JPS56150072A - Novel quinazoline derivative and its preparation - Google Patents
Novel quinazoline derivative and its preparationInfo
- Publication number
- JPS56150072A JPS56150072A JP5275480A JP5275480A JPS56150072A JP S56150072 A JPS56150072 A JP S56150072A JP 5275480 A JP5275480 A JP 5275480A JP 5275480 A JP5275480 A JP 5275480A JP S56150072 A JPS56150072 A JP S56150072A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- quinazoline derivative
- preparation
- halogen
- integer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000002294 quinazolinyl group Chemical class N1=C(N=CC2=CC=CC=C12)* 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- JLFYGCUWEADTQJ-UHFFFAOYSA-N [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(4-methoxyphenyl)methanone Chemical compound C1=CC(OC)=CC=C1C(=O)N1CCN(C=2N=C3C=C(OC)C(OC)=CC3=C(N)N=2)CC1 JLFYGCUWEADTQJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000005530 alkylenedioxy group Chemical group 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 229940030600 antihypertensive agent Drugs 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- -1 cyclic diamine Chemical class 0.000 abstract 1
- 238000006704 dehydrohalogenation reaction Methods 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 150000003246 quinazolines Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5275480A JPS56150072A (en) | 1980-04-21 | 1980-04-21 | Novel quinazoline derivative and its preparation |
| GB8104185A GB2068961B (en) | 1980-02-13 | 1981-02-11 | Quinazoline derivatives |
| US06/233,679 US4426382A (en) | 1980-02-13 | 1981-02-11 | 4-Amino-6,7-dimethoxy-2-piperazinylquinazoline derivatives, their preparation and use |
| CH94481A CH644857A5 (de) | 1980-02-13 | 1981-02-12 | Piperazinylchinazolin- und homopiperazinylchinazolinderivate sowie verfahren zu deren herstellung und solche derivate enthaltende arzneimittel. |
| ES499377A ES8207169A1 (es) | 1980-02-13 | 1981-02-12 | Un procedimiento para la preparacion de nuevos derivados de piperazinilquinazolina y de homopiperazinilquinazolina hi- pertensora con acticidad. |
| CA000370761A CA1154765A (en) | 1980-02-13 | 1981-02-12 | 4-amino-6, 7-dimethoxy-2-piperazinylquinazoline derivatives, their preparation and use |
| NL8100726A NL191208C (nl) | 1980-02-13 | 1981-02-13 | 4-Amino-6,7-dimethoxy-2-[4-(gesubstitueerd carbonyl)-1-piperazinylchinazoline-verbindingen met hypertensie bestrijdende werkzaamheid en farmaceutische preparaten, die deze verbindingen bevatten. |
| FR8102821A FR2475548A1 (fr) | 1980-02-13 | 1981-02-13 | Nouveaux derives de quinazoline, leur procede de preparation et leur application en therapeutique |
| IT67213/81A IT1172225B (it) | 1980-02-13 | 1981-02-13 | Derivati della 4-ammino-6,7-dimetossi-2-piperazinil-chinazolina, loro preparazione ed impiego |
| DE19813105330 DE3105330A1 (de) | 1980-02-13 | 1981-02-13 | "4-amino-6,7-dimethoxy-2-piperazinylchinazolin-derivate, ihre herstellung und ihre verwendung" |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5275480A JPS56150072A (en) | 1980-04-21 | 1980-04-21 | Novel quinazoline derivative and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS56150072A true JPS56150072A (en) | 1981-11-20 |
| JPS6140229B2 JPS6140229B2 (enrdf_load_stackoverflow) | 1986-09-08 |
Family
ID=12923674
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP5275480A Granted JPS56150072A (en) | 1980-02-13 | 1980-04-21 | Novel quinazoline derivative and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS56150072A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57116052A (en) * | 1981-01-13 | 1982-07-19 | Sankyo Co Ltd | Quinazoline derivative and its preparation |
-
1980
- 1980-04-21 JP JP5275480A patent/JPS56150072A/ja active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57116052A (en) * | 1981-01-13 | 1982-07-19 | Sankyo Co Ltd | Quinazoline derivative and its preparation |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6140229B2 (enrdf_load_stackoverflow) | 1986-09-08 |
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