ES8306152A1 - Un procedimiento para la preparacion de nuevos derivados de 7-oxo-1-azabiciclo (3.2.0) hepteno. - Google Patents
Un procedimiento para la preparacion de nuevos derivados de 7-oxo-1-azabiciclo (3.2.0) hepteno.Info
- Publication number
- ES8306152A1 ES8306152A1 ES514807A ES514807A ES8306152A1 ES 8306152 A1 ES8306152 A1 ES 8306152A1 ES 514807 A ES514807 A ES 514807A ES 514807 A ES514807 A ES 514807A ES 8306152 A1 ES8306152 A1 ES 8306152A1
- Authority
- ES
- Spain
- Prior art keywords
- beta
- lactam antibiotics
- chem
- amine
- processes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE 7-OXO-1-AZABICICLO 3.2.0 HEPTENO Y DE SUS SALES Y ESTERES HIDROLIZABLES ~AIN VIVO~B FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE X ES ALCANODIILO C <- ; Y R , R Y R PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II), O UN DERIVADO PROTEGIDO DEL MISMO, CON UN COMPUESTO DE FORMULA (III) O (IV), EN LAS QUE R ES ALQUILO C <- ; T ES OXIGENO O AZUFRE; Y ES HALOGENO O ALCOXI C <- ; Y Z ES UN ION SALIFICANTE. LA REACCION SE LLEVA A CABO EN DISOLUCION ACUOSA O ACUO-ORGANICA, A UNA TEMPERATURA COMPRENDIDA ENTRE 0 C Y LA AMBIENTE. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE AFECCIONES BACTERIANAS.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8124312 | 1981-08-08 | ||
| GB8133768 | 1981-11-09 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8306152A1 true ES8306152A1 (es) | 1983-05-01 |
| ES514807A0 ES514807A0 (es) | 1983-05-01 |
Family
ID=26280399
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES514807A Granted ES514807A0 (es) | 1981-08-08 | 1982-08-06 | Un procedimiento para la preparacion de nuevos derivados de 7-oxo-1-azabiciclo (3.2.0) hepteno. |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP0072121A1 (es) |
| AU (1) | AU8693782A (es) |
| ES (1) | ES514807A0 (es) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3070269D1 (en) * | 1979-08-10 | 1985-04-18 | Beecham Group Plc | Beta-lactam antibiotics, their preparation, pharmaceutical compositions containing them and their preparation |
| EP0033209B1 (en) * | 1980-01-25 | 1984-06-13 | Beecham Group Plc | Beta-lactam containing compounds, their preparation and use |
-
1982
- 1982-07-22 EP EP82303859A patent/EP0072121A1/en not_active Withdrawn
- 1982-08-06 AU AU86937/82A patent/AU8693782A/en not_active Abandoned
- 1982-08-06 ES ES514807A patent/ES514807A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| EP0072121A1 (en) | 1983-02-16 |
| AU8693782A (en) | 1983-02-17 |
| ES514807A0 (es) | 1983-05-01 |
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