JPS5616446A - Novel derivative of terephthalic acid and its preparation - Google Patents
Novel derivative of terephthalic acid and its preparationInfo
- Publication number
- JPS5616446A JPS5616446A JP9031579A JP9031579A JPS5616446A JP S5616446 A JPS5616446 A JP S5616446A JP 9031579 A JP9031579 A JP 9031579A JP 9031579 A JP9031579 A JP 9031579A JP S5616446 A JPS5616446 A JP S5616446A
- Authority
- JP
- Japan
- Prior art keywords
- preparation
- methoxy
- compound
- formula
- terephthalic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:A 2-methoxy-5-haloterephthalic acid-1-alkyl ester of formula I (R is lower alkyl; X is halogen).
EXAMPLE: 2-Methoxy-5-chloroterephthalic acid-1-methyl ester.
USE: An intermediate for the preparation of pharmaceuticals. Usable for the preparation of 2-methoxy-4-amino-5-chloro-N-(tertiary aminoethyl) benzamide etc. of the pharmaceuticals having pharmacological actions, e.g. analgesic, sedative, neuroleptic and mental hypotonic actions.
PROCESS: The compound of formula I is obtained by the reaction of a compound of formula II in a solvent, e.g. methanol, in the presence of an acid catalyst (e.g. H2 SO4 or HCl) or by the reaction of the compound with diazomethane or an alkyl halide in a solvent, e.g. acetone or benzene.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9031579A JPS5616446A (en) | 1979-07-18 | 1979-07-18 | Novel derivative of terephthalic acid and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9031579A JPS5616446A (en) | 1979-07-18 | 1979-07-18 | Novel derivative of terephthalic acid and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5616446A true JPS5616446A (en) | 1981-02-17 |
JPS623831B2 JPS623831B2 (en) | 1987-01-27 |
Family
ID=13995088
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP9031579A Granted JPS5616446A (en) | 1979-07-18 | 1979-07-18 | Novel derivative of terephthalic acid and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5616446A (en) |
-
1979
- 1979-07-18 JP JP9031579A patent/JPS5616446A/en active Granted
Non-Patent Citations (1)
Title |
---|
CHEM PHARM BULL * |
Also Published As
Publication number | Publication date |
---|---|
JPS623831B2 (en) | 1987-01-27 |
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