JPS5610175A - Preparation of imidazole derivative - Google Patents
Preparation of imidazole derivativeInfo
- Publication number
- JPS5610175A JPS5610175A JP8624979A JP8624979A JPS5610175A JP S5610175 A JPS5610175 A JP S5610175A JP 8624979 A JP8624979 A JP 8624979A JP 8624979 A JP8624979 A JP 8624979A JP S5610175 A JPS5610175 A JP S5610175A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- reacting
- alkyl
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000002460 imidazoles Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- XZMCDFZZKTWFGF-UHFFFAOYSA-N Cyanamide Chemical compound NC#N XZMCDFZZKTWFGF-UHFFFAOYSA-N 0.000 abstract 1
- 150000003973 alkyl amines Chemical class 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000006615 aromatic heterocyclic group Chemical group 0.000 abstract 1
- OKYPCZYFNCUUDL-UHFFFAOYSA-N n'-cyanocarbamimidoyl chloride Chemical compound ClC(=N)NC#N OKYPCZYFNCUUDL-UHFFFAOYSA-N 0.000 abstract 1
- PXQLVRUNWNTZOS-UHFFFAOYSA-N sulfanyl Chemical group [SH] PXQLVRUNWNTZOS-UHFFFAOYSA-N 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8624979A JPS5610175A (en) | 1979-07-06 | 1979-07-06 | Preparation of imidazole derivative |
PCT/JP1980/000155 WO1981000109A1 (en) | 1979-07-06 | 1980-07-04 | Process for preparing imidazole derivatives |
EP82111791A EP0081859A3 (en) | 1979-07-06 | 1980-07-04 | Process for preparing cimetidine |
EP82111790A EP0080739A3 (en) | 1979-07-06 | 1980-07-04 | Process for preparing cimetidine |
DE8080901220T DE3066829D1 (en) | 1979-07-06 | 1980-07-04 | Process for preparing imidazole derivatives |
EP80901220A EP0031388B1 (en) | 1979-07-06 | 1981-01-26 | Process for preparing imidazole derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8624979A JPS5610175A (en) | 1979-07-06 | 1979-07-06 | Preparation of imidazole derivative |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1114019A Division JPH0285261A (ja) | 1989-05-01 | 1989-05-01 | イミダゾール誘導体の製造法 |
JP1114018A Division JPH0285260A (ja) | 1989-05-01 | 1989-05-01 | イミダゾール誘導体の製造法 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5610175A true JPS5610175A (en) | 1981-02-02 |
JPH0260667B2 JPH0260667B2 (ja) | 1990-12-17 |
Family
ID=13881536
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP8624979A Granted JPS5610175A (en) | 1979-07-06 | 1979-07-06 | Preparation of imidazole derivative |
Country Status (4)
Country | Link |
---|---|
EP (3) | EP0081859A3 (ja) |
JP (1) | JPS5610175A (ja) |
DE (1) | DE3066829D1 (ja) |
WO (1) | WO1981000109A1 (ja) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU185298B (en) * | 1981-06-26 | 1984-12-28 | Richter Gedeon Vegyeszet | Process for producing cimetidine |
HU185636B (en) * | 1981-06-26 | 1985-03-28 | Richter Gedeon Vegyeszet | Process for preparing new cimetidine-hydrate /cimetidine-h/ |
EP0224612A1 (de) * | 1985-12-05 | 1987-06-10 | HEUMANN PHARMA GMBH & CO | Verfahren zur Herstellung von N-Cyano-N'-methyl-N"[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]guanidin |
US4807619A (en) * | 1986-04-07 | 1989-02-28 | Minnesota Mining And Manufacturing Company | Resilient shape-retaining fibrous filtration face mask |
JPH064601B2 (ja) * | 1987-11-04 | 1994-01-19 | 三井石油化学工業株式会社 | N−シアノ−n’−メチル−n’’−[2−{(5−メチル−1h−イミダゾール−4−イル)メチルチオ}エチルグアニジンの精製法 |
US5808090A (en) * | 1996-02-22 | 1998-09-15 | Endo Pharmaceuticals Inc. | Process for preventing precipitation in cimetidine injection solutions |
US20230349922A1 (en) | 2020-08-11 | 2023-11-02 | Université De Strasbourg | H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS53103469A (en) * | 1977-02-18 | 1978-09-08 | Yamanouchi Pharmaceut Co Ltd | Guanidine derivatives and process for their preparation |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1338169A (en) * | 1971-03-09 | 1973-11-21 | Smith Kline French Lab | Ureas thioureas and guanidines |
GB1398426A (en) * | 1972-09-05 | 1975-06-18 | Smith Kline French Lab | Heterocyclic substituted guanidines |
GB1431589A (en) * | 1973-07-13 | 1976-04-07 | Smith Kline French Lab | Ureas, thioureas and guanidines n,n-disubstituted by heterocyclo- alkylene and/or heterocycloalkylenethioalkylene groups |
GB1565966A (en) * | 1976-08-04 | 1980-04-23 | Allen & Hanburys Ltd | Aminoalkyl furan derivatives |
-
1979
- 1979-07-06 JP JP8624979A patent/JPS5610175A/ja active Granted
-
1980
- 1980-07-04 WO PCT/JP1980/000155 patent/WO1981000109A1/ja active IP Right Grant
- 1980-07-04 EP EP82111791A patent/EP0081859A3/en not_active Ceased
- 1980-07-04 DE DE8080901220T patent/DE3066829D1/de not_active Expired
- 1980-07-04 EP EP82111790A patent/EP0080739A3/en not_active Ceased
-
1981
- 1981-01-26 EP EP80901220A patent/EP0031388B1/en not_active Expired
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS53103469A (en) * | 1977-02-18 | 1978-09-08 | Yamanouchi Pharmaceut Co Ltd | Guanidine derivatives and process for their preparation |
Also Published As
Publication number | Publication date |
---|---|
EP0081859A2 (en) | 1983-06-22 |
DE3066829D1 (en) | 1984-04-12 |
EP0031388A1 (en) | 1981-07-08 |
EP0081859A3 (en) | 1983-08-17 |
WO1981000109A1 (en) | 1981-01-22 |
JPH0260667B2 (ja) | 1990-12-17 |
EP0080739A3 (en) | 1983-08-24 |
EP0080739A2 (en) | 1983-06-08 |
EP0031388B1 (en) | 1984-03-07 |
EP0031388A4 (en) | 1981-11-24 |
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