JPS56131581A - Benzoxazole and benzothiazole compound - Google Patents

Benzoxazole and benzothiazole compound

Info

Publication number
JPS56131581A
JPS56131581A JP2323281A JP2323281A JPS56131581A JP S56131581 A JPS56131581 A JP S56131581A JP 2323281 A JP2323281 A JP 2323281A JP 2323281 A JP2323281 A JP 2323281A JP S56131581 A JPS56131581 A JP S56131581A
Authority
JP
Japan
Prior art keywords
carbon atoms
substituted
group
general formula
hydrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2323281A
Other languages
English (en)
Other versions
JPS6334154B2 (ja
Inventor
Haueru Noruberuto
Haideru Yohahimu
Sutain Heruberuto
Ausuteru Fuorukuharuto
Raifuen Manfuretsudo
Deiederen Buiri
Haaruman Barutaa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of JPS56131581A publication Critical patent/JPS56131581A/ja
Publication of JPS6334154B2 publication Critical patent/JPS6334154B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
JP2323281A 1980-02-22 1981-02-20 Benzoxazole and benzothiazole compound Granted JPS56131581A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803006671 DE3006671A1 (de) 1980-02-22 1980-02-22 Neue benzoxazole, deren herstellung und deren verwendung als arzneumittel

Publications (2)

Publication Number Publication Date
JPS56131581A true JPS56131581A (en) 1981-10-15
JPS6334154B2 JPS6334154B2 (ja) 1988-07-08

Family

ID=6095308

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2323281A Granted JPS56131581A (en) 1980-02-22 1981-02-20 Benzoxazole and benzothiazole compound

Country Status (19)

Country Link
EP (1) EP0034743B1 (ja)
JP (1) JPS56131581A (ja)
AT (1) ATE7696T1 (ja)
AU (1) AU543524B2 (ja)
CA (1) CA1166252A (ja)
DE (2) DE3006671A1 (ja)
DK (1) DK151018C (ja)
ES (3) ES499378A0 (ja)
FI (1) FI73426C (ja)
GR (1) GR74154B (ja)
HK (1) HK50785A (ja)
IE (1) IE51012B1 (ja)
IL (1) IL62181A (ja)
NO (1) NO157895C (ja)
NZ (1) NZ196313A (ja)
PH (1) PH21232A (ja)
PT (1) PT72546B (ja)
SG (1) SG885G (ja)
ZA (1) ZA811130B (ja)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1199027A (en) * 1981-11-12 1986-01-07 Stuart D. Mills Heterocyclic derivatives of pyridazinone, thiadiazinone, oxadiazinone and triazinone
EP0809492A4 (en) 1995-02-17 2007-01-24 Smithkline Beecham Corp IL-8 RECEPTOR ANTAGONISTS
US6262113B1 (en) 1996-03-20 2001-07-17 Smithkline Beecham Corporation IL-8 receptor antagonists
US6211373B1 (en) 1996-03-20 2001-04-03 Smithkline Beecham Corporation Phenyl urea antagonists of the IL-8 receptor
US6133319A (en) * 1996-06-27 2000-10-17 Smithkline Beecham Corporation IL-8 receptor antagonists
EP0915651A4 (en) 1996-06-27 2001-10-24 Smithkline Beecham Corp IL-8 RECEPTOR ANTAGONISTS
UY32138A (es) 2008-09-25 2010-04-30 Boehringer Ingelheim Int Amidas sustituidas del ácido 2-(2,6-dicloro-fenilamino)-6-fluoro-1-metil-1h-bencimidazol-5-carboxílico y sus sales farmacéuticamente aceptables
UY32470A (es) 2009-03-05 2010-10-29 Boehringer Ingelheim Int Derivados de 2-{2-cloro-5-[(sustituido) metil]fenilamino} -1-metil]fenilamino}-1-metilbencimidazol-5-carboxamidas-n-(sustituidas) y sus sales fisiológicamente aceptables, composiciones conteniéndolos y aplicaciones
US8586604B2 (en) 2010-08-20 2013-11-19 Boehringer Ingelheim International Gmbh Inhibitors of the microsomal prostaglandin E2 synthase-1
US8759537B2 (en) 2010-08-20 2014-06-24 Boehringer Ingelheim International Gmbh 3H-imidazo [4, 5-C] pyridine-6-carboxamides as anti-inflammatory agents
US8674113B2 (en) 2010-12-10 2014-03-18 Boehringer Ingelheim International Gmbh Compounds
US8486968B2 (en) 2010-12-10 2013-07-16 Boehringer Ingelheim International Gmbh Compounds
US8466186B2 (en) 2010-12-10 2013-06-18 Boehringer Ingelheim International Gmbh Compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2516040C2 (de) * 1974-06-10 1984-12-20 Dr. Karl Thomae Gmbh, 7950 Biberach Benzimidazole, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE2436279A1 (de) * 1974-07-27 1976-02-12 Henkel & Cie Gmbh Neue benzoxazol-2-yl-substituierte imidazoline und tetrahydropyrimidine, deren herstellung sowie diese enthaltende kosmetische praeparationen

Also Published As

Publication number Publication date
PT72546B (de) 1982-10-21
ES8206519A1 (es) 1982-08-16
NZ196313A (en) 1984-07-06
FI73426B (fi) 1987-06-30
DE3006671A1 (de) 1981-08-27
ES8302699A1 (es) 1983-01-16
PH21232A (en) 1987-08-21
NO157895B (no) 1988-02-29
EP0034743A1 (de) 1981-09-02
DK151018C (da) 1988-06-20
FI73426C (fi) 1987-10-09
IL62181A (en) 1984-10-31
NO810586L (no) 1981-08-24
JPS6334154B2 (ja) 1988-07-08
DK151018B (da) 1987-10-12
PT72546A (de) 1981-03-01
IL62181A0 (en) 1981-03-31
ES8302700A1 (es) 1983-01-16
NO157895C (no) 1988-06-08
AU543524B2 (en) 1985-04-26
ES499378A0 (es) 1982-08-16
EP0034743B1 (de) 1984-05-30
AU6751981A (en) 1981-08-27
ES509533A0 (es) 1983-01-16
IE51012B1 (en) 1986-09-03
FI810535L (fi) 1981-08-23
DK73781A (da) 1981-08-23
ATE7696T1 (de) 1984-06-15
GR74154B (ja) 1984-06-06
ZA811130B (en) 1982-10-27
IE810343L (en) 1981-08-22
HK50785A (en) 1985-07-12
SG885G (en) 1985-11-15
CA1166252A (en) 1984-04-24
ES509532A0 (es) 1983-01-16
DE3163797D1 (en) 1984-07-05

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