JPS55162790A (en) Novel fortimicin compound and its preparation
JPS55149297A (en) Antibiotic herbicidin c, e, f, and g and its preparation
JPS5640697A (en) Sf-2052b substance and its preparation
JPS5452797A (en) Novel antibiotic substance bn-200, and its preparation
JPS5498793A (en) Deacylated antibiotic and its preparation
JPS55100395A (en) Novel substance tpj-b and its preparation
JPS5785399A (en) Antibiotic yt-3927 and its preparation
JPS5462393A (en) Preparation of antibiotic substance, verdamicin