JPS56108719A - Novel antibiotic antlermicin b and c, and their preparation - Google Patents
Novel antibiotic antlermicin b and c, and their preparationInfo
- Publication number
- JPS56108719A JPS56108719A JP1020980A JP1020980A JPS56108719A JP S56108719 A JPS56108719 A JP S56108719A JP 1020980 A JP1020980 A JP 1020980A JP 1020980 A JP1020980 A JP 1020980A JP S56108719 A JPS56108719 A JP S56108719A
- Authority
- JP
- Japan
- Prior art keywords
- antlermicin
- methanol
- preparation
- soluble
- antibiotic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
Abstract
NEW MATERIAL:Antibiotic antlermicin B and C (B and C for short respectively. Appearance: white powder. Elemental analysis: B, C 60.60%, H 7.24%, N 2.18% and C, C 60.71%, H 7.16%, N 2.77%. Molecular weight: B, 1,260, and C, 930. Melting point: B, 210W214°C, and C, 229W236°C. Specific rotary power: B, [α]d 21-67.1° (C=0.63, methanol), and C, [α]d 21-71.3° (C=0.62, methanol). Solubility: soluble in methanol, acetone, etc., slightly soluble in petroleum ether or water. Acidic substances.
USE: Antibacterial agent, and carcinostatic agent. Having activities against Gram- positive bacilli, cancer cells, etc.
PROCESS: A new strain T-90 (FERM P 5005) of Micromonospora chalcea is subjected to neutral cultivation under aerobic conditions, the desired substance is extracted with an organic solvent, e.g., ethyl acetate, etc., and purifed by extraction, etc., to give antlermicin B and C.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1020980A JPS56108719A (en) | 1980-01-31 | 1980-01-31 | Novel antibiotic antlermicin b and c, and their preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1020980A JPS56108719A (en) | 1980-01-31 | 1980-01-31 | Novel antibiotic antlermicin b and c, and their preparation |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56193580A Division JPS57144984A (en) | 1981-11-30 | 1981-11-30 | Novel antibiotic antlermicin c and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56108719A true JPS56108719A (en) | 1981-08-28 |
JPS5734997B2 JPS5734997B2 (en) | 1982-07-26 |
Family
ID=11743875
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1020980A Granted JPS56108719A (en) | 1980-01-31 | 1980-01-31 | Novel antibiotic antlermicin b and c, and their preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56108719A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6548536B2 (en) | 1998-08-31 | 2003-04-15 | Kyowa Hakko Kogyo Co., Ltd. | Agent for inducing apoptosis |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6373894U (en) * | 1986-10-31 | 1988-05-17 |
-
1980
- 1980-01-31 JP JP1020980A patent/JPS56108719A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6548536B2 (en) | 1998-08-31 | 2003-04-15 | Kyowa Hakko Kogyo Co., Ltd. | Agent for inducing apoptosis |
Also Published As
Publication number | Publication date |
---|---|
JPS5734997B2 (en) | 1982-07-26 |
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