JPS56108719A - Novel antibiotic antlermicin b and c, and their preparation - Google Patents

Novel antibiotic antlermicin b and c, and their preparation

Info

Publication number
JPS56108719A
JPS56108719A JP1020980A JP1020980A JPS56108719A JP S56108719 A JPS56108719 A JP S56108719A JP 1020980 A JP1020980 A JP 1020980A JP 1020980 A JP1020980 A JP 1020980A JP S56108719 A JPS56108719 A JP S56108719A
Authority
JP
Japan
Prior art keywords
antlermicin
methanol
preparation
soluble
antibiotic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1020980A
Other languages
Japanese (ja)
Other versions
JPS5734997B2 (en
Inventor
Kiyoshi Isono
Masakazu Uramoto
Kimie Obinata
Taku Mizuno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RIKEN Institute of Physical and Chemical Research
Original Assignee
RIKEN Institute of Physical and Chemical Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RIKEN Institute of Physical and Chemical Research filed Critical RIKEN Institute of Physical and Chemical Research
Priority to JP1020980A priority Critical patent/JPS56108719A/en
Publication of JPS56108719A publication Critical patent/JPS56108719A/en
Publication of JPS5734997B2 publication Critical patent/JPS5734997B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

NEW MATERIAL:Antibiotic antlermicin B and C (B and C for short respectively. Appearance: white powder. Elemental analysis: B, C 60.60%, H 7.24%, N 2.18% and C, C 60.71%, H 7.16%, N 2.77%. Molecular weight: B, 1,260, and C, 930. Melting point: B, 210W214°C, and C, 229W236°C. Specific rotary power: B, [α]d 21-67.1° (C=0.63, methanol), and C, [α]d 21-71.3° (C=0.62, methanol). Solubility: soluble in methanol, acetone, etc., slightly soluble in petroleum ether or water. Acidic substances.
USE: Antibacterial agent, and carcinostatic agent. Having activities against Gram- positive bacilli, cancer cells, etc.
PROCESS: A new strain T-90 (FERM P 5005) of Micromonospora chalcea is subjected to neutral cultivation under aerobic conditions, the desired substance is extracted with an organic solvent, e.g., ethyl acetate, etc., and purifed by extraction, etc., to give antlermicin B and C.
COPYRIGHT: (C)1981,JPO&Japio
JP1020980A 1980-01-31 1980-01-31 Novel antibiotic antlermicin b and c, and their preparation Granted JPS56108719A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP1020980A JPS56108719A (en) 1980-01-31 1980-01-31 Novel antibiotic antlermicin b and c, and their preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1020980A JPS56108719A (en) 1980-01-31 1980-01-31 Novel antibiotic antlermicin b and c, and their preparation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP56193580A Division JPS57144984A (en) 1981-11-30 1981-11-30 Novel antibiotic antlermicin c and its preparation

Publications (2)

Publication Number Publication Date
JPS56108719A true JPS56108719A (en) 1981-08-28
JPS5734997B2 JPS5734997B2 (en) 1982-07-26

Family

ID=11743875

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1020980A Granted JPS56108719A (en) 1980-01-31 1980-01-31 Novel antibiotic antlermicin b and c, and their preparation

Country Status (1)

Country Link
JP (1) JPS56108719A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6548536B2 (en) 1998-08-31 2003-04-15 Kyowa Hakko Kogyo Co., Ltd. Agent for inducing apoptosis

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6373894U (en) * 1986-10-31 1988-05-17

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6548536B2 (en) 1998-08-31 2003-04-15 Kyowa Hakko Kogyo Co., Ltd. Agent for inducing apoptosis

Also Published As

Publication number Publication date
JPS5734997B2 (en) 1982-07-26

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