JPS5616445A - Novel derivative of terephthalic acid and its preparation - Google Patents
Novel derivative of terephthalic acid and its preparationInfo
- Publication number
- JPS5616445A JPS5616445A JP9031479A JP9031479A JPS5616445A JP S5616445 A JPS5616445 A JP S5616445A JP 9031479 A JP9031479 A JP 9031479A JP 9031479 A JP9031479 A JP 9031479A JP S5616445 A JPS5616445 A JP S5616445A
- Authority
- JP
- Japan
- Prior art keywords
- methoxy
- preparation
- acid
- formula
- ester
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:A 2-methoxy-5-haloterephthalic acid-4-alkyl ester of formula I (R is lower alkyl; X is halogen).
EXAMPLE: 2-Methoxy-5-chloroterephthalic acid-4-methyl ester.
USE: An intermediate for the preparation of pharmaceuticals. Usable for the preparation of 2-methoxy-4-amino-5-chloro-N-(tertiary aminoethyl)benzamide etc. of the pharmaceuticals having pharmacological actions, e.g. analgesic, sedative, neuroleptic and mental hypotonic actions.
PROCESS: The compound of formula I is obtained by the selective hydrolysis of the carboxylic acid ester at the 1-position of a 2-methoxy-5-haloterephthalic acid-1,4- dialkyl ester of formula II (R'is alkyl) in water or a solvent, e.g. a lower alcohol, in the presence of a base (e.g. NaOH or KOH).
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9031479A JPS5616445A (en) | 1979-07-18 | 1979-07-18 | Novel derivative of terephthalic acid and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9031479A JPS5616445A (en) | 1979-07-18 | 1979-07-18 | Novel derivative of terephthalic acid and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5616445A true JPS5616445A (en) | 1981-02-17 |
JPS623830B2 JPS623830B2 (en) | 1987-01-27 |
Family
ID=13995059
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP9031479A Granted JPS5616445A (en) | 1979-07-18 | 1979-07-18 | Novel derivative of terephthalic acid and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5616445A (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102173885B1 (en) * | 2020-03-04 | 2020-11-04 | 이원익 | Device working cold medium pipe for aircondisioner scondensers |
-
1979
- 1979-07-18 JP JP9031479A patent/JPS5616445A/en active Granted
Non-Patent Citations (1)
Title |
---|
CHEM PHARM BULL * |
Also Published As
Publication number | Publication date |
---|---|
JPS623830B2 (en) | 1987-01-27 |
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