JPS5615281A - Cembranolide diterpens - Google Patents
Cembranolide diterpensInfo
- Publication number
- JPS5615281A JPS5615281A JP9082079A JP9082079A JPS5615281A JP S5615281 A JPS5615281 A JP S5615281A JP 9082079 A JP9082079 A JP 9082079A JP 9082079 A JP9082079 A JP 9082079A JP S5615281 A JPS5615281 A JP S5615281A
- Authority
- JP
- Japan
- Prior art keywords
- extracted
- acetone
- eluted
- hexane
- cembranolide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Furan Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A carbon 13-membered ring cembranolide diterpen shown by the formula I (R' is H or lower alkanoyl; when R' is H, X is H2 and when R' is lower alkanoyl, X is O) or II (R" is lower alkoxy).
USE: A drug having antitumor action, hypotensive action, etc. Especially carcinostatic agent.
PROCESS: Lobophytum pauciflorum (Ehrenberg) is chopped into slices in an organic solvent, and extracted with methanol and acetone successively. Both the extracted solutions are dispersed in water and extracted with ether. The ether soluble part is subjected to silica gel chromatography, eluted with n-hexane-acetone (in a weight ratio of 20:1W1:1), and fractioned. An n-hexane-acetone (5:1) soluble part is further subjected to silica gel chromatography and eluted with ethyl acetate (20:1W 10:1) to give a crystalline substance shown by the formula I wherein R' is acetyl and X is H2.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9082079A JPS5615281A (en) | 1979-07-16 | 1979-07-16 | Cembranolide diterpens |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9082079A JPS5615281A (en) | 1979-07-16 | 1979-07-16 | Cembranolide diterpens |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5615281A true JPS5615281A (en) | 1981-02-14 |
Family
ID=14009223
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9082079A Pending JPS5615281A (en) | 1979-07-16 | 1979-07-16 | Cembranolide diterpens |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5615281A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61209089A (en) * | 1985-03-09 | 1986-09-17 | Shimizu Constr Co Ltd | Method and apparatus for treating organic waste water |
| EP0258082A2 (en) * | 1986-07-10 | 1988-03-02 | Mitsubishi Kasei Corporation | Anti-solid tumor agents |
| US4822532A (en) * | 1982-09-01 | 1989-04-18 | Aisan Kogyo Kabushiki Kaisha | Carburetor |
| US5374352A (en) * | 1993-04-02 | 1994-12-20 | Pattee; Harley J. | Universal recycled wash water system |
| WO2010109687A1 (en) * | 2009-03-24 | 2010-09-30 | 国立大学法人九州大学 | Coral-derived therapeutic agent for inflammations and allergic diseases |
-
1979
- 1979-07-16 JP JP9082079A patent/JPS5615281A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4822532A (en) * | 1982-09-01 | 1989-04-18 | Aisan Kogyo Kabushiki Kaisha | Carburetor |
| JPS61209089A (en) * | 1985-03-09 | 1986-09-17 | Shimizu Constr Co Ltd | Method and apparatus for treating organic waste water |
| EP0258082A2 (en) * | 1986-07-10 | 1988-03-02 | Mitsubishi Kasei Corporation | Anti-solid tumor agents |
| US5374352A (en) * | 1993-04-02 | 1994-12-20 | Pattee; Harley J. | Universal recycled wash water system |
| US5445730A (en) * | 1993-04-02 | 1995-08-29 | Pattee; Harley J. | Grease/oil/water separator device for vehicle wash system |
| WO2010109687A1 (en) * | 2009-03-24 | 2010-09-30 | 国立大学法人九州大学 | Coral-derived therapeutic agent for inflammations and allergic diseases |
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