JPS56147798A - Tylosin derivative - Google Patents

Info

Publication number

JPS56147798A

JPS56147798A JP4252180A JP4252180A JPS56147798A JP S56147798 A JPS56147798 A JP S56147798A JP 4252180 A JP4252180 A JP 4252180A JP 4252180 A JP4252180 A JP 4252180A JP S56147798 A JPS56147798 A JP S56147798A

Authority

JP

Japan

Prior art keywords

formula

compound shown

tylosin

demycarosyltylosin

macrolide

Prior art date

1980-03-31

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
• Discuss

• WBPYTXDJUQJLPQ-VMXQISHHSA-N tylosin Chemical class O([C@@H]1[C@@H](C)O[C@H]([C@@H]([C@H]1N(C)C)O)O[C@@H]1[C@@H](C)[C@H](O)CC(=O)O[C@@H]([C@H](/C=C(\C)/C=C/C(=O)[C@H](C)C[C@@H]1CC=O)CO[C@H]1[C@@H]([C@H](OC)[C@H](O)[C@@H](C)O1)OC)CC)[C@H]1C[C@@](C)(O)[C@@H](O)[C@H](C)O1 WBPYTXDJUQJLPQ-VMXQISHHSA-N 0.000 title abstract 3
• 150000001875 compounds Chemical class 0.000 abstract 5
• 239000003120 macrolide antibiotic agent Substances 0.000 abstract 3
• 241000894006 Bacteria Species 0.000 abstract 2
• ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 abstract 2
• 241001465754 Metazoa Species 0.000 abstract 1
• 239000004104 Oleandomycin Substances 0.000 abstract 1
• RZPAKFUAFGMUPI-UHFFFAOYSA-N Oleandomycin Natural products O1C(C)C(O)C(OC)CC1OC1C(C)C(=O)OC(C)C(C)C(O)C(C)C(=O)C2(OC2)CC(C)C(OC2C(C(CC(C)O2)N(C)C)O)C1C RZPAKFUAFGMUPI-UHFFFAOYSA-N 0.000 abstract 1
• 239000004182 Tylosin Substances 0.000 abstract 1
• 229930194936 Tylosin Natural products 0.000 abstract 1
• 230000000845 anti-microbial effect Effects 0.000 abstract 1
• 239000004599 antimicrobial Substances 0.000 abstract 1
• 230000000694 effects Effects 0.000 abstract 1
• 229960003276 erythromycin Drugs 0.000 abstract 1
• 239000002778 food additive Substances 0.000 abstract 1
• 235000013373 food additive Nutrition 0.000 abstract 1
• 239000000463 material Substances 0.000 abstract 1
• 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
• RZPAKFUAFGMUPI-KGIGTXTPSA-N oleandomycin Chemical compound O1[C@@H](C)[C@H](O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](C)C(=O)O[C@H](C)[C@H](C)[C@H](O)[C@@H](C)C(=O)[C@]2(OC2)C[C@H](C)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C RZPAKFUAFGMUPI-KGIGTXTPSA-N 0.000 abstract 1
• 229960002351 oleandomycin Drugs 0.000 abstract 1
• 235000019367 oleandomycin Nutrition 0.000 abstract 1
• 239000002798 polar solvent Substances 0.000 abstract 1
• 150000003839 salts Chemical class 0.000 abstract 1
• 239000012279 sodium borohydride Substances 0.000 abstract 1
• 229910000033 sodium borohydride Inorganic materials 0.000 abstract 1
• 235000019375 tylosin Nutrition 0.000 abstract 1
• 229960004059 tylosin Drugs 0.000 abstract 1