JPS56128783A - Beta-lactam antibacterial compound, its manufacture and its medicinal compound - Google Patents
Beta-lactam antibacterial compound, its manufacture and its medicinal compoundInfo
- Publication number
- JPS56128783A JPS56128783A JP2079881A JP2079881A JPS56128783A JP S56128783 A JPS56128783 A JP S56128783A JP 2079881 A JP2079881 A JP 2079881A JP 2079881 A JP2079881 A JP 2079881A JP S56128783 A JPS56128783 A JP S56128783A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- beta
- manufacture
- medicinal
- lactam antibacterial
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title 1
- 229940124586 β-lactam antibiotics Drugs 0.000 title 1
- 150000002148 esters Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 125000000852 azido group Chemical group *N=[N+]=[N-] 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/24—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/568—Four-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8005037 | 1980-02-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS56128783A true JPS56128783A (en) | 1981-10-08 |
Family
ID=10511363
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2079881A Pending JPS56128783A (en) | 1980-02-14 | 1981-02-14 | Beta-lactam antibacterial compound, its manufacture and its medicinal compound |
Country Status (5)
Country | Link |
---|---|
US (1) | US4407815A (ja) |
EP (1) | EP0034443B1 (ja) |
JP (1) | JPS56128783A (ja) |
AT (1) | ATE9584T1 (ja) |
DE (1) | DE3166235D1 (ja) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0073100B1 (en) * | 1981-08-13 | 1985-10-02 | Beecham Group Plc | Beta-lactam compounds, their preparation and their use |
JPS59106489A (ja) * | 1982-12-10 | 1984-06-20 | Sanraku Inc | 新規β−ラクタム誘導体及びその製造方法 |
US4885362A (en) * | 1988-06-06 | 1989-12-05 | Eli Lilly And Company | Azetidinone intermediates for 1-carba(dethia)caphalosporins |
US5138050A (en) * | 1988-06-30 | 1992-08-11 | Merck & Co., Inc. | 6-amido-1-methyl carbapenems |
US5395931A (en) * | 1988-06-30 | 1995-03-07 | Merck & Co., Inc. | 6-amido-1-methyl-2-(substituted-thio)carbapenems |
US5055463A (en) * | 1989-02-02 | 1991-10-08 | Merck & Co., Inc. | Spirocyclic 6-amido carbapenems |
WO2019089498A1 (en) * | 2017-10-30 | 2019-05-09 | Theracaine Llc | Hydrophobic ammonium and phosphonium salts |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4052408A (en) * | 1968-07-23 | 1977-10-04 | Ciba-Geigy Corporation | Oxyacetic acid compounds and process for their manufacture |
US3951951A (en) * | 1974-10-11 | 1976-04-20 | Beecham Group Limited | Azetidinones |
US4144333A (en) * | 1976-11-15 | 1979-03-13 | Smithkline Corporation | Monocyclic beta-lactams with antibacterial activity |
-
1981
- 1981-02-04 EP EP81300479A patent/EP0034443B1/en not_active Expired
- 1981-02-04 AT AT81300479T patent/ATE9584T1/de not_active IP Right Cessation
- 1981-02-04 DE DE8181300479T patent/DE3166235D1/de not_active Expired
- 1981-02-10 US US06/233,180 patent/US4407815A/en not_active Expired - Fee Related
- 1981-02-14 JP JP2079881A patent/JPS56128783A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0034443A3 (en) | 1981-10-07 |
ATE9584T1 (de) | 1984-10-15 |
EP0034443A2 (en) | 1981-08-26 |
US4407815A (en) | 1983-10-04 |
DE3166235D1 (en) | 1984-10-31 |
EP0034443B1 (en) | 1984-09-26 |
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