JPS56161385A - Ester derivative - Google Patents
Ester derivativeInfo
- Publication number
- JPS56161385A JPS56161385A JP6396980A JP6396980A JPS56161385A JP S56161385 A JPS56161385 A JP S56161385A JP 6396980 A JP6396980 A JP 6396980A JP 6396980 A JP6396980 A JP 6396980A JP S56161385 A JPS56161385 A JP S56161385A
- Authority
- JP
- Japan
- Prior art keywords
- remedy
- expressed
- formula
- agent useful
- agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A 4-amidinophenyl ester of piperonylic acid expressed by formula I and an acid addition salt thereof usable as a medicine.
USE: An anticomplementary agent useful as the remedy for allergic diseases, e.g. nephritis, an antitrypsin agent useful as the remedy for pancreatitis, etc., an antiplasmin agent or anticallicrein agent useful as the remedy for hemorrhagic diseases, and an antithrombin agent useful as the remedy for thrombosis, etc.
PROCESS: A piperonyl halide expressed by formula II (X is halogen, preferably Cl) is reacted with 4-amidinophenol expressed by formula III in the presence of a dehydrohalogenating agent to give the compound expressed by formula I, and if desired the resultant compound is converted into an acid addition salt thereof as a medicine. The compound has a high stability in blood in spite of an ester bond in structure.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6396980A JPS56161385A (en) | 1980-05-16 | 1980-05-16 | Ester derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6396980A JPS56161385A (en) | 1980-05-16 | 1980-05-16 | Ester derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56161385A true JPS56161385A (en) | 1981-12-11 |
JPS648630B2 JPS648630B2 (en) | 1989-02-14 |
Family
ID=13244622
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP6396980A Granted JPS56161385A (en) | 1980-05-16 | 1980-05-16 | Ester derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56161385A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8609715B2 (en) | 2009-12-07 | 2013-12-17 | Ajinomoto Co., Inc. | Heteroarylcarboxylic acid ester derivative |
-
1980
- 1980-05-16 JP JP6396980A patent/JPS56161385A/en active Granted
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8609715B2 (en) | 2009-12-07 | 2013-12-17 | Ajinomoto Co., Inc. | Heteroarylcarboxylic acid ester derivative |
US8877805B2 (en) | 2009-12-07 | 2014-11-04 | Ajinomoto Co., Inc. | Heteroarylcarboxylic acid ester derivative |
US9115107B2 (en) | 2009-12-07 | 2015-08-25 | Ajinomoto Co., Inc. | Heteroarylcarboxylic acid ester derivative |
Also Published As
Publication number | Publication date |
---|---|
JPS648630B2 (en) | 1989-02-14 |
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