JPS5592687A - Purification of urokinase - Google Patents
Purification of urokinaseInfo
- Publication number
- JPS5592687A JPS5592687A JP16579878A JP16579878A JPS5592687A JP S5592687 A JPS5592687 A JP S5592687A JP 16579878 A JP16579878 A JP 16579878A JP 16579878 A JP16579878 A JP 16579878A JP S5592687 A JPS5592687 A JP S5592687A
- Authority
- JP
- Japan
- Prior art keywords
- urokinase
- polysaccharide
- adsorbed
- granular
- treated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000003990 Urokinase-type plasminogen activator Human genes 0.000 title abstract 7
- 108090000435 Urokinase-type plasminogen activator Proteins 0.000 title abstract 7
- 229960005356 urokinase Drugs 0.000 title abstract 7
- 238000000746 purification Methods 0.000 title 1
- 150000004676 glycans Chemical class 0.000 abstract 3
- 229920001282 polysaccharide Polymers 0.000 abstract 3
- 239000005017 polysaccharide Substances 0.000 abstract 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- 238000001042 affinity chromatography Methods 0.000 abstract 2
- 238000005342 ion exchange Methods 0.000 abstract 2
- 229920002134 Carboxymethyl cellulose Polymers 0.000 abstract 1
- 102100039419 Plasminogen activator inhibitor 2 Human genes 0.000 abstract 1
- 229920005654 Sephadex Polymers 0.000 abstract 1
- 239000012507 Sephadex™ Substances 0.000 abstract 1
- MZVQCMJNVPIDEA-UHFFFAOYSA-N [CH2]CN(CC)CC Chemical group [CH2]CN(CC)CC MZVQCMJNVPIDEA-UHFFFAOYSA-N 0.000 abstract 1
- 239000008351 acetate buffer Substances 0.000 abstract 1
- 239000007853 buffer solution Substances 0.000 abstract 1
- 239000001768 carboxy methyl cellulose Substances 0.000 abstract 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 abstract 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000002797 plasminogen activator inhibitor Substances 0.000 abstract 1
- 239000002510 pyrogen Substances 0.000 abstract 1
- 239000012266 salt solution Substances 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 108010065822 urokinase inhibitor Proteins 0.000 abstract 1
Landscapes
- Enzymes And Modification Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16579878A JPS5592687A (en) | 1978-12-28 | 1978-12-28 | Purification of urokinase |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16579878A JPS5592687A (en) | 1978-12-28 | 1978-12-28 | Purification of urokinase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5592687A true JPS5592687A (en) | 1980-07-14 |
| JPS6215196B2 JPS6215196B2 (en:Method) | 1987-04-06 |
Family
ID=15819185
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP16579878A Granted JPS5592687A (en) | 1978-12-28 | 1978-12-28 | Purification of urokinase |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5592687A (en:Method) |
-
1978
- 1978-12-28 JP JP16579878A patent/JPS5592687A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6215196B2 (en:Method) | 1987-04-06 |
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