JPS56103180A - Novel quinazoline derivative and its preparation - Google Patents
Novel quinazoline derivative and its preparationInfo
- Publication number
- JPS56103180A JPS56103180A JP654180A JP654180A JPS56103180A JP S56103180 A JPS56103180 A JP S56103180A JP 654180 A JP654180 A JP 654180A JP 654180 A JP654180 A JP 654180A JP S56103180 A JPS56103180 A JP S56103180A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- quinazoline derivative
- preparation
- novel quinazoline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A quinazoline derivative of formula I and an acid addition salt thereof.
EXAMPLE: 2-[ 4-( 3,4-Methylenedioxybenzoyl )piperazino ]-4-amino-6,7-dimethoxyquinazoline.
USE: A hypotensive agent effective against essential hypertension, renovascular hypertension, etc. having a prolonged and powerful hypotensive effect with little inhibiting effect on the sympathetic nerve and low toxicity.
PROCESS: A compound of formula II (X is halogen or alkylthio) is reacted with a compound of formula III in an inert organic solvent at normal to higher pressure under cooling or heating to give the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP654180A JPS56103180A (en) | 1980-01-22 | 1980-01-22 | Novel quinazoline derivative and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP654180A JPS56103180A (en) | 1980-01-22 | 1980-01-22 | Novel quinazoline derivative and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS56103180A true JPS56103180A (en) | 1981-08-18 |
Family
ID=11641195
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP654180A Pending JPS56103180A (en) | 1980-01-22 | 1980-01-22 | Novel quinazoline derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56103180A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102276576A (en) * | 2011-06-02 | 2011-12-14 | 西北工业大学 | benzamide compound and preparation method thereof |
US20200222405A1 (en) * | 2017-07-06 | 2020-07-16 | Case Western Reserve University | Peptide and small molecule agonists of epha and their uses |
-
1980
- 1980-01-22 JP JP654180A patent/JPS56103180A/en active Pending
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102276576A (en) * | 2011-06-02 | 2011-12-14 | 西北工业大学 | benzamide compound and preparation method thereof |
US20200222405A1 (en) * | 2017-07-06 | 2020-07-16 | Case Western Reserve University | Peptide and small molecule agonists of epha and their uses |
US11944624B2 (en) * | 2017-07-06 | 2024-04-02 | Case Western Reserve University | Peptide and small molecule agonists of EphA and their uses |
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