JPS56125392A - Cepham and cephem compound and preparation thereof - Google Patents
Cepham and cephem compound and preparation thereofInfo
- Publication number
- JPS56125392A JPS56125392A JP2967680A JP2967680A JPS56125392A JP S56125392 A JPS56125392 A JP S56125392A JP 2967680 A JP2967680 A JP 2967680A JP 2967680 A JP2967680 A JP 2967680A JP S56125392 A JPS56125392 A JP S56125392A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- salt
- cepham
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2967680A JPS56125392A (en) | 1980-03-06 | 1980-03-06 | Cepham and cephem compound and preparation thereof |
EP81101456A EP0036510B1 (en) | 1980-03-06 | 1981-02-28 | Synisomer cephalosporin compounds and processes for their preparation |
AT81101456T ATE10372T1 (de) | 1980-03-06 | 1981-02-28 | Synisomer von cephalosporinverbindungen und verfahren zu ihrer herstellung. |
EP83106851A EP0096903A3 (en) | 1980-03-06 | 1981-02-28 | Intermediate compounds for preparing cephem compounds and processes for their preparation |
DE8181101456T DE3167258D1 (en) | 1980-03-06 | 1981-02-28 | Synisomer cephalosporin compounds and processes for their preparation |
US06/240,469 US4368325A (en) | 1980-03-06 | 1981-03-04 | Processes for preparing 3-cephem compounds |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2967680A JPS56125392A (en) | 1980-03-06 | 1980-03-06 | Cepham and cephem compound and preparation thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56125392A true JPS56125392A (en) | 1981-10-01 |
JPH0246593B2 JPH0246593B2 (ja) | 1990-10-16 |
Family
ID=12282708
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2967680A Granted JPS56125392A (en) | 1980-03-06 | 1980-03-06 | Cepham and cephem compound and preparation thereof |
Country Status (5)
Country | Link |
---|---|
US (1) | US4368325A (ja) |
EP (2) | EP0036510B1 (ja) |
JP (1) | JPS56125392A (ja) |
AT (1) | ATE10372T1 (ja) |
DE (1) | DE3167258D1 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61171464A (ja) * | 1985-01-23 | 1986-08-02 | Dai Ichi Seiyaku Co Ltd | オキシイミノ酪酸誘導体の製法 |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PH17188A (en) * | 1977-03-14 | 1984-06-14 | Fujisawa Pharmaceutical Co | New cephem and cepham compounds and their pharmaceutical compositions and method of use |
JPS57193489A (en) * | 1981-05-21 | 1982-11-27 | Fujisawa Pharmaceut Co Ltd | Syn-isomer of 7-substituted-3-cephem-4-carboxylic acid ester and its preparation |
DE3528753A1 (de) * | 1985-08-10 | 1987-02-19 | Bayer Ag | Substituierte pyrazolin-5-one |
US5604222A (en) * | 1993-12-27 | 1997-02-18 | Lupin Laboratories, Ltd. | Method for the preparation of 2-chloro sulfinyl azetidinones |
US5578721A (en) * | 1994-07-11 | 1996-11-26 | Lupin Laboratories Limited | Process for preparation of 3-exomethylene cepham sulfoxide esters |
CN102070560A (zh) * | 2010-12-10 | 2011-05-25 | 湖北楚阳科技股份有限公司 | 利用相转移技术生产氨噻肟酸的制备方法 |
US20130065874A1 (en) | 2011-09-09 | 2013-03-14 | Cubist Pharmaceuticals, Inc. | Methods for treating intrapulmonary infections |
US8809314B1 (en) | 2012-09-07 | 2014-08-19 | Cubist Pharmacueticals, Inc. | Cephalosporin compound |
US8476425B1 (en) | 2012-09-27 | 2013-07-02 | Cubist Pharmaceuticals, Inc. | Tazobactam arginine compositions |
US9872906B2 (en) | 2013-03-15 | 2018-01-23 | Merck Sharp & Dohme Corp. | Ceftolozane antibiotic compositions |
KR102226197B1 (ko) | 2013-03-15 | 2021-03-11 | 머크 샤프 앤드 돔 코포레이션 | 세프톨로잔 항균성 조성물 |
US20140274991A1 (en) | 2013-03-15 | 2014-09-18 | Cubist Pharmaceuticals, Inc. | Ceftolozane pharmaceutical compositions |
AU2014233637A1 (en) | 2013-09-09 | 2015-03-26 | Merck Sharp & Dohme Corp. | Treating infections with ceftolozane/tazobactam in subjects having impaired renal function |
US20150094293A1 (en) | 2013-09-27 | 2015-04-02 | Calixa Therapeutics, Inc. | Solid forms of ceftolozane |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1536281A (en) * | 1975-06-09 | 1978-12-20 | Takeda Chemical Industries Ltd | Cephem compounds |
JPS6011713B2 (ja) * | 1976-09-08 | 1985-03-27 | 武田薬品工業株式会社 | セフアロスポリン誘導体およびその製造法 |
JPS5498795A (en) * | 1978-01-13 | 1979-08-03 | Takeda Chem Ind Ltd | Cephalosporin derivative and its preparation |
EP0048504B1 (en) * | 1978-09-12 | 1988-08-17 | Fujisawa Pharmaceutical Co., Ltd. | Intermediate compounds for preparing cephem compounds; processes for their preparation and processes for preparing cephem compounds |
-
1980
- 1980-03-06 JP JP2967680A patent/JPS56125392A/ja active Granted
-
1981
- 1981-02-28 EP EP81101456A patent/EP0036510B1/en not_active Expired
- 1981-02-28 AT AT81101456T patent/ATE10372T1/de not_active IP Right Cessation
- 1981-02-28 EP EP83106851A patent/EP0096903A3/en not_active Withdrawn
- 1981-02-28 DE DE8181101456T patent/DE3167258D1/de not_active Expired
- 1981-03-04 US US06/240,469 patent/US4368325A/en not_active Expired - Lifetime
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61171464A (ja) * | 1985-01-23 | 1986-08-02 | Dai Ichi Seiyaku Co Ltd | オキシイミノ酪酸誘導体の製法 |
Also Published As
Publication number | Publication date |
---|---|
EP0036510B1 (en) | 1984-11-21 |
ATE10372T1 (de) | 1984-12-15 |
JPH0246593B2 (ja) | 1990-10-16 |
EP0096903A3 (en) | 1984-02-01 |
US4368325A (en) | 1983-01-11 |
DE3167258D1 (en) | 1985-01-03 |
EP0096903A2 (en) | 1983-12-28 |
EP0036510A2 (en) | 1981-09-30 |
EP0036510A3 (en) | 1981-12-02 |
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