JPS56118085A - 2-methylcephalosporin derivative and its preparation - Google Patents

2-methylcephalosporin derivative and its preparation

Info

Publication number
JPS56118085A
JPS56118085A JP2295180A JP2295180A JPS56118085A JP S56118085 A JPS56118085 A JP S56118085A JP 2295180 A JP2295180 A JP 2295180A JP 2295180 A JP2295180 A JP 2295180A JP S56118085 A JPS56118085 A JP S56118085A
Authority
JP
Japan
Prior art keywords
compound
formula
derivative
react
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2295180A
Other languages
English (en)
Other versions
JPH0160477B2 (ja
Inventor
Satoshi Horii
Nariaki Mizogami
Yutaka Kuwata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to JP2295180A priority Critical patent/JPS56118085A/ja
Priority to US06/235,998 priority patent/US4463172A/en
Priority to CA000371344A priority patent/CA1176628A/en
Priority to EP81300765A priority patent/EP0035357A1/en
Publication of JPS56118085A publication Critical patent/JPS56118085A/ja
Publication of JPH0160477B2 publication Critical patent/JPH0160477B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02Preparation
    • C07D501/04Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2295180A 1980-02-25 1980-02-25 2-methylcephalosporin derivative and its preparation Granted JPS56118085A (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2295180A JPS56118085A (en) 1980-02-25 1980-02-25 2-methylcephalosporin derivative and its preparation
US06/235,998 US4463172A (en) 1980-02-25 1981-02-19 Process for producing 2-methyl cephem-2-em and 2-methylcephem-3-em derivitaves
CA000371344A CA1176628A (en) 1980-02-25 1981-02-20 2-methylcephalosporins and production thereof
EP81300765A EP0035357A1 (en) 1980-02-25 1981-02-24 2-Methylcephalosporins and production thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2295180A JPS56118085A (en) 1980-02-25 1980-02-25 2-methylcephalosporin derivative and its preparation

Publications (2)

Publication Number Publication Date
JPS56118085A true JPS56118085A (en) 1981-09-16
JPH0160477B2 JPH0160477B2 (ja) 1989-12-22

Family

ID=12096914

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2295180A Granted JPS56118085A (en) 1980-02-25 1980-02-25 2-methylcephalosporin derivative and its preparation

Country Status (4)

Country Link
US (1) US4463172A (ja)
EP (1) EP0035357A1 (ja)
JP (1) JPS56118085A (ja)
CA (1) CA1176628A (ja)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5951291A (ja) * 1982-09-16 1984-03-24 Meiji Seika Kaisha Ltd オキサデチアセフアロスポリン中間体およびその製造法
JPS6140291A (ja) * 1984-07-31 1986-02-26 Shionogi & Co Ltd ヒドロキシアルキルチオセフアロスポリン
WO2014069649A1 (en) * 2012-10-29 2014-05-08 Shionogi & Co., Ltd. Processes for production of intermediates for 2-alkyl cephem compounds
JP2015534995A (ja) * 2012-10-29 2015-12-07 グラクソ グループ リミテッドGlaxo Group Limited 2−置換セフェム化合物

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH21016A (en) * 1982-07-23 1987-06-30 Meiji Seika Kaisha 2-alkyl-1-oxa-dethia-cephalosporin derivatives and process for producing said compound
DK607188A (da) * 1987-11-02 1989-06-22 Merck & Co Inc Tablet indeholdende en phthalazineddikesyreforbindelse
ATE208374T1 (de) * 1992-02-18 2001-11-15 Otsuka Kagaku Kk Beta-laktam und cepham verbindungen und ihre herstellung
EP1221446B1 (en) * 1995-05-11 2005-04-06 Sandoz Ag Antibacterial cephalosporins
US20050059820A1 (en) * 2003-09-17 2005-03-17 Debashish Datta Method for manufacture of ceftriaxone sodium
US20050059821A1 (en) * 2003-09-17 2005-03-17 Debashish Datta Method for manufacture of ceftriaxone sodium
CN117586690B (zh) * 2024-01-19 2024-03-19 潍坊市兴源防水材料股份有限公司 一种双组份喷涂聚脲防水涂料

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4961194A (ja) * 1972-06-19 1974-06-13

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3647786A (en) * 1968-10-03 1972-03-07 Lilly Co Eli Preparation of cephalosporin sulfoxides
US3660396A (en) * 1970-03-04 1972-05-02 Lilly Co Eli Cephalosporin intermediates and process therefor
US3819621A (en) * 1970-12-30 1974-06-25 Fujisawa Pharmaceutical Co 3-substituted-thiomethyl-3-cephem-4-carboxylic acid derivatives
GB1565941A (en) * 1977-02-08 1980-04-23 Toyama Chemical Co Ltd Process for producing 7-(substituted)amino-3-substituted thiomethyl cephem carboxylic acids
US4144391A (en) * 1977-03-07 1979-03-13 Eli Lilly And Company Cephalosporin displacement reaction
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
GB2025933B (en) * 1978-06-13 1982-10-27 Fujisawa Pharmaceutical Co Cephem and cepham compounds

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4961194A (ja) * 1972-06-19 1974-06-13

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5951291A (ja) * 1982-09-16 1984-03-24 Meiji Seika Kaisha Ltd オキサデチアセフアロスポリン中間体およびその製造法
JPH0354672B2 (ja) * 1982-09-16 1991-08-20
JPS6140291A (ja) * 1984-07-31 1986-02-26 Shionogi & Co Ltd ヒドロキシアルキルチオセフアロスポリン
WO2014069649A1 (en) * 2012-10-29 2014-05-08 Shionogi & Co., Ltd. Processes for production of intermediates for 2-alkyl cephem compounds
JP2015534995A (ja) * 2012-10-29 2015-12-07 グラクソ グループ リミテッドGlaxo Group Limited 2−置換セフェム化合物
JP2015535210A (ja) * 2012-10-29 2015-12-10 塩野義製薬株式会社 2−アルキルセフェム化合物のための中間体の製造法

Also Published As

Publication number Publication date
JPH0160477B2 (ja) 1989-12-22
CA1176628A (en) 1984-10-23
US4463172A (en) 1984-07-31
EP0035357A1 (en) 1981-09-09

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