JPS5724389A - Novel cephem compound, its preparation, and preventive and remedy for bacteriosis - Google Patents

Novel cephem compound, its preparation, and preventive and remedy for bacteriosis

Info

Publication number
JPS5724389A
JPS5724389A JP8939181A JP8939181A JPS5724389A JP S5724389 A JPS5724389 A JP S5724389A JP 8939181 A JP8939181 A JP 8939181A JP 8939181 A JP8939181 A JP 8939181A JP S5724389 A JPS5724389 A JP S5724389A
Authority
JP
Japan
Prior art keywords
compound
substituted
formula
bacteriosis
remedy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP8939181A
Other languages
Japanese (ja)
Other versions
JPH031314B2 (en
Inventor
Tsutomu Terachi
Kazuo Sakane
Jiro Goto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/160,904 external-priority patent/US4381299A/en
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of JPS5724389A publication Critical patent/JPS5724389A/en
Publication of JPH031314B2 publication Critical patent/JPH031314B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:The compound of formula I [R1 is amino or protected amino; R2 is H, lower aliphatic hydrocarbon group, cyclo(lower)alkyl, etc.; R3 is thiazolio or pyridynio which may be substituted with halogen, etc.] and its salt.
EXAMPLE: 7-[ 2-Ethoxyimino-2-(5-amino-1,2,4-thiadiazol-3-yl)acetamido ]-3-(3- thiazoliomethyl)-3-cephem-4-carboxylate (syn-isomer).
USE: Preventive and remedy for bacteriosis.
PROCESS: The compound of formula I is prepared by reacting the compound of formula II (R4 is a group which can be substituted with R3) or its salt with the compound of formula III (R3a is thiazol which may be substituted with proper substituent group or pyridine which is substituted with halogen, etc.) in a solvent such as a phosphate buffer solution, pref. a solvent having strong polarity, if necessary in the presence of a base at room temperature under mild heating or heating.
COPYRIGHT: (C)1982,JPO&Japio
JP8939181A 1980-06-18 1981-06-09 Novel cephem compound, its preparation, and preventive and remedy for bacteriosis Granted JPS5724389A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/160,904 US4381299A (en) 1980-03-07 1980-06-18 7-Amino-thiadiazole oxyimino derivatives of cephem and cepham compounds

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP63139782A Division JPH01151588A (en) 1980-06-18 1988-06-06 Novel cephem compound and production thereof

Publications (2)

Publication Number Publication Date
JPS5724389A true JPS5724389A (en) 1982-02-08
JPH031314B2 JPH031314B2 (en) 1991-01-10

Family

ID=22578970

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8939181A Granted JPS5724389A (en) 1980-06-18 1981-06-09 Novel cephem compound, its preparation, and preventive and remedy for bacteriosis

Country Status (4)

Country Link
JP (1) JPS5724389A (en)
AU (1) AU7144281A (en)
ES (1) ES8207548A1 (en)
ZA (1) ZA813787B (en)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5841887A (en) * 1981-08-19 1983-03-11 Fujisawa Pharmaceut Co Ltd Novel cephem compound, its preparation and preventive or remedy for microbism
JPS5859992A (en) * 1981-09-14 1983-04-09 Fujisawa Pharmaceut Co Ltd Novel cephen compound, its preparation and preventing agent and remedy for microbism
JPS58162592A (en) * 1982-03-04 1983-09-27 ヘキスト　アクチェンゲゼルシャフト Cephalosporin derivative and manufacture
JPS6067483A (en) * 1983-09-24 1985-04-17 Sankyo Co Ltd Cephalosporin derivative containing thiazoliomethyl- substituted group
JPS60226884A (en) * 1984-04-25 1985-11-12 Dai Ichi Seiyaku Co Ltd Cephalosporin derivative
JPS6122089A (en) * 1984-07-06 1986-01-30 Fujisawa Pharmaceut Co Ltd Cephem compound
JPS61178994A (en) * 1984-06-08 1986-08-11 Takeda Chem Ind Ltd Cephem compound
JPS62119275A (en) * 1985-11-19 1987-05-30 Nippon Oil & Fats Co Ltd Intercoating material composition for automobile
JPS62151470A (en) * 1985-12-26 1987-07-06 Dainippon Ink & Chem Inc Resin composition for stoving paint
JPH02117679A (en) * 1989-09-22 1990-05-02 Sankyo Co Ltd Cephalosporin derivative containing thiazoliomethyl-substituted group
JPH0539292A (en) * 1983-10-31 1993-02-19 Fujisawa Pharmaceut Co Ltd New cephem compound

