JPS56161385A - Ester derivative - Google Patents

Ester derivative

Info

Publication number
JPS56161385A
JPS56161385A JP6396980A JP6396980A JPS56161385A JP S56161385 A JPS56161385 A JP S56161385A JP 6396980 A JP6396980 A JP 6396980A JP 6396980 A JP6396980 A JP 6396980A JP S56161385 A JPS56161385 A JP S56161385A
Authority
JP
Japan
Prior art keywords
remedy
expressed
formula
agent useful
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP6396980A
Other languages
Japanese (ja)
Other versions
JPS648630B2 (en
Inventor
Setsuo Fujii
Masateru Kurumi
Toyoo Nakayama
Ryoji Matsui
Toshiyuki Okutome
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Torii Pharmaceutical Co Ltd
Original Assignee
Torii Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Torii Pharmaceutical Co Ltd filed Critical Torii Pharmaceutical Co Ltd
Priority to JP6396980A priority Critical patent/JPS56161385A/en
Publication of JPS56161385A publication Critical patent/JPS56161385A/en
Publication of JPS648630B2 publication Critical patent/JPS648630B2/ja
Granted legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A 4-amidinophenyl ester of piperonylic acid expressed by formula I and an acid addition salt thereof usable as a medicine.
USE: An anticomplementary agent useful as the remedy for allergic diseases, e.g. nephritis, an antitrypsin agent useful as the remedy for pancreatitis, etc., an antiplasmin agent or anticallicrein agent useful as the remedy for hemorrhagic diseases, and an antithrombin agent useful as the remedy for thrombosis, etc.
PROCESS: A piperonyl halide expressed by formula II (X is halogen, preferably Cl) is reacted with 4-amidinophenol expressed by formula III in the presence of a dehydrohalogenating agent to give the compound expressed by formula I, and if desired the resultant compound is converted into an acid addition salt thereof as a medicine. The compound has a high stability in blood in spite of an ester bond in structure.
COPYRIGHT: (C)1981,JPO&Japio
JP6396980A 1980-05-16 1980-05-16 Ester derivative Granted JPS56161385A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP6396980A JPS56161385A (en) 1980-05-16 1980-05-16 Ester derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6396980A JPS56161385A (en) 1980-05-16 1980-05-16 Ester derivative

Publications (2)

Publication Number Publication Date
JPS56161385A true JPS56161385A (en) 1981-12-11
JPS648630B2 JPS648630B2 (en) 1989-02-14

Family

ID=13244622

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6396980A Granted JPS56161385A (en) 1980-05-16 1980-05-16 Ester derivative

Country Status (1)

Country Link
JP (1) JPS56161385A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8609715B2 (en) 2009-12-07 2013-12-17 Ajinomoto Co., Inc. Heteroarylcarboxylic acid ester derivative

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8609715B2 (en) 2009-12-07 2013-12-17 Ajinomoto Co., Inc. Heteroarylcarboxylic acid ester derivative
US8877805B2 (en) 2009-12-07 2014-11-04 Ajinomoto Co., Inc. Heteroarylcarboxylic acid ester derivative
US9115107B2 (en) 2009-12-07 2015-08-25 Ajinomoto Co., Inc. Heteroarylcarboxylic acid ester derivative

Also Published As

Publication number Publication date
JPS648630B2 (en) 1989-02-14

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