JPS56118048A - Phenoxyalkane derivative and its preparation - Google Patents
Phenoxyalkane derivative and its preparationInfo
- Publication number
- JPS56118048A JPS56118048A JP2192880A JP2192880A JPS56118048A JP S56118048 A JPS56118048 A JP S56118048A JP 2192880 A JP2192880 A JP 2192880A JP 2192880 A JP2192880 A JP 2192880A JP S56118048 A JPS56118048 A JP S56118048A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound shown
- intracranial pressure
- phenoxyalkane
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
NEW MATERIAL:The titled compound shown by the formula I [R1 is alkyl; R2 is alkylamino, a group shown by the formula II (R3 is H or OH; R4 is phenyl, halogeneophenyl); n is integer of 2W4] and its acid addition salt.
EXAMPLE: 1-( 4-Acetamido-2-methoxyphenoxy )-3-( isopropylamino )propane.
USE: A sthenic remedy for intracranial pressure, transquillizer, analgesic, antiemetic. Having intracranial pressure lowering action, and center inhibiting action.
PROCESS: A compound shown by the formula III (Y is reactive group or atom) is reacted with a compound shown by the formula H-R2 in a solvent, e.g., methanol, DMF, etc. at 20W100°C, to give a compound shown by the formula I. The reaction is carried out in the presence or absence of a dioxidizer (e.g., triethylamine, potassium carbonate, etc.).
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2192880A JPS56118048A (en) | 1980-02-22 | 1980-02-22 | Phenoxyalkane derivative and its preparation |
DE8181100929T DE3160397D1 (en) | 1980-02-22 | 1981-02-10 | Phenoxyalkane derivative and processes for preparing same |
EP81100929A EP0034752B1 (en) | 1980-02-22 | 1981-02-10 | Phenoxyalkane derivative and processes for preparing same |
IT19901/81A IT1167707B (en) | 1980-02-22 | 1981-02-20 | PHENOXYLANE DERIVATIVES AND RELATED PREPARATION PROCEDURES |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2192880A JPS56118048A (en) | 1980-02-22 | 1980-02-22 | Phenoxyalkane derivative and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS56118048A true JPS56118048A (en) | 1981-09-16 |
Family
ID=12068719
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2192880A Pending JPS56118048A (en) | 1980-02-22 | 1980-02-22 | Phenoxyalkane derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56118048A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0282127A2 (en) * | 1987-03-09 | 1988-09-14 | The Procter & Gamble Company | Beta-aminoethyl-substituted phenyl compounds, and anti-inflammatory or analgesic compositions containing them |
-
1980
- 1980-02-22 JP JP2192880A patent/JPS56118048A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0282127A2 (en) * | 1987-03-09 | 1988-09-14 | The Procter & Gamble Company | Beta-aminoethyl-substituted phenyl compounds, and anti-inflammatory or analgesic compositions containing them |
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