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5328141A (en) * 1971-05-14 1978-03-16 Glaxo Lab Ltd Production of novel carboxylic acid
JPS55105689A (en) * 1978-12-29 1980-08-13 Fujisawa Pharmaceut Co Ltd Novel cephem and cepham compounds, their preparation and preventive and remedy for microbism
JPS57112396A (en) * 1979-10-12 1982-07-13 Fujisawa Pharmaceut Co Ltd Novel cephem compound, its preparation and prophylactic or remedy for microbism

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5328141A (en) * 1971-05-14 1978-03-16 Glaxo Lab Ltd Production of novel carboxylic acid
JPS55105689A (en) * 1978-12-29 1980-08-13 Fujisawa Pharmaceut Co Ltd Novel cephem and cepham compounds, their preparation and preventive and remedy for microbism
JPS57112396A (en) * 1979-10-12 1982-07-13 Fujisawa Pharmaceut Co Ltd Novel cephem compound, its preparation and prophylactic or remedy for microbism

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5841887A (en) * 1981-08-19 1983-03-11 Fujisawa Pharmaceut Co Ltd Novel cephem compound, its preparation and preventive or remedy for microbism
JPH0453868B2 (en) * 1981-08-19 1992-08-27 Fujisawa Pharmaceutical Co
JPS5859992A (en) * 1981-09-14 1983-04-09 Fujisawa Pharmaceut Co Ltd Novel cephen compound, its preparation and preventing agent and remedy for microbism
JPH0526795B2 (en) * 1981-09-14 1993-04-19 Fujisawa Pharmaceutical Co
JPS58162592A (en) * 1982-03-04 1983-09-27 ヘキスト　アクチェンゲゼルシャフト Cephalosporin derivative and manufacture
JPH0324477B2 (en) * 1983-09-24 1991-04-03 Sankyo Co
JPS6067483A (en) * 1983-09-24 1985-04-17 Sankyo Co Ltd Cephalosporin derivative containing thiazoliomethyl- substituted group
JPH0539292A (en) * 1983-10-31 1993-02-19 Fujisawa Pharmaceut Co Ltd New cephem compound
JPS60226884A (en) * 1984-04-25 1985-11-12 Dai Ichi Seiyaku Co Ltd Cephalosporin derivative
JPS61178994A (en) * 1984-06-08 1986-08-11 Takeda Chem Ind Ltd Cephem compound
JPS6122089A (en) * 1984-07-06 1986-01-30 Fujisawa Pharmaceut Co Ltd Cephem compound
JPS62119275A (en) * 1985-11-19 1987-05-30 Nippon Oil & Fats Co Ltd Intercoating material composition for automobile
JPS62151470A (en) * 1985-12-26 1987-07-06 Dainippon Ink & Chem Inc Resin composition for stoving paint
JPH02117679A (en) * 1989-09-22 1990-05-02 Sankyo Co Ltd Cephalosporin derivative containing thiazoliomethyl-substituted group

Also Published As

Publication number Publication date
ES505498A0 (en) 1982-09-16
JPH031314B2 (en) 1991-01-10
ZA813787B (en) 1982-07-28
AU7144281A (en) 1981-12-24
ES8207548A1 (en) 1982-09-16

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